The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 15
- Number 1
- February 2003
Windows to the Brain
Special Article
Publication date: 01 February 2003
Pages7–16The aim of this study was to investigate the first changes in cognitive and motor functioning in Huntington's disease. Forty-six gene carriers, not clinically diagnosed for HD, were compared with 88 non–gene carriers. Gene carriers performed significantly ...
https://doi.org/10.1176/jnp.15.1.7Publication date: 01 February 2003
Pages17–26Although traumatic brain injury (TBI) frequently results in significant handicap, empirical investigations of pharmacological treatment of the neurobehavioral sequelae of TBI are rare. This review presents evidence that supports hypotheses of a ...
https://doi.org/10.1176/jnp.15.1.17Regular Article
Publication date: 01 February 2003
Pages27–34The authors retrospectively compared the seizure duration, ictal EEG, and cognitive side effects of ketamine and methohexital anesthesia with ECT. This comparison was carried out with data from consecutive index ECT treatments that occurred immediately ...
https://doi.org/10.1176/jnp.15.1.27Publication date: 01 February 2003
Pages35–44This study examined regional cerebral blood flow (rCBF) changes associated with visually induced sad affect in healthy elderly persons. Subjects viewed sadness-laden, happiness-laden, and emotionally neutral image sets while rCBF was recorded using [15O] ...
https://doi.org/10.1176/jnp.15.1.35Publication date: 01 February 2003
Pages45–52Some investigators assert that emergence of schizophrenia spectrum disorders in mid- to late life (LOSD, i.e., onset after age 45) reflects neurodegenerative processes. The authors examined 1- and 2-year changes among 37 outpatients with LOSDs on the Mini-...
https://doi.org/10.1176/jnp.15.1.45Publication date: 01 February 2003
Pages53–57The authors obtained a frontal functions profile for 81 schizophrenic patients using six neuropsychological tests that evaluate the dorsolateral prefrontal cortex functions, i.e., working memory, executive functions, and strategic performance. They then ...
https://doi.org/10.1176/jnp.15.1.53Publication date: 01 February 2003
Pages58–63This study investigated whether drug-naive patients with schizophrenia present procedural learning disturbances, given that this function is known to involve the striatum and that structural abnormalities of the striatum have been described in these ...
https://doi.org/10.1176/jnp.15.1.58Publication date: 01 February 2003
Pages64–66This study takes into consideration whether low serum folate levels may contribute to depressive mood in patients with chronic epilepsy. The serum folate levels and the score on the Self-Rating Depression Scale (SDS) were examined in 46 patients with ...
https://doi.org/10.1176/jnp.15.1.64Publication date: 01 February 2003
Pages67–73The authors examined the pattern of use of psychiatric medication as prescribed by community physicians in 1,155 patients with probable Alzheimer's disease (AD) referred to the Alzheimer's Disease Research Center of Pittsburgh between April 1983 and July ...
https://doi.org/10.1176/jnp.15.1.67Publication date: 01 February 2003
Pages74–77This study assessed the sensitivity of individual depressive symptoms and their relative contribution to the diagnosis of depressive disorder in patients with Parkinson's disease. The Structured Clinical Interview for DSM-IV Depression and the Hamilton ...
https://doi.org/10.1176/jnp.15.1.74Publication date: 01 February 2003
Pages78–83It is still unclear whether apolipoprotein E epsilon 4 (APOE E4) influences the cerebral glucose metabolism abnormalities found in Alzheimer's disease (AD), although APOE E4 is a well-known risk factor for AD. [18F]Fluorodeoxyglucose PET was conducted in ...
https://doi.org/10.1176/jnp.15.1.78Publication date: 01 February 2003
Pages84–89This study assessed cognitive deficit in patients diagnosed with different stages of hepatic cirrhosis and in liver transplant recipients. A short protocol consisting of several psychometric tests was used. Cirrhotic patients showed a degree of mental ...
https://doi.org/10.1176/jnp.15.1.84Publication date: 01 February 2003
Pages90–97The authors evaluated the late neurocognitive profile and progress of memory functions in 60 patients with primary nasopharyngeal carcinoma who had been treated with radiation therapy for more than 2 years. Forty had imaging evidence of temporal lobe ...
https://doi.org/10.1176/jnp.15.1.90Publication date: 01 February 2003
Pages98–104People with depression report frequent cognitive failures, but objective measures of cognition show mixed results. Some studies show impairment on effortful tasks. The relationship between subjective and objective cognitive failures was studied in 102 “...
https://doi.org/10.1176/jnp.15.1.98Clinical and Research Reports
Publication date: 01 February 2003
Pages105–107The authors measured odor detection threshold and odor identification in 12 males with Asperger's syndrome and 12 matched control subjects. Relative to control subjects, Asperger's syndrome subjects were not impaired at odor detection but were ...
https://doi.org/10.1176/jnp.15.1.105