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American Journal of Psychiatry

  • Volume 161
  • Number 12
  • December 2004

In This Issue

Editorial

Reviews and Overviews

Publication date: 01 December 2004

Pages2155–2162

OBJECTIVE: Depression is common, costly, treatable, and a major influence on quality of life. Cost-utility analysis combines costs with quantity and quality of life into a metric that is meaningful for studies of interventions or care strategies and is ...

https://doi.org/10.1176/appi.ajp.161.12.2155

Publication date: 01 December 2004

Pages2163–2177

OBJECTIVE: The Hamilton Depression Rating Scale has been the gold standard for the assessment of depression for more than 40 years. Criticism of the instrument has been increasing. The authors review studies published since the last major review of this ...

https://doi.org/10.1176/appi.ajp.161.12.2163

Images in Neuroscience

Introspections

Clinical Case Conference

Images in Psychiatry

Article

Publication date: 01 December 2004

Pages2186–2193

OBJECTIVE: Disturbances in the metabolism of the brain amino acid transmitter γ-aminobutyric acid (GABA) may contribute to the pathophysiology of human anxiety disorders. Animal studies indicate that deletions or reductions in the expression of the gene ...

https://doi.org/10.1176/appi.ajp.161.12.2186

Publication date: 01 December 2004

Pages2194–2200

OBJECTIVE: Increasing evidence suggests that posttraumatic stress disorder (PTSD) is associated with small hippocampal size. The authors compared trauma-exposed subjects with PTSD and trauma-exposed subjects without PTSD to clarify whether small ...

https://doi.org/10.1176/appi.ajp.161.12.2194

Publication date: 01 December 2004

Pages2201–2206

OBJECTIVE: The authors examine the functional anatomy of serotonergic and dopaminergic systems in obsessive-compulsive disorder in psychotropic-naive patients without comorbidity. METHOD: [123I]β-CIT binding patterns for dopamine and serotonin ...

https://doi.org/10.1176/appi.ajp.161.12.2201

Publication date: 01 December 2004

Pages2207–2214

OBJECTIVE: The purpose of the study was to examine the relationship between panic attack and the onset of specific mental disorders and severe psychopathology across the diagnostic spectrum among adolescents and young adults. METHOD: Data were drawn from ...

https://doi.org/10.1176/appi.ajp.161.12.2207

Publication date: 01 December 2004

Pages2215–2221

OBJECTIVE: A large and well-characterized sample of individuals with anorexia nervosa and bulimia nervosa from the Price Foundation collaborative genetics study was used to determine the frequency of anxiety disorders and to understand how anxiety ...

https://doi.org/10.1176/appi.ajp.161.12.2215

Publication date: 01 December 2004

Pages2230–2237

OBJECTIVE: This study evaluated quality of care for primary care patients with anxiety disorders in university-affiliated outpatient clinics in Los Angeles, San Diego, and Seattle. METHOD: Three hundred sixty-six primary care outpatients who were ...

https://doi.org/10.1176/appi.ajp.161.12.2230

Publication date: 01 December 2004

Pages2238–2244

OBJECTIVE: Mood and reproductive function were prospectively evaluated in asymptomatic premenopausal women to determine whether the onset of depression was temporally linked to the perimenopause. METHOD: Twenty-nine asymptomatic, regularly cycling women ...

https://doi.org/10.1176/appi.ajp.161.12.2238

Publication date: 01 December 2004

Pages2245–2256

OBJECTIVE: Separation from loved ones commonly leads to grief reactions. In some individuals, grief can evolve into a major depressive episode. The brain regions involved in grief have not been specifically studied. The authors studied brain activity in ...

https://doi.org/10.1176/appi.ajp.161.12.2245

Publication date: 01 December 2004

Pages2257–2262

OBJECTIVE: Many terminally ill patients enroll in a hospice late in their illness, and recent data indicate decreasing lengths of hospice enrollment, yet we know little about the impact of hospice enrollment length on surviving caregivers. This is the ...

https://doi.org/10.1176/appi.ajp.161.12.2257

Publication date: 01 December 2004

Pages2263–2270

OBJECTIVE: Patients experiencing their first major depressive episode after receiving a diagnosis of cancer are frequently seen in clinical oncology settings; however, little is known about the neurobiological basis of the first episode. In previous ...

https://doi.org/10.1176/appi.ajp.161.12.2263

Publication date: 01 December 2004

Pages2271–2276

OBJECTIVE: The aim of this study was to evaluate dissociative disorder and overall psychiatric comorbidity in patients with conversion disorder. METHOD: Thirty-eight consecutive patients previously diagnosed with conversion disorder were evaluated in two ...

https://doi.org/10.1176/ajp.161.12.2271

Publication date: 01 December 2004

Pages2277–2281

OBJECTIVE: The authors examined predictors of premature dropout from a voluntary specialized inpatient treatment program for anorexia nervosa. METHOD: One hundred sixty-six consecutive patients with anorexia nervosa received an admission assessment that ...

https://doi.org/10.1176/appi.ajp.161.12.2277

Publication date: 01 December 2004

Pages2282–2286

OBJECTIVE: An extensive literature has demonstrated a relationship between hospital volume and outcomes for surgical care and other medical procedures. The authors examined whether an analogous association exists between the volume of mental health ...

