American Journal of Psychiatry
- Volume 177
- Number 12
- December 2020
Editor’s Note
Editorials
Commentaries
Reviews and Overviews
Articles
Publication date: 01 December 2020
Pages1129–1139Objective:Altering the metabotropic glutamate receptor 3 (mGluR3) by pharmacology or genetics is associated with differences in learning and memory in animals and humans. GRM3 (the gene coding for mGluR3) is also genome-wide associated with risk for ...
https://doi.org/10.1176/appi.ajp.2020.19111152Publication date: 29 October 2020
Pages1140–1150Objective:The shared risk factors and clinical features in schizophrenia and bipolar disorder may be linked via mitochondrial dysfunction. However, the severity of mitochondrial dysfunction, and/or the specific mitochondrial functional pathways affected, ...
https://doi.org/10.1176/appi.ajp.2020.19111210Publication date: 27 May 2020
Pages1151–1158Objective:Conceptualizations of delusion formation implicate deficits in feedforward information updating across the posterior to prefrontal cortices, resulting in dysfunctional integration of new information about contexts in working memory and, ...
https://doi.org/10.1176/appi.ajp.2020.19111176Publication date: 11 September 2020
Pages1159–1167Objective:Thalamus models of psychosis implicate association nuclei in the pathogenesis of psychosis and mechanisms of cognitive impairment. Studies to date have provided conflicting findings for structural deficits specific to these nuclei. The authors ...
https://doi.org/10.1176/appi.ajp.2020.19101099Publication date: 14 August 2020
Pages1168–1178Objective:A combination of olanzapine and the opioid receptor antagonist samidorphan is under development for the treatment of schizophrenia and bipolar I disorder. The single-tablet combination treatment is intended to provide the efficacy of olanzapine ...
https://doi.org/10.1176/appi.ajp.2020.19121279Letters to the Editor
Appreciation
Publication date: 01 December 2020
Pages1187–1190https://doi.org/10.1176/appi.ajp.2020.17712reviewersPast Issues
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