American Journal of Psychiatry
- Volume 168
- Number 2
- February 2011
In This Issue
Perspectives
Editorials
Perspectives
Images in Psychiatry
Perspectives
Education in Psychiatry
Perspectives - Mechanisms of Psychiatric Illness
Reviews and Overviews
Severe Mood Dysregulation, Irritability, and the Diagnostic Boundaries of Bipolar Disorder in Youths
Publication date: 01 February 2011
Pages129–142In recent years, increasing numbers of children have been diagnosed with bipolar disorder. In some cases, children with unstable mood clearly meet current diagnostic criteria for bipolar disorder, and in others, the diagnosis is unclear. Severe mood ...
https://doi.org/10.1176/appi.ajp.2010.10050766New Research
Articles
Publication date: 01 February 2011
Pages143–151Objective: There is considerable epidemiological and neuropsychological evidence that attention deficit hyperactivity disorder (ADHD) is best considered dimensionally, lying at the extreme end of a continuous distribution of symptoms and underlying ...
https://doi.org/10.1176/appi.ajp.2010.10030385Publication date: 01 February 2011
Pages152–162Objective: Dysfunction in the amygdala and orbitofrontal cortex has been reported in youths and adults with psychopathic traits. The specific nature of the functional irregularities within these structures remains poorly understood. The authors used a ...
https://doi.org/10.1176/appi.ajp.2010.10010129Publication date: 01 February 2011
Pages163–172Objective: Despite increasing awareness of the many important roles played by brain-derived neurotrophic factor (BDNF) activation of TrkB, a fuller understanding of this system and the use of potential TrkB-acting therapeutic agents has been limited by the ...
https://doi.org/10.1176/appi.ajp.2010.10030326Publication date: 01 February 2011
Pages173–182Objective: The authors sought to better understand the neural circuitry associated with working memory deficits in psychotic major depression by examining brain function during an N-back task. Method: Study subjects were 16 patients with psychotic major ...
https://doi.org/10.1176/appi.ajp.2010.09121718Publication date: 01 February 2011
Pages183–192Objective: Alcoholism is associated with gray matter volume deficits in frontal and other brain regions. Whether persistent brain volume deficits in abstinence are predictive of subsequent time to alcohol relapse has not been established. The authors ...
https://doi.org/10.1176/appi.ajp.2010.10020233Publication date: 01 February 2011
Pages193–201Objective: The authors compared 1-year mortality rates associated with ziprasidone and olanzapine in real-world use. Method: The Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC) was an open-label, randomized, postmarketing large simple trial ...
https://doi.org/10.1176/appi.ajp.2010.08040484Publication date: 01 February 2011
Pages202–209Objective: Despite evidence demonstrating elevated comorbidity between schizophrenia and substance use disorders, the underlying mechanisms of association remain poorly understood. The brief time intervals that characterize interactions between substance ...
https://doi.org/10.1176/appi.ajp.2010.10030463Communications and Updates
Letters to the Editor
Communications and Updates
Correction
Communications and Updates
Book Forum
Communications and Updates
Books Received
Other Items of Interest
Past Issues
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