American Journal of Psychiatry
- Volume 178
- Number 5
- May 2021
Editor's Note
Editorials
Commentary
Special Article
Publication date: 17 March 2021
Pages383–399Replicated international studies have underscored the human and societal costs associated with major depressive disorder. Despite the proven efficacy of monoamine-based antidepressants in major depression, the majority of treated individuals fail to ...
https://doi.org/10.1176/appi.ajp.2020.20081251Reviews and Overviews
Publication date: 03 March 2021
Pages400–413Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique uniquely equipped to both examine and modulate neural systems and related cognitive and behavioral functions in humans. As an examination tool, TMS can be used in ...
https://doi.org/10.1176/appi.ajp.2020.20071050Articles
Publication date: 29 October 2020
Pages414–423Objective: Clinical practice guidelines recommend concurrent treatment of co-occurring depression and substance use disorders; however, the degree to which patients with substance use disorders receive guideline-concordant treatment for depression is ...
https://doi.org/10.1176/appi.ajp.2020.20040454Publication date: 18 February 2021
Pages424–436Objective: This study compared relapse prevention and acceptability of long-acting injectable (LAI) antipsychotics in the maintenance treatment of adults with nonaffective psychoses. Methods: The authors searched MEDLINE, Embase, PsycINFO, CINAHL, ...
https://doi.org/10.1176/appi.ajp.2020.20071120Publication date: 03 March 2021
Pages437–446Objective: Preclinical studies point to the KCNQ2/3 potassium channel as a novel target for the treatment of depression and anhedonia, a reduced ability to experience pleasure. The authors conducted the first randomized placebo-controlled trial testing ...
https://doi.org/10.1176/appi.ajp.2020.20050653Publication date: 19 November 2020
Pages447–458Objective: Alcohol use disorder (AUD) is a leading cause of global disease burden. Chronic, heavy use increases the likelihood of alcohol withdrawal symptoms and associated secondary outcomes of alcohol craving and mood, anxiety, and sleep disturbances, ...
https://doi.org/10.1176/appi.ajp.2020.20050609Publication date: 17 March 2021
Pages459–468Objective: Compulsive behaviors are a core feature of obsessive-compulsive spectrum disorders but appear across a broad spectrum of psychological conditions. It is thought that compulsions reflect a failure to override habitual behaviors “stamped in” ...
https://doi.org/10.1176/appi.ajp.2020.20060821Letters to the Editor
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