American Journal of Psychiatry
- Volume 161
- Number 11
- November 2004
In This Issue
Editorial
Reviews and Overviews
Publication date: 01 November 2004
Pages1948–1956OBJECTIVE: While it is increasingly recognized that attention deficit hyperactivity disorder (ADHD) persists into adulthood, there is no consensus on diagnostic criteria for adult ADHD. In this article the authors describe and contrast competing ...
https://doi.org/10.1176/appi.ajp.161.11.1948Publication date: 01 November 2004
Pages1957–1966OBJECTIVE: Several studies have found reduced hippocampal volume in patients with unipolar depression, but discrepancies exist. The authors performed a systematic review and meta-analysis of volumetric studies of the hippocampus in patients with mood ...
https://doi.org/10.1176/appi.ajp.161.11.1957Publication date: 01 November 2004
Pages1967–1977The authors review the literature examining the validity and significance of cannabis withdrawal syndrome. Findings from animal laboratory research are briefly reviewed, and human laboratory and clinical studies are surveyed in more detail. Converging ...
https://doi.org/10.1176/appi.ajp.161.11.1967Images in Neuroscience
Introspections
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 November 2004
Pages1990–1997OBJECTIVE: Recent studies have suggested that attention deficit hyperactivity disorder (ADHD) is associated with abnormalities in basal ganglia and prefrontal cortical functioning. However, these studies have primarily relied upon cognitive tasks that ...
https://doi.org/10.1176/appi.ajp.161.11.1990Publication date: 01 November 2004
Pages1998–2004OBJECTIVE: This study investigated whether a melancholic subtype similar to that established in depressed adults can be identified in depressed preschool children. METHOD: A final group total of 156 preschool children between the ages of 3.0 and 5.6 years ...
https://doi.org/10.1176/appi.ajp.161.11.1998Publication date: 01 November 2004
Pages2005–2013OBJECTIVE: Poor nutrition is thought to predispose to externalizing behavior problems, but to date there appear to have been no prospective longitudinal studies testing this hypothesis. This study assessed whether 1) poor nutrition at age 3 years ...
https://doi.org/10.1176/appi.ajp.161.11.2005Publication date: 01 November 2004
Pages2014–2020OBJECTIVE: Predictive validity is a fundamental consideration in evaluating the DSM-IV diagnostic criteria for attention deficit hyperactivity disorder (ADHD), particularly for younger children. METHOD: The authors conducted four annual assessments of ...
https://doi.org/10.1176/appi.ajp.161.11.2014Publication date: 01 November 2004
Pages2021–2027OBJECTIVE: The authors examined videotaped behaviors of children who developed schizophrenia as adults and of comparison subjects to disclose possible social and neuromotor deficits foreshadowing later development of schizophrenia. METHOD: In 1972, a ...
https://doi.org/10.1176/appi.ajp.161.11.2021Publication date: 01 November 2004
Pages2028–2037OBJECTIVE: The corpus callosum is the major commissure connecting the cerebral hemispheres. Prior evidence suggests involvement of the corpus callosum in the pathophysiology of Tourette’s disorder. The authors assessed corpus callosum size and anatomical ...
https://doi.org/10.1176/appi.ajp.161.11.2028Publication date: 01 November 2004
Pages2038–2044OBJECTIVE: Structural and functional abnormalities in the medial temporal lobe, particularly the hippocampus and amygdala, have been described in people with autism. The authors hypothesized that parents of children with a diagnosis of autistic disorder ...
https://doi.org/10.1176/appi.ajp.161.11.2038Publication date: 01 November 2004
Pages2045–2049OBJECTIVE: The authors examined which, if any, research design features and patient characteristics would significantly differ between successful and unsuccessful antidepressant trials. METHOD: Clinical trial data were reviewed for nine antidepressants ...
https://doi.org/10.1176/appi.ajp.161.11.2045Publication date: 01 November 2004
Pages2050–2059OBJECTIVE: This study determined the efficacy of antidepressant medication for the treatment of depression in the “old-old.” METHOD: This randomized 8-week medication trial compared citalopram, 10–40 mg/day, to placebo in the treatment of patients 75 and ...
https://doi.org/10.1176/appi.ajp.161.11.2050Publication date: 01 November 2004
Pages2060–2065OBJECTIVE: This study was designed to compare the efficacy of two two-phase pharmacological treatment strategies for inpatients with DSM-IV major depressive disorder. METHOD: During phase I, patients participated in a double-blind study of the effects of ...
