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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 15
  • Number 1
  • February 2003

Windows to the Brain

Special Article

Publication date: 01 February 2003

Pages7–16

The aim of this study was to investigate the first changes in cognitive and motor functioning in Huntington's disease. Forty-six gene carriers, not clinically diagnosed for HD, were compared with 88 non–gene carriers. Gene carriers performed significantly ...

https://doi.org/10.1176/jnp.15.1.7

Publication date: 01 February 2003

Pages17–26

Although traumatic brain injury (TBI) frequently results in significant handicap, empirical investigations of pharmacological treatment of the neurobehavioral sequelae of TBI are rare. This review presents evidence that supports hypotheses of a ...

https://doi.org/10.1176/jnp.15.1.17

Regular Article

Publication date: 01 February 2003

Pages27–34

The authors retrospectively compared the seizure duration, ictal EEG, and cognitive side effects of ketamine and methohexital anesthesia with ECT. This comparison was carried out with data from consecutive index ECT treatments that occurred immediately ...

https://doi.org/10.1176/jnp.15.1.27

Publication date: 01 February 2003

Pages35–44

This study examined regional cerebral blood flow (rCBF) changes associated with visually induced sad affect in healthy elderly persons. Subjects viewed sadness-laden, happiness-laden, and emotionally neutral image sets while rCBF was recorded using [15O] ...

https://doi.org/10.1176/jnp.15.1.35

Publication date: 01 February 2003

Pages45–52

Some investigators assert that emergence of schizophrenia spectrum disorders in mid- to late life (LOSD, i.e., onset after age 45) reflects neurodegenerative processes. The authors examined 1- and 2-year changes among 37 outpatients with LOSDs on the Mini-...

https://doi.org/10.1176/jnp.15.1.45

Publication date: 01 February 2003

Pages53–57

The authors obtained a frontal functions profile for 81 schizophrenic patients using six neuropsychological tests that evaluate the dorsolateral prefrontal cortex functions, i.e., working memory, executive functions, and strategic performance. They then ...

https://doi.org/10.1176/jnp.15.1.53

Publication date: 01 February 2003

Pages58–63

This study investigated whether drug-naive patients with schizophrenia present procedural learning disturbances, given that this function is known to involve the striatum and that structural abnormalities of the striatum have been described in these ...

https://doi.org/10.1176/jnp.15.1.58

Publication date: 01 February 2003

Pages64–66

This study takes into consideration whether low serum folate levels may contribute to depressive mood in patients with chronic epilepsy. The serum folate levels and the score on the Self-Rating Depression Scale (SDS) were examined in 46 patients with ...

https://doi.org/10.1176/jnp.15.1.64

Publication date: 01 February 2003

Pages67–73

The authors examined the pattern of use of psychiatric medication as prescribed by community physicians in 1,155 patients with probable Alzheimer's disease (AD) referred to the Alzheimer's Disease Research Center of Pittsburgh between April 1983 and July ...

https://doi.org/10.1176/jnp.15.1.67

Publication date: 01 February 2003

Pages74–77

This study assessed the sensitivity of individual depressive symptoms and their relative contribution to the diagnosis of depressive disorder in patients with Parkinson's disease. The Structured Clinical Interview for DSM-IV Depression and the Hamilton ...

https://doi.org/10.1176/jnp.15.1.74

Publication date: 01 February 2003

Pages78–83

It is still unclear whether apolipoprotein E epsilon 4 (APOE E4) influences the cerebral glucose metabolism abnormalities found in Alzheimer's disease (AD), although APOE E4 is a well-known risk factor for AD. [18F]Fluorodeoxyglucose PET was conducted in ...

https://doi.org/10.1176/jnp.15.1.78

Publication date: 01 February 2003

Pages84–89

This study assessed cognitive deficit in patients diagnosed with different stages of hepatic cirrhosis and in liver transplant recipients. A short protocol consisting of several psychometric tests was used. Cirrhotic patients showed a degree of mental ...

https://doi.org/10.1176/jnp.15.1.84

Publication date: 01 February 2003

Pages90–97

The authors evaluated the late neurocognitive profile and progress of memory functions in 60 patients with primary nasopharyngeal carcinoma who had been treated with radiation therapy for more than 2 years. Forty had imaging evidence of temporal lobe ...

https://doi.org/10.1176/jnp.15.1.90

Publication date: 01 February 2003

Pages98–104

People with depression report frequent cognitive failures, but objective measures of cognition show mixed results. Some studies show impairment on effortful tasks. The relationship between subjective and objective cognitive failures was studied in 102 “...

https://doi.org/10.1176/jnp.15.1.98

Clinical and Research Reports

Publication date: 01 February 2003

Pages105–107

The authors measured odor detection threshold and odor identification in 12 males with Asperger's syndrome and 12 matched control subjects. Relative to control subjects, Asperger's syndrome subjects were not impaired at odor detection but were ...

https://doi.org/10.1176/jnp.15.1.105

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