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American Journal of Psychiatry

  • Volume 161
  • Number 11
  • November 2004

In This Issue

Editorial

Reviews and Overviews

Publication date: 01 November 2004

Pages1948–1956

OBJECTIVE: While it is increasingly recognized that attention deficit hyperactivity disorder (ADHD) persists into adulthood, there is no consensus on diagnostic criteria for adult ADHD. In this article the authors describe and contrast competing ...

https://doi.org/10.1176/appi.ajp.161.11.1948

Publication date: 01 November 2004

Pages1957–1966

OBJECTIVE: Several studies have found reduced hippocampal volume in patients with unipolar depression, but discrepancies exist. The authors performed a systematic review and meta-analysis of volumetric studies of the hippocampus in patients with mood ...

https://doi.org/10.1176/appi.ajp.161.11.1957

Publication date: 01 November 2004

Pages1967–1977

The authors review the literature examining the validity and significance of cannabis withdrawal syndrome. Findings from animal laboratory research are briefly reviewed, and human laboratory and clinical studies are surveyed in more detail. Converging ...

https://doi.org/10.1176/appi.ajp.161.11.1967

Images in Neuroscience

Introspections

Clinical Case Conference

Images in Psychiatry

Article

Publication date: 01 November 2004

Pages1990–1997

OBJECTIVE: Recent studies have suggested that attention deficit hyperactivity disorder (ADHD) is associated with abnormalities in basal ganglia and prefrontal cortical functioning. However, these studies have primarily relied upon cognitive tasks that ...

https://doi.org/10.1176/appi.ajp.161.11.1990

Publication date: 01 November 2004

Pages1998–2004

OBJECTIVE: This study investigated whether a melancholic subtype similar to that established in depressed adults can be identified in depressed preschool children. METHOD: A final group total of 156 preschool children between the ages of 3.0 and 5.6 years ...

https://doi.org/10.1176/appi.ajp.161.11.1998

Publication date: 01 November 2004

Pages2005–2013

OBJECTIVE: Poor nutrition is thought to predispose to externalizing behavior problems, but to date there appear to have been no prospective longitudinal studies testing this hypothesis. This study assessed whether 1) poor nutrition at age 3 years ...

https://doi.org/10.1176/appi.ajp.161.11.2005

Publication date: 01 November 2004

Pages2014–2020

OBJECTIVE: Predictive validity is a fundamental consideration in evaluating the DSM-IV diagnostic criteria for attention deficit hyperactivity disorder (ADHD), particularly for younger children. METHOD: The authors conducted four annual assessments of ...

https://doi.org/10.1176/appi.ajp.161.11.2014

Publication date: 01 November 2004

Pages2021–2027

OBJECTIVE: The authors examined videotaped behaviors of children who developed schizophrenia as adults and of comparison subjects to disclose possible social and neuromotor deficits foreshadowing later development of schizophrenia. METHOD: In 1972, a ...

https://doi.org/10.1176/appi.ajp.161.11.2021

Publication date: 01 November 2004

Pages2028–2037

OBJECTIVE: The corpus callosum is the major commissure connecting the cerebral hemispheres. Prior evidence suggests involvement of the corpus callosum in the pathophysiology of Tourette’s disorder. The authors assessed corpus callosum size and anatomical ...

https://doi.org/10.1176/appi.ajp.161.11.2028

Publication date: 01 November 2004

Pages2038–2044

OBJECTIVE: Structural and functional abnormalities in the medial temporal lobe, particularly the hippocampus and amygdala, have been described in people with autism. The authors hypothesized that parents of children with a diagnosis of autistic disorder ...

https://doi.org/10.1176/appi.ajp.161.11.2038

Publication date: 01 November 2004

Pages2045–2049

OBJECTIVE: The authors examined which, if any, research design features and patient characteristics would significantly differ between successful and unsuccessful antidepressant trials. METHOD: Clinical trial data were reviewed for nine antidepressants ...

https://doi.org/10.1176/appi.ajp.161.11.2045

Publication date: 01 November 2004

Pages2050–2059

OBJECTIVE: This study determined the efficacy of antidepressant medication for the treatment of depression in the “old-old.” METHOD: This randomized 8-week medication trial compared citalopram, 10–40 mg/day, to placebo in the treatment of patients 75 and ...

