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American Journal of Psychiatry

  • Volume 161
  • Number 9
  • September 2004

In This Issue

Editorial

Reviews and Overviews

Publication date: 01 September 2004

Pages1537–1547

OBJECTIVE: This study reviewed the evidence from randomized, controlled trials on the efficacy and safety of antidepressants in the short-term treatment of bipolar depression. METHOD: The authors performed a systematic review and meta-analysis of ...

https://doi.org/10.1176/appi.ajp.161.9.1537

Publication date: 01 September 2004

Pages1548–1557

OBJECTIVE: Although maternal infanticide is a rare event, a high proportion of cases occurs in the context of postpartum mental illness. The author reviews historical, legislative, and contemporary psychiatric perspectives on infanticide and discusses ...

https://doi.org/10.1176/appi.ajp.161.9.1548

Publication date: 01 September 2004

Pages1558–1563

OBJECTIVE: Three domains of ethical conduct outlined in the U.S. Food and Drug Administration’s 1998 Belmont Report on protection of human research subjects—respect for persons, beneficence, and justice—have posed specific dilemmas in the design of ...

https://doi.org/10.1176/appi.ajp.161.9.1558

Images in Neuroscience

Introspections

Clinical Case Conference

Images in Psychiatry

Article

Publication date: 01 September 2004

Pages1581–1587

OBJECTIVE: The authors examined the sources of covariation between generalized anxiety disorder and the personality trait of neuroticism. Because women have higher levels of neuroticism and twice the risk of lifetime generalized anxiety disorder of men, ...

https://doi.org/10.1176/appi.ajp.161.9.1581

Publication date: 01 September 2004

Pages1588–1594

OBJECTIVE: The association between maternal depression and offspring dysfunction is well documented; however, little attention has been paid to psychopathology in the partners of these depressed mothers or to how paternal psychopathology might influence ...

https://doi.org/10.1176/appi.ajp.161.9.1588

Publication date: 01 September 2004

Pages1595–1602

OBJECTIVE: There has been consistent evidence for a lower incidence and milder course of schizophrenia in women, yet there have been very few investigations of sex differences in brain function in this disorder. This study used a new high-temporal-...

https://doi.org/10.1176/appi.ajp.161.9.1595

Publication date: 01 September 2004

Pages1603–1611

OBJECTIVE: The middle temporal gyrus and inferior temporal gyrus subserve language and semantic memory processing, visual perception, and multimodal sensory integration. Functional deficits in these cognitive processes have been well documented in ...

https://doi.org/10.1176/appi.ajp.161.9.1603

Publication date: 01 September 2004

Pages1612–1619

OBJECTIVE: Neuropathological findings regarding the entorhinal cortex in schizophrenia are conflicting. The authors used structural magnetic resonance imaging to examine the entorhinal cortex volumes of healthy subjects and medication-naive patients ...

https://doi.org/10.1176/appi.ajp.161.9.1612

Publication date: 01 September 2004

Pages1620–1625

OBJECTIVE: Clozapine, the prototype of atypical antipsychotics, remains unique in its efficacy in the treatment of refractory schizophrenia. Its affinity for dopamine D4 receptors, serotonin 5-HT2A receptor antagonism, effects on the noradrenergic system, ...

https://doi.org/10.1176/appi.ajp.161.9.1620

Publication date: 01 September 2004

Pages1626–1634

OBJECTIVE: The purpose of the study was to evaluate the prevalence and predictors of depression treatment in a diverse cross-national sample of primary care patients. METHOD: At primary care facilities in six countries (Spain, Israel, Australia, Brazil, ...

https://doi.org/10.1176/appi.ajp.161.9.1626

Publication date: 01 September 2004

Pages1635–1641

OBJECTIVE: Published reports indicate that African Americans are underrepresented among patients treated with ECT. The reason for this disparity in practice has not been determined. This study addressed this question by using existing data on a large ...

https://doi.org/10.1176/appi.ajp.161.9.1635

Publication date: 01 September 2004

Pages1642–1649

OBJECTIVE: Sertraline’s efficacy and tolerability in treating generalized anxiety disorder were evaluated. METHOD: Adult outpatients with DSM-IV generalized anxiety disorder and a total score of 18 or higher on the Hamilton Anxiety Rating Scale were ...

