American Journal of Psychiatry
- Volume 168
- Number 3
- March 2011
In This Issue
Perspectives
Editorials
Perspectives
Introspection
Perspectives
Clinical Case Conference
Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 March 2011
Pages253–256Ten years ago it was widely expected that the genetic basis of common disease would be resolved by genome-wide association studies (GWAS), large-scale studies in which the entire genome is covered by genetic markers. However, the bulk of heritable ...
https://doi.org/10.1176/appi.ajp.2010.10091340New Research
Articles
Publication date: 01 March 2011
Pages257–264Objective: The purpose of this study was to examine the effects of specific personality disorder comorbidity on the course of major depressive disorder in a nationally representative sample. Method: Data were drawn from 1,996 participants in a national ...
https://doi.org/10.1176/appi.ajp.2010.10050695Publication date: 01 March 2011
Pages265–275Objective: Severe drinking can cause serious morbidity and death. Because the serotonin transporter (5-HTT) is an important regulator of neuronal 5-HT function, allelic differences at that gene may modulate the severity of alcohol consumption and predict ...
https://doi.org/10.1176/appi.ajp.2010.10050755Publication date: 01 March 2011
Pages276–285Objective: Despite schizophrenia patients' reports of diminished experience of emotion in interviews and self-report measures, their emotional experience in the presence of emotional stimuli and in daily life (“in the moment”) appears largely intact. To ...
https://doi.org/10.1176/appi.ajp.2010.09081215Publication date: 01 March 2011
Pages286–292Objective: This study examined the effect of medication nonadherence on the return of positive symptoms among recent-onset schizophrenia patients. Method: Three sets of operational criteria for medication nonadherence with differing levels of severity were ...
https://doi.org/10.1176/appi.ajp.2010.09010087Publication date: 01 March 2011
Pages293–301Objective: Reduced amygdala activation in individuals with schizophrenia is thought to contribute to impairments in emotion recognition and social functioning. Recent work, however, suggests that amygdala abnormalities in schizophrenia are more nuanced ...
https://doi.org/10.1176/appi.ajp.2010.10060832Publication date: 01 March 2011
Pages302–316Objective: To evaluate previously reported associations of copy number variants (CNVs) with schizophrenia and to identify additional associations, the authors analyzed CNVs in the Molecular Genetics of Schizophrenia study (MGS) and additional available ...
https://doi.org/10.1176/appi.ajp.2010.10060876Publication date: 01 March 2011
Pages317–324Objective: Hyperactivity in frontal-striatal circuits is assumed to be involved in the pathophysiology of obsessive-compulsive disorder (OCD). In line with that, electrocortical correlates of overactive performance monitoring have been found to be ...
https://doi.org/10.1176/appi.ajp.2010.10030416Communications and Updates
Letters to the Editor
Communications and Updates
Book Forum
Communications and Updates
Books Received
Past Issues
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