American Journal of Psychiatry
- Volume 167
- Number 12
- December 2010
In This Issue
Perspectives
Editorials
Perspectives
Introspection
Perspectives
Clinical Case Conference
Perspectives
Reviews and Overviews
Publication date: 01 December 2010
Pages1445–1455Objective: Response to specific depression treatments varies widely among individuals. Understanding and predicting that variation could have great benefits for people living with depression. Method: The authors describe a conceptual model for identifying ...
https://doi.org/10.1176/appi.ajp.2010.09111680New Research
Articles
Publication date: 01 December 2010
Pages1456–1463Objective: The authors investigated recent trends in the use of outpatient psychotherapy in the United States. Method: Service use data from two representative surveys of the U.S. general population, the 1998 (N=22,953) and 2007 (N=29,370) Medical ...
https://doi.org/10.1176/appi.ajp.2010.10040570Publication date: 01 December 2010
Pages1464–1471Objective: Previous studies have shown that exposure to parental verbal abuse in childhood is associated with higher rates of adult psychopathology and alterations in brain structure. In this study the authors sought to examine the symptomatic and ...
https://doi.org/10.1176/appi.ajp.2010.10010030Publication date: 01 December 2010
Pages1472–1478Objective: Psychiatric researchers rely heavily on patient report data for clinical research. However, patient reports are prone to defensive and self-presentation biases. Recent research using practice networks has relied on clinician reports, and both ...
https://doi.org/10.1176/appi.ajp.2010.09101489Publication date: 01 December 2010
Pages1479–1488Objective: The onset of schizophrenia symptoms in late adolescence implies a neurodevelopmental trajectory for the disease. Indeed, the γ-aminobutyric acid (GABA) inhibitory system shows protracted development, and GABA-ergic deficits are widely replicated ...
https://doi.org/10.1176/appi.ajp.2010.09060784Publication date: 01 December 2010
Pages1489–1498Objective: Certain cognitive deficits in individuals with schizophrenia have been linked to disturbed gamma-aminobutyric acid (GABA) and glutamate neurotrans-mission in the prefrontal cortex. Thus, it is important to understand how the mechanisms that ...
https://doi.org/10.1176/appi.ajp.2010.10030318Publication date: 01 December 2010
Pages1499–1507Objective: Family and twin studies suggest that liability for suicide attempts is heritable and distinct from mood disorder susceptibility. The authors therefore examined the association between common genomewide variation and lifetime suicide attempts. ...
https://doi.org/10.1176/appi.ajp.2010.10040541Publication date: 01 December 2010
Pages1508–1517Objective: Research is increasingly linking autism spectrum disorders and other neurodevelopmental disorders to synaptic abnormalities (“synaptopathies”). PSD-95 (postsynaptic density-95, DLG4) orchestrates protein-protein interactions at excitatory ...
https://doi.org/10.1176/appi.ajp.2010.10040484Publication date: 01 December 2010
Pages1518–1525Objective: Increasing evidence for the importance of several risk factors for anxiety disorders is beginning to point to the possibility of prevention. Early interventions targeting known risk for anxiety have rarely been evaluated. The authors evaluated ...
https://doi.org/10.1176/appi.ajp.2010.09111619Publication date: 01 December 2010
Pages1526–1532Objective: Little is known about the neural underpinnings of generalized social phobia, which is defined by a persistent heightened fear of social disapproval. Using event-related functional MRI (fMRI), the authors examined whether the intent of an event, ...
https://doi.org/10.1176/appi.ajp.2010.09121797Communications and Updates
Letters to the Editor
Communications and Updates
Book Forum
Communications and Updates
Books Received
Past Issues
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Vol. 181 | No. 12
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