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American Journal of Psychiatry

  • Volume 161
  • Number 10
  • October 2004

In This Issue

Editorial

Reviews and Overviews

Publication date: 01 October 2004

Pages1743–1754

OBJECTIVE: Researchers have advocated replacing the DSM-IV classification of personality disorders with an alternative diagnostic system based on the five-factor model. This study evaluates the clinical comprehensiveness of the five-factor model and ...

https://doi.org/10.1176/ajp.161.10.1743

Publication date: 01 October 2004

Pages1755–1763

The address of the retiring president of the American Psychiatric Association has been a traditional part of the annual meeting of the association since 1883. The presidential address, which has explicitly been exempted from general discussion or ...

https://doi.org/10.1176/ajp.161.10.1755

Images in Neuroscience

Introspections

Images in Psychiatry

Presidential Paper

Article

Publication date: 01 October 2004

Pages1776–1782

OBJECTIVE: A family history of alcoholism is a risk factor for the development of ethanol dependence. Ethanol is an antagonist of the N-methyl-d-aspartate (NMDA) glutamate receptor, and alterations in NMDA receptor function are thought to be involved in ...

https://doi.org/10.1176/ajp.161.10.1776

Publication date: 01 October 2004

Pages1790–1797

OBJECTIVE: This study examined the extent and characteristics of alcohol dependence and the perceived need for and use of alcohol treatment services among women compared with men in a nonclinical sample of adults 18–64 years of age. METHOD: Data were ...

https://doi.org/10.1176/ajp.161.10.1790

Publication date: 01 October 2004

Pages1806–1813

OBJECTIVE: In a previous study, the authors reported that patients with schizophrenia show subcortical-limbic hypoactivity during sadness. In this study, they capitalized on those findings in order to assess the genetic influence of negative mood ...

https://doi.org/10.1176/ajp.161.10.1806

Publication date: 01 October 2004

Pages1814–1821

OBJECTIVE: The few studies of bipolar I disorder in twins have consistently emphasized the genetic contribution to disease liability. The authors report what appears to be the first twin study of bipolar I disorder involving a population-based twin sample,...

https://doi.org/10.1176/ajp.161.10.1814

Publication date: 01 October 2004

Pages1822–1828

OBJECTIVE: Sensory gating deficits found in schizophrenia can be assessed by using a paired auditory stimulus paradigm to measure auditory evoked response. The ratio of the P50 response amplitude of the second or test stimulus to that of the first or ...

https://doi.org/10.1176/ajp.161.10.1822

Publication date: 01 October 2004

Pages1829–1836

OBJECTIVE: A follow-up study of patients with schizophrenia was conducted to examine change in striatal volumes and extrapyramidal symptoms after a change in medication. METHOD: Thirty-seven patients with schizophrenia and 23 healthy volunteers were ...

https://doi.org/10.1176/ajp.161.10.1829

Publication date: 01 October 2004

Pages1837–1847

OBJECTIVE: Limited randomized, controlled trial data exist on possible differences between atypical antipsychotics in efficacy, overall tolerability, and important indices of health status. The authors compared the efficacy and tolerability of ziprasidone ...

https://doi.org/10.1176/ajp.161.10.1837

Publication date: 01 October 2004

Pages1848–1855

OBJECTIVE: Aberrant synaptic connectivity may underlie the involvement of the hippocampus in schizophrenia. There is reasonable neuropathological evidence for a presynaptic pathology but few studies of the postsynaptic component. This study tested the ...

https://doi.org/10.1176/ajp.161.10.1848

Publication date: 01 October 2004

Pages1856–1863

OBJECTIVE: Sleep disturbances characterize depression and may reflect the abnormal persistence of brain activity from wakefulness into non-REM sleep. The goal of this study was to investigate the functional neuroanatomical correlates of non-REM sleep ...