https://doi.org/10.1176/appi.ajp.161.9.1642

Publication date: 01 September 2004

Pages1650–1657

OBJECTIVE: Frontostriatal neural abnormalities have been implicated in the response inhibition impairments that are characteristic of attention deficit hyperactivity disorder (ADHD). However, reports of such abnormalities in adolescents are inconsistent. ...

https://doi.org/10.1176/appi.ajp.161.9.1650

Publication date: 01 September 2004

Pages1658–1664

OBJECTIVE: Training in psychodynamic psychotherapy remains a core requirement of psychiatric residency training programs, yet no standard measures of competency exist to document residents’ knowledge and skills in this area. To address this issue, the ...

https://doi.org/10.1176/appi.ajp.161.9.1658

Publication date: 01 September 2004

Pages1665–1671

OBJECTIVE: This study examined 1) whether patients with chronic and recurrent anxiety and depressive disorders and/or personality disorders demonstrate improvement in their defense styles with long-term dynamic psychotherapy and 2) what the relationship ...

https://doi.org/10.1176/appi.ajp.161.9.1665

Publication date: 01 September 2004

Pages1672–1679

OBJECTIVE: Prior studies have found high rates of alcohol use and abuse/dependence, depression, bankruptcy, and incarceration associated with recreational gambling. Despite growing rates of recreational gambling in older adults, little is known regarding ...

https://doi.org/10.1176/appi.ajp.161.9.1672

Publication date: 01 September 2004

Pages1680–1691

OBJECTIVE: The narrow ICD-10 and DSM-IV definition of hypochondriasis makes it rarely used yet does not prevent extensive diagnosis overlap. This study identified a distinct hypochondriasis symptom cluster and defined diagnostic criteria. METHOD: ...

https://doi.org/10.1176/appi.ajp.161.9.1680

Publication date: 01 September 2004

Pages1692–1697

OBJECTIVE: The authors aimed to evaluate the adequacy of the reporting of safety information in publications of randomized trials of mental-health-related interventions. METHOD: The authors randomly selected 200 entries from the PsiTri registry of mental-...

https://doi.org/10.1176/appi.ajp.161.9.1692

Brief Report

Publication date: 01 September 2004

Pages1698–1700

OBJECTIVE: Transmission of the brain-derived neurotrophic factor (BDNF) Val66 allele in children with a prepubertal and early adolescent bipolar disorder phenotype was examined. METHOD: The prepubertal and early adolescent bipolar disorder phenotype was ...

https://doi.org/10.1176/appi.ajp.161.9.1698

Publication date: 01 September 2004

Pages1703–1705

OBJECTIVE: The authors assessed the association between the catechol-O-methyltransferase (COMT) Val158Met polymorphism and scores on the phobic anxiety scale of the Crown-Crisp Experimental Index. METHOD: A total of 1,234 women completed the Crown-Crisp ...

https://doi.org/10.1176/appi.ajp.161.9.1703

Publication date: 01 September 2004

Pages1705–1708

OBJECTIVE: Because glutamate carboxypeptidase II (GCPII) regulates both folate absorption and activation of N-methyl-d-aspartic acid receptors, the authors examined relationships between serum folate concentrations and clinical symptoms in schizophrenia ...

https://doi.org/10.1176/appi.ajp.161.9.1705

Publication date: 01 September 2004

Pages1709–1711

OBJECTIVE: The purpose of the study was to determine the proportion of patients with schizophrenia with a stable regimen of antipsychotic monotherapy who developed diabetes or were hospitalized for ketoacidosis. METHOD: Patients with schizophrenia for ...

https://doi.org/10.1176/appi.ajp.161.9.1709

Publication date: 01 September 2004

Pages1712–1714

OBJECTIVE: Lack of insight affects the management of schizophrenia. The interrelationship between lack of insight and illness attributes in patients with schizophrenia who commit violent acts is important and underresearched. METHOD: One hundred fifteen ...

https://doi.org/10.1176/appi.ajp.161.9.1712

Letter to the Editor

Book Forum: Mental Health Care and Diagnosis

Book Forum: Neurology

Book Forum: Anxiety/Stress

Book Forum: Women’s Health…and Disorders

Book Forum: Forensic Psychiatry

Book Forum: History

APA Official Actions

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