American Journal of Psychiatry
- Volume 178
- Number 1
- January 2021
Editor’s Note
Editorials
Reviews and Overviews
Publication date: 01 January 2021
Pages17–29Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling disorder. The only established first-line treatments for OCD are exposure and response prevention, and serotonin reuptake inhibitor medications (SRIs). However, a subset of ...
https://doi.org/10.1176/appi.ajp.2020.20111601Publication date: 01 January 2021
Pages30–38Recent progress in the identification of genes and genomic regions contributing to autism spectrum disorder (ASD) has had a broad impact on our understanding of the nature of genetic risk for a range of psychiatric disorders, on our understanding of ASD ...
https://doi.org/10.1176/appi.ajp.2020.20111608Articles
Publication date: 28 August 2020
Pages39–47Objective: The authors sought to examine whether brain activity is associated with treatment response to cognitive-behavioral therapy (CBT) in adolescents and adults with obsessive-compulsive disorder (OCD), and whether any associations are treatment ...
https://doi.org/10.1176/appi.ajp.2020.19080886Publication date: 16 June 2020
Pages48–64Objective: Pediatric obsessive-compulsive disorder (OCD) sometimes appears rapidly, even overnight, often after an infection. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, or PANDAS, describes such a situation ...
https://doi.org/10.1176/appi.ajp.2020.19070698Publication date: 16 June 2020
Pages65–76Objective: Psychiatric disorders commonly comprise comorbid symptoms, such as autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD), raising controversies over accurate diagnosis and ...
https://doi.org/10.1176/appi.ajp.2020.19101091Publication date: 01 January 2021
Pages77–86Objective: Certain copy number variants (CNVs) greatly increase the risk of autism. The authors conducted a genetics-first study to investigate whether heterogeneity in the clinical presentation of autism is underpinned by specific genotype-phenotype ...
https://doi.org/10.1176/appi.ajp.2020.20010015Publication date: 11 September 2020
Pages87–98Objective: Deleterious copy number variants (CNVs) are identified in up to 20% of individuals with autism. However, levels of autism risk conferred by most rare CNVs remain unknown. The authors recently developed statistical models to estimate the effect ...
https://doi.org/10.1176/appi.ajp.2020.19080834