American Journal of Psychiatry
- Volume 169
- Number 10
- October 2012
In This Issue
Perspectives
Editorials
Perspectives
Presidential Addresses
Perspectives
Treatment in Psychiatry
Publication date: 01 October 2012
Pages1031–1036Standard treatments for bulimia nervosa are for patients with normal weight, but a growing proportion of patients are substantially overweight or obese. Weight-related medical problems require coordination with primary care and expanded treatment goals. ...
https://doi.org/10.1176/appi.ajp.2012.12010147Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 October 2012
Pages1038–1055Objective The authors performed a comprehensive meta-analysis of task-based functional MRI studies of attention deficit hyperactivity disorder (ADHD). Method The authors searched PubMed, Ovid, EMBASE, Web of Science, ERIC, CINAHAL, and NeuroSynth for studies ...
https://doi.org/10.1176/appi.ajp.2012.11101521New Research
Articles
Publication date: 01 October 2012
Pages1056–1064Applying the latest proposed DSM-5 criteria for autism spectrum disorder (ASD) to parent-reported symptoms yielded an ASD diagnosis for 91% of 4,453 children previously given DSM-IV clinical diagnoses of pervasive developmental disorders (PDDs)—autistic ...
https://doi.org/10.1176/appi.ajp.2012.12020276Publication date: 01 October 2012
Pages1065–1072Coexisting general medical illness accounts for much of the previously reported association between use of nonsteroidal anti-inflammatory drugs (NSAIDs) and nonremission of treated depression. A modest but smaller relationship for NSAIDs remained when ...
https://doi.org/10.1176/appi.ajp.2012.11091325Publication date: 01 October 2012
Pages1073–1081Objective Cross-sectional studies have demonstrated high rates of comorbidity among substance use disorders. However, few studies have examined the developmental course of incident comorbidity and how it changes from adolescence to adulthood. The authors ...
https://doi.org/10.1176/appi.ajp.2012.11081268Publication date: 01 October 2012
Pages1082–1091Objective In schizophrenia, alterations within the prefrontal cortical GABA system appear to be most prominent in neurons that contain parvalbumin or somatostatin but not calretinin. The transcription factors Lhx6 and Sox6 play critical roles in the ...
https://doi.org/10.1176/appi.ajp.2012.12030305Publication date: 01 October 2012
Pages1092–1099Objective The thalamus and cerebral cortex are connected via topographically organized, reciprocal connections. Previous studies have revealed thalamic abnormalities in schizophrenia; however, it is not known whether thalamocortical networks are ...
https://doi.org/10.1176/appi.ajp.2012.12010056Publication date: 01 October 2012
Pages1100–1108Objective Endophenotype studies of obsessive-compulsive disorder (OCD) may uncover heritable traits that are related to genetic susceptibility to OCD. Deficient response inhibition is a promising endophenotype of OCD, although its functional neural ...
https://doi.org/10.1176/appi.ajp.2012.12010073Publication date: 01 October 2012
Pages1109–1116Objective In children with conduct problems, high levels of callous-unemotional traits are associated with amygdala hypoactivity to consciously perceived fear, while low levels of callous-unemotional traits may be associated with amygdala hyperactivity. ...
https://doi.org/10.1176/appi.ajp.2012.12020191