American Journal of Psychiatry
- Volume 161
- Number 12
- December 2004
In This Issue
Editorial
Reviews and Overviews
Publication date: 01 December 2004
Pages2155–2162OBJECTIVE: Depression is common, costly, treatable, and a major influence on quality of life. Cost-utility analysis combines costs with quantity and quality of life into a metric that is meaningful for studies of interventions or care strategies and is ...
https://doi.org/10.1176/appi.ajp.161.12.2155Publication date: 01 December 2004
Pages2163–2177OBJECTIVE: The Hamilton Depression Rating Scale has been the gold standard for the assessment of depression for more than 40 years. Criticism of the instrument has been increasing. The authors review studies published since the last major review of this ...
https://doi.org/10.1176/appi.ajp.161.12.2163Images in Neuroscience
Introspections
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 December 2004
Pages2186–2193OBJECTIVE: Disturbances in the metabolism of the brain amino acid transmitter γ-aminobutyric acid (GABA) may contribute to the pathophysiology of human anxiety disorders. Animal studies indicate that deletions or reductions in the expression of the gene ...
https://doi.org/10.1176/appi.ajp.161.12.2186Publication date: 01 December 2004
Pages2194–2200OBJECTIVE: Increasing evidence suggests that posttraumatic stress disorder (PTSD) is associated with small hippocampal size. The authors compared trauma-exposed subjects with PTSD and trauma-exposed subjects without PTSD to clarify whether small ...
https://doi.org/10.1176/appi.ajp.161.12.2194Publication date: 01 December 2004
Pages2201–2206OBJECTIVE: The authors examine the functional anatomy of serotonergic and dopaminergic systems in obsessive-compulsive disorder in psychotropic-naive patients without comorbidity. METHOD: [123I]β-CIT binding patterns for dopamine and serotonin ...
https://doi.org/10.1176/appi.ajp.161.12.2201Publication date: 01 December 2004
Pages2207–2214OBJECTIVE: The purpose of the study was to examine the relationship between panic attack and the onset of specific mental disorders and severe psychopathology across the diagnostic spectrum among adolescents and young adults. METHOD: Data were drawn from ...
https://doi.org/10.1176/appi.ajp.161.12.2207Publication date: 01 December 2004
Pages2215–2221OBJECTIVE: A large and well-characterized sample of individuals with anorexia nervosa and bulimia nervosa from the Price Foundation collaborative genetics study was used to determine the frequency of anxiety disorders and to understand how anxiety ...
https://doi.org/10.1176/appi.ajp.161.12.2215Publication date: 01 December 2004
Pages2222–2229OBJECTIVE: The authors provide a detailed perspective on the correlates of comorbid anxiety in a large, well-characterized sample of bipolar disorder patients. METHOD: Anxiety and its correlates were examined in a cross-sectional sample from the first 500 ...
https://doi.org/10.1176/appi.ajp.161.12.2222Publication date: 01 December 2004
Pages2230–2237OBJECTIVE: This study evaluated quality of care for primary care patients with anxiety disorders in university-affiliated outpatient clinics in Los Angeles, San Diego, and Seattle. METHOD: Three hundred sixty-six primary care outpatients who were ...
https://doi.org/10.1176/appi.ajp.161.12.2230Publication date: 01 December 2004
Pages2238–2244OBJECTIVE: Mood and reproductive function were prospectively evaluated in asymptomatic premenopausal women to determine whether the onset of depression was temporally linked to the perimenopause. METHOD: Twenty-nine asymptomatic, regularly cycling women ...
https://doi.org/10.1176/appi.ajp.161.12.2238Publication date: 01 December 2004
Pages2245–2256OBJECTIVE: Separation from loved ones commonly leads to grief reactions. In some individuals, grief can evolve into a major depressive episode. The brain regions involved in grief have not been specifically studied. The authors studied brain activity in ...
https://doi.org/10.1176/appi.ajp.161.12.2245Publication date: 01 December 2004
Pages2257–2262OBJECTIVE: Many terminally ill patients enroll in a hospice late in their illness, and recent data indicate decreasing lengths of hospice enrollment, yet we know little about the impact of hospice enrollment length on surviving caregivers. This is the ...
https://doi.org/10.1176/appi.ajp.161.12.2257Publication date: 01 December 2004
Pages2263–2270OBJECTIVE: Patients experiencing their first major depressive episode after receiving a diagnosis of cancer are frequently seen in clinical oncology settings; however, little is known about the neurobiological basis of the first episode. In previous ...
https://doi.org/10.1176/appi.ajp.161.12.2263Publication date: 01 December 2004
Pages2271–2276OBJECTIVE: The aim of this study was to evaluate dissociative disorder and overall psychiatric comorbidity in patients with conversion disorder. METHOD: Thirty-eight consecutive patients previously diagnosed with conversion disorder were evaluated in two ...
https://doi.org/10.1176/ajp.161.12.2271Publication date: 01 December 2004
Pages2277–2281OBJECTIVE: The authors examined predictors of premature dropout from a voluntary specialized inpatient treatment program for anorexia nervosa. METHOD: One hundred sixty-six consecutive patients with anorexia nervosa received an admission assessment that ...
