The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 17
- Number 3
- August 2005
Windows to the Brain
Editorial
Special Article
Publication date: 01 August 2005
Pages310–323Parkinson’s disease (PD) is a progressive neurological condition with debilitating symptoms, and depression is a common comorbid condition of this disease. The authors review existing literature on the prevalence and treatment of depression in PD. ...
https://doi.org/10.1176/jnp.17.3.310Publication date: 01 August 2005
Pages324–332Most clinical trials in Tourette’s syndrome (TS) involve fewer than 60 patients. This is partially due to difficulties recruiting patients who have multiple neuropsychiatric diagnoses. Few studies permit treatment of comorbid diagnoses or compare active ...
https://doi.org/10.1176/jnp.17.3.324Commentary
Regular Article
Publication date: 01 August 2005
Pages336–341The authors assessed long-term changes in autobiographical and public remote memory in a series of 21 patients with Alzheimer’s disease (AD) and 10 age-comparable healthy comparison subjects who underwent two evaluations, with an interval ranging from 24 ...
https://doi.org/10.1176/jnp.17.3.336Publication date: 01 August 2005
Pages342–349Apathy is common in Alzheimer’s disease (AD) but may be confused with depression due to overlap in symptoms queried in depression assessments. Depression and dysphoria appear to occur less frequently in AD but are better researched. This study examined ...
https://doi.org/10.1176/jnp.17.3.342Publication date: 01 August 2005
Pages350–356This study evaluated the prevalence and specificity of diagnostic criteria for postconcussional syndrome (PCS) in 178 adults with mild to moderate traumatic brain injury (TBI) and 104 with extracranial trauma. Diagnostic and Statistical Manual of Mental ...
https://doi.org/10.1176/jnp.17.3.350Publication date: 01 August 2005
Pages357–363In vivo proton magnetic resonance spectroscopy (1H-MRS) has been used to assess biochemical changes that occur in demyelinating lesions and in normal appearing white matter (NAWM) in multiple sclerosis (MS) patients. N-acetylaspartate (NAA) levels in MS ...
https://doi.org/10.1176/jnp.17.3.357Publication date: 01 August 2005
Pages364–371Corticobasal degeneration (CBD) is an adult-onset progressive neurodegenerative disorder. However, its pathogenic mechanisms underlying this disorder remain poorly understood. The authors examined changes of proteome profiles between three nondemented ...
https://doi.org/10.1176/jnp.17.3.364Publication date: 01 August 2005
Pages372–377Increasing evidence suggests that the steroid hormone testosterone (T) enhances libido and decreases depression. Even a single administration of T (0.5 mg sublingually) in healthy young women is sufficient to enhance physiological sexual responsiveness. ...
https://doi.org/10.1176/jnp.17.3.372Publication date: 01 August 2005
Pages378–383The natural history of psychiatric syndromes associated with Huntington’s disease (HD) remains unclear, and longitudinal studies of symptoms such as depression, apathy, and irritability are required to better understand the progression and role of these ...
https://doi.org/10.1176/jnp.17.3.378Publication date: 01 August 2005
Pages384–390Schizophrenia is a heterogeneous disorder. The syndrome and the symptom-oriented approaches are two methods that have been used to examine differences in psychopathological processes across different patients with schizophrenia. The authors indirectly ...
https://doi.org/10.1176/jnp.17.3.384Publication date: 01 August 2005
Pages391–398Sustained attention and working memory (WM) are closely related functions that may share common mechanisms. The authors assessed sustained attention in schizophrenia patients and healthy comparison subjects using visuomotor tracking tasks under varying ...
https://doi.org/10.1176/jnp.17.3.391Publication date: 01 August 2005
Pages399–404Obsessive-compulsive symptoms have been associated with different types of damages or dysfunctions in the brain. However, the accumulated evidence on obsessive-compulsive symptoms among patients with a primary brain tumor is so far based on case reports ...
https://doi.org/10.1176/jnp.17.3.399Publication date: 01 August 2005
Pages405–412Excessive sleepiness associated with narcolepsy lasts throughout the waking day. The authors conducted two randomized, double-blind studies to compare the efficacy of modafinil once-daily versus split doses in maintaining wakefulness throughout the day. ...
https://doi.org/10.1176/jnp.17.3.405Clinical and Research Reports
Publication date: 01 August 2005
Pages413–416Loss of insight is a diagnostic criterion for frontotemporal dementia. It is associated with hypoperfusion/hypometabolism in the right hemisphere, particularly the frontal lobe. Loss of insight is often an anosodiaphoria (i.e., lack of concern) rather ...
https://doi.org/10.1176/jnp.17.3.413Publication date: 01 August 2005
Pages417–420Twenty one patients in a residential rehabilitation program fulfilling International Classification of Diseases-10 (ICD) criteria for alcohol dependence syndrome were recruited. On neuropsychological tests, alcohol dependent patients relapsed early if ...
https://doi.org/10.1176/jnp.17.3.417Publication date: 01 August 2005
Pages421–422Aripiprazole is an agent for treating schizophrenia. The authors assume that aripiprazole as a dopamine receptor partial agonist may be useful in treating PD patients. Three cases are presented in this study. All patients were evaluated by the same ...
https://doi.org/10.1176/jnp.17.3.421Publication date: 01 August 2005
Pages423–424The authors report findings from an 8-week, open-label trial conducted to evaluate efficacy of olanzapine in treating negative symptoms in Alzheimer’s disease (AD). Subjects were AD patients age 50 and older who exhibited untreated neuropsychiatric ...
https://doi.org/10.1176/jnp.17.3.423Book Reviews
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