https://doi.org/10.1176/appi.ajp.161.11.2060Publication date: 01 November 2004
Pages2066–2072OBJECTIVE: β-Arrestins play a pivotal role in G protein-coupled receptor desensitization. β-Arrestins interfere in G protein receptor interaction, thus leading to desensitization of G protein-mediated receptor signaling. G protein receptor signaling and ...
https://doi.org/10.1176/appi.ajp.161.11.2066Publication date: 01 November 2004
Pages2073–2080OBJECTIVE: Previous research suggests that the comorbidity of major depression with a personality disorder, especially borderline personality disorder, is associated with a poorer response to ECT. The authors compared the acute outcome of ECT in depressed ...
https://doi.org/10.1176/appi.ajp.161.11.2073Publication date: 01 November 2004
Pages2081–2090OBJECTIVE: This study determined whether cognitive impairments and structural brain changes in older depressed subjects, especially in the hippocampus, are related to hypercortisolemia. METHOD: Sixty-one depressed subjects over age 60 who met DSM-IV ...
https://doi.org/10.1176/appi.ajp.161.11.2081Publication date: 01 November 2004
Pages2091–2099OBJECTIVE: The authors used magnetic resonance imaging and an image analysis technique known as cortical pattern matching to map cortical gray matter deficits in elderly depressed patients with an illness onset after age 60 (late-onset depression). METHOD:...
https://doi.org/10.1176/appi.ajp.161.11.2091Publication date: 01 November 2004
Pages2100–2107OBJECTIVE: Accepted treatments for cigarette smoking rarely achieve abstinence rates of >35% at 1 year. Low rates may reflect failure to provide extended and multifocal treatment for this complex and chronic addiction. Using a chronic disease model of ...
https://doi.org/10.1176/appi.ajp.161.11.2100Publication date: 01 November 2004
Pages2108–2114OBJECTIVE: The purpose of this study was to assess the prevalence of axis I disorders among patients with borderline personality disorder over 6 years of prospective follow-up. METHOD: A semistructured interview of demonstrated reliability was used to ...
https://doi.org/10.1176/appi.ajp.161.11.2108Brief Report
Publication date: 01 November 2004
Pages2115–2117OBJECTIVE: The authors assessed the effects of d-cycloserine on the core symptom of social impairment in subjects with autism. METHOD: Following a 2-week, single-blind placebo lead-in phase, drug-free subjects with autistic disorder were administered ...
https://doi.org/10.1176/appi.ajp.161.11.2115Publication date: 01 November 2004
Pages2117–2120OBJECTIVE: The authors have previously described less activation of left speech-related temporal areas in adults with autism when listening to speech-like sounds than in normal adults. Here, they investigated whether this abnormal cortical processing was ...
https://doi.org/10.1176/appi.ajp.161.11.2117Publication date: 01 November 2004
Pages2121–2123OBJECTIVE: There may be an association between a low serum cholesterol level and dissociative disorders. METHOD: The subjects of the study were 16 patients with dissociative disorder and 16 normal comparison subjects (two men and 14 women in each group). ...
https://doi.org/10.1176/appi.ajp.161.11.2121Publication date: 01 November 2004
Pages2123–2126OBJECTIVE: The authors examined the relationship between cholesterol metabolism and suicidality in carriers of Smith-Lemli-Opitz syndrome and their families. This population has a partial deficiency in 7-dehydrocholesterol reductase (DHCR7), the enzyme ...
https://doi.org/10.1176/appi.ajp.161.11.2123Publication date: 01 November 2004
Pages2126–2128OBJECTIVE: The authors investigated the neurobiological basis of poor sleep and daytime fatigue in insomnia. METHOD: [18F]Fluorodeoxyglucose positron emission tomography was used to assess regional cerebral glucose metabolism of seven patients with ...
https://doi.org/10.1176/appi.ajp.161.11.2126Publication date: 01 November 2004
Pages2129–2131OBJECTIVE: The authors examined psychiatric diagnoses of all individuals convicted of homicide and attempted homicide in Sweden from 1988 to 2001 (N=2,005). METHOD: High-quality national crime and hospital registers were linked to investigate standardized ...
https://doi.org/10.1176/appi.ajp.161.11.2129