https://doi.org/10.1176/appi.ajp.161.12.2277Publication date: 01 December 2004
Pages2282–2286OBJECTIVE: An extensive literature has demonstrated a relationship between hospital volume and outcomes for surgical care and other medical procedures. The authors examined whether an analogous association exists between the volume of mental health ...
https://doi.org/10.1176/appi.ajp.161.12.2282Publication date: 01 December 2004
Pages2287–2294OBJECTIVE: The purpose of this study was to determine the rates and predictors of HIV testing and receipt of results among homeless adults with serious mental illness in the initial 3-month period after contact with a community-based case management ...
https://doi.org/10.1176/appi.ajp.161.12.2287Publication date: 01 December 2004
Pages2295–2302OBJECTIVE: Physicians’ suicide rates have repeatedly been reported to be higher than those of the general population or other academics, but uncertainty remains. In this study, physicians’ suicide rate ratios were estimated with a meta-analysis and ...
https://doi.org/10.1176/appi.ajp.161.12.2295Publication date: 01 December 2004
Pages2303–2308OBJECTIVE: Few studies have investigated the association between religion and suicide either in terms of Durkheim’s social integration hypothesis or the hypothesis of the regulative benefits of religion. The relationship between religion and suicide ...
https://doi.org/10.1176/appi.ajp.161.12.2303Brief Report
Publication date: 01 December 2004
Pages2309–2311OBJECTIVE: Several safeguards have been developed to protect research volunteers, but little is known about how the people involved in this research—the stakeholders—view these efforts to assure participant rights and well-being. The authors’ goal was to ...
https://doi.org/10.1176/ajp.161.12.2309Publication date: 01 December 2004
Pages2309–2311OBJECTIVE: Several safeguards have been developed to protect research volunteers, but little is known about how the people involved in this research—the stakeholders—view these efforts to assure participant rights and well-being. The authors’ goal was to ...
https://doi.org/10.1176/appi.ajp.161.12.2309Publication date: 01 December 2004
Pages2312–2314OBJECTIVE: This study replicated a previous report that there may be substantial synergism between urbanicity (a proxy environmental risk factor) and familial clustering of psychotic disorder (a proxy genetic risk factor). METHOD: The amount of synergism ...
https://doi.org/10.1176/ajp.161.12.2312Publication date: 01 December 2004
Pages2312–2314OBJECTIVE: This study replicated a previous report that there may be substantial synergism between urbanicity (a proxy environmental risk factor) and familial clustering of psychotic disorder (a proxy genetic risk factor). METHOD: The amount of synergism ...
https://doi.org/10.1176/appi.ajp.161.12.2312Publication date: 01 December 2004
Pages2314–2316OBJECTIVE: Anatomical and functional deficits of the olfactory neural system have been identified in patients with schizophrenia. Since olfactory structures develop in conjunction with both the palate and ventral forebrain, the authors hypothesized that ...
https://doi.org/10.1176/ajp.161.12.2314Publication date: 01 December 2004
Pages2314–2316OBJECTIVE: Anatomical and functional deficits of the olfactory neural system have been identified in patients with schizophrenia. Since olfactory structures develop in conjunction with both the palate and ventral forebrain, the authors hypothesized that ...
https://doi.org/10.1176/appi.ajp.161.12.2314Publication date: 01 December 2004
Pages2317–2319OBJECTIVE: Individuals with serious mental illness have elevated smoking rates, and smoking is a significant risk factor for chronic obstructive pulmonary disease (COPD). The goal was to determine the prevalence of COPD among those with serious mental ...
https://doi.org/10.1176/ajp.161.12.2317Publication date: 01 December 2004
Pages2317–2319OBJECTIVE: Individuals with serious mental illness have elevated smoking rates, and smoking is a significant risk factor for chronic obstructive pulmonary disease (COPD). The goal was to determine the prevalence of COPD among those with serious mental ...
https://doi.org/10.1176/appi.ajp.161.12.2317Publication date: 01 December 2004
Pages2320–2322OBJECTIVE: This study examined associations between functional polymorphism (Val108/158 Met) in the catechol O-methyltransferase (COMT) gene and eye tracking measures in schizophrenia. METHOD: Predictive pursuit and closed-loop gains of 62 patients with ...
https://doi.org/10.1176/ajp.161.12.2320Publication date: 01 December 2004
Pages2320–2322OBJECTIVE: This study examined associations between functional polymorphism (Val108/158 Met) in the catechol O-methyltransferase (COMT) gene and eye tracking measures in schizophrenia. METHOD: Predictive pursuit and closed-loop gains of 62 patients with ...
https://doi.org/10.1176/appi.ajp.161.12.2320Publication date: 01 December 2004
Pages2322–2324OBJECTIVE: The authors’ goal was to identify predictors of treatment response in bulimia nervosa and, in particular, to attempt to replicate and extend the observation that early change predicts outcome. METHOD: Predictors of response at the end of ...
https://doi.org/10.1176/ajp.161.12.2322Publication date: 01 December 2004
Pages2322–2324OBJECTIVE: The authors’ goal was to identify predictors of treatment response in bulimia nervosa and, in particular, to attempt to replicate and extend the observation that early change predicts outcome. METHOD: Predictors of response at the end of ...
https://doi.org/10.1176/appi.ajp.161.12.2322