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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 17
  • Number 1
  • February 2005

Windows to the Brain

Special Article

Publication date: 01 February 2005

Pages7–19

This review presents data showing that apathy is common across a number of disorders. Apathy is not only common, but is also associated with significant problems: reduced functional level, decreased response to treatment, poor illness outcome, caregiver ...

https://doi.org/10.1176/jnp.17.1.7

Publication date: 01 February 2005

Pages20–28

Mood disorders in patients with epilepsy are not frequently diagnosed and not treated. Because of the high prevalence of depression and the resulting high suicide rate, precise diagnosis and effective therapy are very important. Frequently, the clinical ...

https://doi.org/10.1176/jnp.17.1.20

Regular Article

Publication date: 01 February 2005

Pages29–35

Aggression is a common and costly problem in youth with developmental disabilities. Rating scales that accurately capture and measure subtypes of aggression phenomenology, frequency and severity are urgently needed, in both clinical practice and research. ...

https://doi.org/10.1176/jnp.17.1.29

Publication date: 01 February 2005

Pages36–44

Violent behavior is a significant problem in the psychiatric hospital setting. Persistently violent patients often require seclusion and/or restraints and typically receive high doses of medication and polypharmacy. Clozapine has been found to be ...

https://doi.org/10.1176/jnp.17.1.36

Publication date: 01 February 2005

Pages45–50

Cataplexy is an intriguing example of how emotions can trigger muscle weakness by activating neural pathways. When associated with excessive daytime sleepiness, cataplexy is considered pathognomonic of narcolepsy. A questionnaire was administered to 55 ...

https://doi.org/10.1176/jnp.17.1.45

Publication date: 01 February 2005

Pages51–60

The authors’ main objective was to investigate the relationship between changes in psychopathological, cognitive and activity of daily living (ADL) instrument scores over 12 months in community-dwelling persons with Alzheimer’s disease (AD). A secondary ...

https://doi.org/10.1176/jnp.17.1.51

Publication date: 01 February 2005

Pages61–65

Traumatic brain injury (TBI) and major depression are neuropsychiatric conditions that have been associated with cognitive dysfunction. The aim of this study was to explore the relationship between major depression and cognitive impairment following mild ...

https://doi.org/10.1176/jnp.17.1.61

Publication date: 01 February 2005

Pages66–74

Patients with damage to the frontal lobes frequently exhibit impaired social behavior, but it is not clear which specific processes are disrupted. The authors investigated the ability to interpret nonverbal emotional expression in patients with lesions ...

https://doi.org/10.1176/jnp.17.1.66

Publication date: 01 February 2005

Pages75–83

Several recent studies using functional magnetic resonance imaging (fMRI) during recognition memory tests have suggested that the ability to neuromodulate as a function of cognitive demand may be impaired in older adults due to age-related cell loss and ...

https://doi.org/10.1176/jnp.17.1.75

Publication date: 01 February 2005

Pages84–90

Visual inspection of the unquantified electroencephalogram (EEG) remains the sole technique to confidently detect epileptiform discharges. Usefulness of this procedure in psychiatric research is hampered by reported prevalence of abnormalities in normal ...

https://doi.org/10.1176/jnp.17.1.84

Publication date: 01 February 2005

Pages91–97

Smith-Magenis Syndrome (SMS) is a complex, pediatric, neurobehavioral, contiguous gene syndrome ascribed to interstitial microdeletion of chromosome 17, band 11.2. The syndrome is characterized by distinctive behavioral, neurocognitive, and ...

https://doi.org/10.1176/jnp.17.1.91

Publication date: 01 February 2005

Pages98–105

The Computer-Administered Neuropsychological Screen for Mild Cognitive Impairment (CANS-MCI), a computer administered, scored, and interpreted touch screen battery was evaluated for its ability to detect mild cognitive impairment. Subjects were three ...

https://doi.org/10.1176/jnp.17.1.98

Publication date: 01 February 2005

Pages106–113

Substantial research has demonstrated that adults with schizophrenia display intellectual decline compared to their premorbid levels of functioning. Research of this type, however, is not as common in adolescents with psychotic disorders. Since many first-...

https://doi.org/10.1176/jnp.17.1.106

Clinical and Research Reports

Publication date: 01 February 2005

Pages114–118

Apathy is a prominent neuropsychiatric symptom associated with human immunodeficiency virus (HIV). The increased frequency of apathy in this population may reflect the direct involvement of the virus on the central nervous system (CNS), but the severity ...

https://doi.org/10.1176/jnp.17.1.114

Publication date: 01 February 2005

Pages119–121

Patients with Huntington’s disease show deficits in recognizing disgust in the facial expressions and vocal intonations of others. In this study, the authors demonstrate that these disgust-related deficits extend to foul-smelling olfactory stimuli and ...

https://doi.org/10.1176/jnp.17.1.119

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