American Journal of Psychiatry
- Volume 168
- Number 10
- October 2011
In This Issue
Perspectives
Editorial
Perspectives
APA Presidential Addresses
Perspectives
Introspection
Perspectives
Images in Psychiatry
Perspectives
Treatment in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 October 2011
Pages1041–1049Research on how interactions between candidate genes and environmental factors influence psychiatric illnesses has generated enthusiasm but not many replicable findings. The authors discovered that the more closely a replication study matched the original ...
https://doi.org/10.1176/appi.ajp.2011.11020191New Research
Articles
Publication date: 01 October 2011
Pages1050–1056A 2.5-year randomized trial of lithium versus valproate treatment for patients with bipolar disorder who had made a previous suicide attempt found no difference in subsequent attempts between the two treatment groups.
https://doi.org/10.1176/appi.ajp.2011.11010163Publication date: 01 October 2011
Pages1057–1065Prescription of antipsychotic medications during visits for anxiety disorders doubled between 1996 and 2007 among office-based psychiatrists, from 10.6% to 21.3% of visits. The nationwide data demonstrate increases for comorbid FDA-approved indications, ...
https://doi.org/10.1176/appi.ajp.2011.11010087Publication date: 01 October 2011
Pages1066–1074Depression scores declined more for depressed patients with Parkinson's disease who received 10 weeks of CBT plus clinical monitoring than for those who received clinical monitoring only. The study of 80 patients also showed greater improvements in ...
https://doi.org/10.1176/appi.ajp.2011.10111669Publication date: 01 October 2011
Pages1075–1082Brain activation differences during emotional processing between elderly patients with and without major depressive disorder were greater for depressed patients with more white matter lesions.
https://doi.org/10.1176/appi.ajp.2011.10060853Publication date: 01 October 2011
Pages1083–1089Variants in SORL1 have previously been established to increase the risk for Alzheimer's disease. The findings from this study that multiple variants in SORL1 contributed to decreased hippocampal size suggest a biological basis for this effect and thus ...
https://doi.org/10.1176/appi.ajp.2011.10101509Effects of the Circadian Rhythm Gene Period 1 (Per1) on Psychosocial Stress-Induced Alcohol Drinking
Publication date: 01 October 2011
Pages1090–1098Converging evidence from an animal model, two human populations (one at risk and the other with confirmed alcoholism), and molecular studies on the human gene itself has provided a chain of support for the hypothesis of a role for the Per1 gene and its ...
https://doi.org/10.1176/appi.ajp.2011.10111579Publication date: 01 October 2011
Pages1099–1106Since ADHD and, in particular, impulsivity are related to decreased ventral striatal activity, it was hypothesized that the NOS1 genotype itself might also be related to decreased ventral striatal activity. However, the authors found instead that NOS1 ...
https://doi.org/10.1176/appi.ajp.2011.10101446Publication date: 01 October 2011
Pages1107–1116The FKBP5 gene modulates function of glucocorticoid receptors and has been frequently studied as a risk factor for depression and suicidality. This long-term study found a gene-by-environment effect for minor variants in the gene in the presence of trauma ...
https://doi.org/10.1176/appi.ajp.2011.10111577