https://doi.org/10.1176/ajp.161.10.1856

Publication date: 01 October 2004

Pages1864–1871

OBJECTIVE: Minor depressive disorder is both common and associated with significant psychosocial impairment. This study examined antidepressant treatment efficacy in a large group of patients with minor depressive disorder. METHOD: One hundred sixty-two ...

https://doi.org/10.1176/ajp.161.10.1864

Publication date: 01 October 2004

Pages1872–1876

OBJECTIVE: A paucity of studies use nonpharmacological strategies for preventing recurrence in depression. Cognitive behavior treatment of residual symptoms was found to yield a significantly lower relapse rate than clinical management in recurrent ...

https://doi.org/10.1176/ajp.161.10.1872

Publication date: 01 October 2004

Pages1877–1884

OBJECTIVE: To investigate how residual symptoms from an index episode of major depressive disorder may be associated with recurrence, the authors conducted a trial involving four maintenance treatment approaches and examined 1) whether the level and ...

https://doi.org/10.1176/ajp.161.10.1877

Publication date: 01 October 2004

Pages1885–1891

OBJECTIVE: Although major depression is thought to have substantial negative effects on work performance, the possibility of recall bias limits self-report studies of these effects. The authors used the experience sampling method to address this problem ...

https://doi.org/10.1176/ajp.161.10.1885

Publication date: 01 October 2004

Pages1892–1901

OBJECTIVE: The authors’ goal was to assess the adequacy of control, quality of life, and treatment experiences of patients with chronic, recurrent depression being treated by primary care physicians. METHOD: The sample comprised 1,001 patients 18 years ...

https://doi.org/10.1176/ajp.161.10.1892

Brief Report

Publication date: 01 October 2004

Pages1909–1911

OBJECTIVE: This study determined if actors could portray depressed patients to establish the interrater reliability of raters using the Hamilton Depression Rating Scale (HDRS). METHOD: Actors portrayed depressed patients using scripts derived from HDRS ...

https://doi.org/10.1176/ajp.161.10.1909

Publication date: 01 October 2004

Pages1911–1913

OBJECTIVE: Some have suggested that standardized rating scales be used in clinical practice to monitor the course of treatment; however, the time demands of clinical practice make it difficult to use such measures. This study derived a cutoff on a self-...

https://doi.org/10.1176/ajp.161.10.1911

Publication date: 01 October 2004

Pages1913–1916

OBJECTIVE: The authors compared patients who underwent stereotactic subcaudate tractotomy for depression, who were still depressed or recovered from depression, to identify therapeutic mechanisms. METHOD: Ten depressed and eight recovered psychosurgery ...

https://doi.org/10.1176/ajp.161.10.1913

Publication date: 01 October 2004

Pages1916–1918

OBJECTIVE: Bulimia nervosa has been associated with alterations in central serotonergic (5-HT) function. This study investigated iodine-labeled 4-amino-N-[1-[3-(4-fluorophenoxy) propyl]-4-methyl-4-piperidinyl]-5-iodo-2-methoxybenzamide (123I-5-I-R91150) ...

https://doi.org/10.1176/ajp.161.10.1916

Publication date: 01 October 2004

Pages1918–1921

OBJECTIVE: The authors investigated the structural brain correlates of antisaccade performance. METHOD: Magnetic resonance imaging was used to measure the volumes of the prefrontal, premotor, sensorimotor, and occipitoparietal cortices as well as the ...

https://doi.org/10.1176/ajp.161.10.1918

Publication date: 01 October 2004

Pages1922–1924

OBJECTIVE: The authors hypothesized that changes in brain membrane composition resulting from omega-3 fatty acid administration in patients with bipolar disorder would result in greater membrane fluidity, as detected by reductions in T2 values. METHOD: ...

https://doi.org/10.1176/ajp.161.10.1922

Letter to the Editor

Book Forum: Substantial Professional Issues

Book Forum: Nature Versus Nurture

Book Forum: Ethics and Forensics

Book Forum: Mind, Brain, and Imagination

Correction

APA Official Actions

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