https://doi.org/10.1176/appi.ajp.161.12.2282

Publication date: 01 December 2004

Pages2287–2294

OBJECTIVE: The purpose of this study was to determine the rates and predictors of HIV testing and receipt of results among homeless adults with serious mental illness in the initial 3-month period after contact with a community-based case management ...

https://doi.org/10.1176/appi.ajp.161.12.2287

Publication date: 01 December 2004

Pages2295–2302

OBJECTIVE: Physicians’ suicide rates have repeatedly been reported to be higher than those of the general population or other academics, but uncertainty remains. In this study, physicians’ suicide rate ratios were estimated with a meta-analysis and ...

https://doi.org/10.1176/appi.ajp.161.12.2295

Publication date: 01 December 2004

Pages2303–2308

OBJECTIVE: Few studies have investigated the association between religion and suicide either in terms of Durkheim’s social integration hypothesis or the hypothesis of the regulative benefits of religion. The relationship between religion and suicide ...

https://doi.org/10.1176/appi.ajp.161.12.2303

Brief Report

Publication date: 01 December 2004

Pages2309–2311

OBJECTIVE: Several safeguards have been developed to protect research volunteers, but little is known about how the people involved in this research—the stakeholders—view these efforts to assure participant rights and well-being. The authors’ goal was to ...

https://doi.org/10.1176/ajp.161.12.2309

Publication date: 01 December 2004

Pages2309–2311

OBJECTIVE: Several safeguards have been developed to protect research volunteers, but little is known about how the people involved in this research—the stakeholders—view these efforts to assure participant rights and well-being. The authors’ goal was to ...

https://doi.org/10.1176/appi.ajp.161.12.2309

Publication date: 01 December 2004

Pages2312–2314

OBJECTIVE: This study replicated a previous report that there may be substantial synergism between urbanicity (a proxy environmental risk factor) and familial clustering of psychotic disorder (a proxy genetic risk factor). METHOD: The amount of synergism ...

https://doi.org/10.1176/ajp.161.12.2312

Publication date: 01 December 2004

Pages2312–2314

OBJECTIVE: This study replicated a previous report that there may be substantial synergism between urbanicity (a proxy environmental risk factor) and familial clustering of psychotic disorder (a proxy genetic risk factor). METHOD: The amount of synergism ...

https://doi.org/10.1176/appi.ajp.161.12.2312

Publication date: 01 December 2004

Pages2314–2316

OBJECTIVE: Anatomical and functional deficits of the olfactory neural system have been identified in patients with schizophrenia. Since olfactory structures develop in conjunction with both the palate and ventral forebrain, the authors hypothesized that ...

https://doi.org/10.1176/ajp.161.12.2314

Publication date: 01 December 2004

Pages2314–2316

OBJECTIVE: Anatomical and functional deficits of the olfactory neural system have been identified in patients with schizophrenia. Since olfactory structures develop in conjunction with both the palate and ventral forebrain, the authors hypothesized that ...

https://doi.org/10.1176/appi.ajp.161.12.2314

Publication date: 01 December 2004

Pages2317–2319

OBJECTIVE: Individuals with serious mental illness have elevated smoking rates, and smoking is a significant risk factor for chronic obstructive pulmonary disease (COPD). The goal was to determine the prevalence of COPD among those with serious mental ...

https://doi.org/10.1176/ajp.161.12.2317

Publication date: 01 December 2004

Pages2317–2319

OBJECTIVE: Individuals with serious mental illness have elevated smoking rates, and smoking is a significant risk factor for chronic obstructive pulmonary disease (COPD). The goal was to determine the prevalence of COPD among those with serious mental ...

https://doi.org/10.1176/appi.ajp.161.12.2317

Publication date: 01 December 2004

Pages2320–2322

OBJECTIVE: This study examined associations between functional polymorphism (Val108/158 Met) in the catechol O-methyltransferase (COMT) gene and eye tracking measures in schizophrenia. METHOD: Predictive pursuit and closed-loop gains of 62 patients with ...

https://doi.org/10.1176/ajp.161.12.2320

Publication date: 01 December 2004

Pages2320–2322

OBJECTIVE: This study examined associations between functional polymorphism (Val108/158 Met) in the catechol O-methyltransferase (COMT) gene and eye tracking measures in schizophrenia. METHOD: Predictive pursuit and closed-loop gains of 62 patients with ...

https://doi.org/10.1176/appi.ajp.161.12.2320

Publication date: 01 December 2004

Pages2322–2324

OBJECTIVE: The authors’ goal was to identify predictors of treatment response in bulimia nervosa and, in particular, to attempt to replicate and extend the observation that early change predicts outcome. METHOD: Predictors of response at the end of ...

https://doi.org/10.1176/ajp.161.12.2322

Publication date: 01 December 2004

Pages2322–2324

OBJECTIVE: The authors’ goal was to identify predictors of treatment response in bulimia nervosa and, in particular, to attempt to replicate and extend the observation that early change predicts outcome. METHOD: Predictors of response at the end of ...

https://doi.org/10.1176/appi.ajp.161.12.2322

Letter to the Editor

Book Forum: Literature

Book Forum: Love

Book Forum: History

Book Forum: Biographies

Correction

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