American Journal of Psychiatry
- Volume 167
- Number 8
- August 2010
In This Issue
Editorial
Clinical Case Conference
Images in Psychiatry
Reviews and Overviews
Publication date: 01 August 2010
Pages899–914Objective Structural variations of DNA, such as copy number variations (CNVs), are recognized to contribute both to normal genomic variability and to risk for human diseases. For example, schizophrenia has an established connection with 22q11.2 deletions. ...
https://doi.org/10.1176/appi.ajp.2009.09071016Article
Publication date: 01 August 2010
Pages915–924Objective Posttraumatic stress disorder (PTSD) related to childhood abuse is associated with features of affect regulation and interpersonal disturbances that substantially contribute to impairment. Existing treatments do not address these problems or the ...
https://doi.org/10.1176/appi.ajp.2010.09081247Publication date: 01 August 2010
Pages925–933Objective Borderline personality disorder is characterized by a lack of effective regulation of emotional responses. The authors investigated the role of the endogenous opioid system and μ-opioid receptors in emotion regulation in borderline personality ...
https://doi.org/10.1176/appi.ajp.2010.09091348Publication date: 01 August 2010
Pages934–941Objective Rapid discontinuation of some psychotropic medications is followed by discontinuation symptoms as well as an increased risk of early illness recurrence. Recurrence occurs earlier after rapid than after gradual discontinuation with lithium and ...
https://doi.org/10.1176/appi.ajp.2010.09060880Publication date: 01 August 2010
Pages942–948Objective Despite the progressive increase in the number of antidepressants, many patients with major depressive disorder continue to be symptomatic. Clearly, there is an urgent need to develop better tolerated and more effective treatments for this ...
https://doi.org/10.1176/appi.ajp.2009.09081198Publication date: 01 August 2010
Pages949–957Objective Studies of major depression in twins and families have shown moderate to high heritability, but extensive molecular studies have failed to identify susceptibility genes convincingly. To detect genetic variants contributing to major depression, ...
https://doi.org/10.1176/appi.ajp.2010.09091380Publication date: 01 August 2010
Pages958–968Objective The authors investigated the efficacy of a 12-week manualized meta-cognitive therapy group intervention designed to enhance time management, organization, and planning in adults with attention deficit hyperactivity disorder (ADHD). Method Eighty-...
https://doi.org/10.1176/appi.ajp.2009.09081123Publication date: 01 August 2010
Pages969–976Objective The course of alcohol disorders in women is often described as "telescoped" compared to that in men, with a later age at initiation of alcohol use but shorter times from use to dependence and treatment. This study examined evidence for such a ...
https://doi.org/10.1176/appi.ajp.2009.09081161Publication date: 01 August 2010
Pages977–986Objective Disturbances in the basal ganglia portions of cortico-striato-thalamo-cortical circuits likely contribute to the symptoms of attention deficit hyperactivity disorder (ADHD). The authors examined the morphologic features of the basal ganglia ...
https://doi.org/10.1176/appi.ajp.2010.09091259Publication date: 01 August 2010
Pages987–993Objective The authors examined the relationship between cannabis use and the course of illness in schizophrenia over 10 years of follow-up after first psychiatric hospitalization. Method The authors assessed 229 patients with a schizophrenia spectrum ...
https://doi.org/10.1176/appi.ajp.2010.09020189Letter to the Editor
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