https://doi.org/10.1176/appi.ajp.161.11.2050

Publication date: 01 November 2004

Pages2060–2065

OBJECTIVE: This study was designed to compare the efficacy of two two-phase pharmacological treatment strategies for inpatients with DSM-IV major depressive disorder. METHOD: During phase I, patients participated in a double-blind study of the effects of ...

https://doi.org/10.1176/appi.ajp.161.11.2060

Publication date: 01 November 2004

Pages2066–2072

OBJECTIVE: β-Arrestins play a pivotal role in G protein-coupled receptor desensitization. β-Arrestins interfere in G protein receptor interaction, thus leading to desensitization of G protein-mediated receptor signaling. G protein receptor signaling and ...

https://doi.org/10.1176/appi.ajp.161.11.2066

Publication date: 01 November 2004

Pages2073–2080

OBJECTIVE: Previous research suggests that the comorbidity of major depression with a personality disorder, especially borderline personality disorder, is associated with a poorer response to ECT. The authors compared the acute outcome of ECT in depressed ...

https://doi.org/10.1176/appi.ajp.161.11.2073

Publication date: 01 November 2004

Pages2081–2090

OBJECTIVE: This study determined whether cognitive impairments and structural brain changes in older depressed subjects, especially in the hippocampus, are related to hypercortisolemia. METHOD: Sixty-one depressed subjects over age 60 who met DSM-IV ...

https://doi.org/10.1176/appi.ajp.161.11.2081

Publication date: 01 November 2004

Pages2091–2099

OBJECTIVE: The authors used magnetic resonance imaging and an image analysis technique known as cortical pattern matching to map cortical gray matter deficits in elderly depressed patients with an illness onset after age 60 (late-onset depression). METHOD:...

https://doi.org/10.1176/appi.ajp.161.11.2091

Publication date: 01 November 2004

Pages2100–2107

OBJECTIVE: Accepted treatments for cigarette smoking rarely achieve abstinence rates of >35% at 1 year. Low rates may reflect failure to provide extended and multifocal treatment for this complex and chronic addiction. Using a chronic disease model of ...

https://doi.org/10.1176/appi.ajp.161.11.2100

Publication date: 01 November 2004

Pages2108–2114

OBJECTIVE: The purpose of this study was to assess the prevalence of axis I disorders among patients with borderline personality disorder over 6 years of prospective follow-up. METHOD: A semistructured interview of demonstrated reliability was used to ...

https://doi.org/10.1176/appi.ajp.161.11.2108

Brief Report

Publication date: 01 November 2004

Pages2115–2117

OBJECTIVE: The authors assessed the effects of d-cycloserine on the core symptom of social impairment in subjects with autism. METHOD: Following a 2-week, single-blind placebo lead-in phase, drug-free subjects with autistic disorder were administered ...

https://doi.org/10.1176/appi.ajp.161.11.2115

Publication date: 01 November 2004

Pages2121–2123

OBJECTIVE: There may be an association between a low serum cholesterol level and dissociative disorders. METHOD: The subjects of the study were 16 patients with dissociative disorder and 16 normal comparison subjects (two men and 14 women in each group). ...

https://doi.org/10.1176/appi.ajp.161.11.2121

Publication date: 01 November 2004

Pages2123–2126

OBJECTIVE: The authors examined the relationship between cholesterol metabolism and suicidality in carriers of Smith-Lemli-Opitz syndrome and their families. This population has a partial deficiency in 7-dehydrocholesterol reductase (DHCR7), the enzyme ...

https://doi.org/10.1176/appi.ajp.161.11.2123

Publication date: 01 November 2004

Pages2126–2128

OBJECTIVE: The authors investigated the neurobiological basis of poor sleep and daytime fatigue in insomnia. METHOD: [18F]Fluorodeoxyglucose positron emission tomography was used to assess regional cerebral glucose metabolism of seven patients with ...

https://doi.org/10.1176/appi.ajp.161.11.2126

Publication date: 01 November 2004

Pages2129–2131

OBJECTIVE: The authors examined psychiatric diagnoses of all individuals convicted of homicide and attempted homicide in Sweden from 1988 to 2001 (N=2,005). METHOD: High-quality national crime and hospital registers were linked to investigate standardized ...

https://doi.org/10.1176/appi.ajp.161.11.2129

Letter to the Editor

Book Forum: Textbooks

Book Forum: Mood Disorders

Book Forum: Addictive Disorders

Book Forum: Somatic and Cognitive Behavior Treatments

Book Forum: Somatic and Cognitive Behavior Treatments

Correction

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