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American Journal of Psychiatry

  • Volume 154
  • Number 12
  • December 1997

Editorial

Images in Neuroscience

Special Article

Publication date: 01 December 1997

Pages1641–1647

OBJECTIVE: The goal of this overview is to examine male/female differences in psychopathology in light of the known effects of gonadal steroids, especially estradiol, on neural function. METHOD: The epidemiology of specific psychopathological syndromes is ...

https://doi.org/10.1176/ajp.154.12.1641

Regular Article

Publication date: 01 December 1997

Pages1648–1654

OBJECTIVE: The current literature on sex differences in schizophrenia with regard to structural brain abnormalities is inconsistent. Several studies have suggested that male and female patients may differ in severity of brain abnormalities. Efforts to ...

https://doi.org/10.1176/ajp.154.12.1648

Publication date: 01 December 1997

Pages1655–1662

OBJECTIVE: Evidence supports abnormal temporal lobe structure and function in schizophrenia. Some abnormalities, particularly involving the auditory cortex, appear to be sex specific. These findings were extended to anatomical and physiological ...

https://doi.org/10.1176/ajp.154.12.1655

Publication date: 01 December 1997

Pages1663–1669

OBJECTIVE: Studies have suggested that the maldeveloped neural circuitry producing schizophrenic symptoms may include the cerebellum. The authors found further support for this hypothesis by examining cerebellar morphology in severely ill children and ...

https://doi.org/10.1176/ajp.154.12.1663

Publication date: 01 December 1997

Pages1670–1675

OBJECTIVE: Attentional deficits are a prominent aspect of cognitive dysfunction in schizophrenia. The anterior cingulate gyrus is proposed to be an important component of frontal attentional control systems. Structural and functional abnormalities have ...

https://doi.org/10.1176/ajp.154.12.1670

Publication date: 01 December 1997

Pages1683–1689

OBJECTIVE: After peaking during childhood, synaptic density in the human frontal cortex declines by 30%–40% during adolescence because of progressive elimination of synaptic connections. The characteristic age at onset of schizophrenia—late adolescence ...

https://doi.org/10.1176/ajp.154.12.1683

Publication date: 01 December 1997

Pages1696–1702

OBJECTIVE: This report describes a 1-year follow-up study of survivors of a mass shooting incident. Acute-phase data from this incident were previously reported in this journal. METHOD: The Diagnostic Interview Schedule/Disaster Supplement was used to ...

https://doi.org/10.1176/ajp.154.12.1696

Publication date: 01 December 1997

Pages1703–1710

OBJECTIVE: The skepticism regarding the existence of dissociative identity disorder as well as the abuse that engenders it persists for lack of objective documentation. This is doubly so for the disorder in murderers because of issues of suspected ...

https://doi.org/10.1176/ajp.154.12.1703

Publication date: 01 December 1997

Pages1711–1714

OBJECTIVE: Although seasonal variation in impulsive aggression related to circannual rhythms of central serotonin neurotransmission is a topic of current interest, there is little firm knowledge on seasonality in the occurrence of homicide. Longitudinal ...

https://doi.org/10.1176/ajp.154.12.1711

Publication date: 01 December 1997

Pages1715–1719

OBJECTIVE: This study examined the relationship between characteristics of borderline personality disorder and suicidal behavior. The authors hypothesized that a specific feature of borderline personality disorder, impulsivity, and childhood trauma, a ...

https://doi.org/10.1176/ajp.154.12.1715

Publication date: 01 December 1997

Pages1720–1725

OBJECTIVE: The authors sought to determine the HIV seroprevalence among suicide victims in New York City. METHOD: All suicides of city residents from 1991 through 1993 were studied. The crude proportion of all suicide victims who were HIV positive and the ...

https://doi.org/10.1176/ajp.154.12.1720

Publication date: 01 December 1997

Pages1734–1740

OBJECTIVE: This article examines social and occupational disability associated with several DSM-IV mental disorders in a group of adult primary care outpatients. METHOD: The subjects were 1,001 primary care patients (aged 18–70 years) in a large health ...

https://doi.org/10.1176/ajp.154.12.1734

Publication date: 01 December 1997

Pages1741–1746

OBJECTIVE: This study assessed cycle to cycle symptom stability in women with premenstrual syndrome (PMS). METHOD: Symptom ratings obtained prospectively over three or more symptomatic cycles from 16 women with PMS were analyzed. Measures of symptom ...

https://doi.org/10.1176/ajp.154.12.1741

Clinical Case Conference

Images in Psychiatry

Brief Report

Publication date: 01 December 1997

Pages1752–1756

OBJECTIVE: Preliminary studies have indicated that daily left prefrontal repetitive transcranial magnetic stimulation might have antidepressant activity. The authors sought to confirm this finding by using a double-blind crossover design. METHOD: Twelve ...

https://doi.org/10.1176/ajp.154.12.1752

Publication date: 01 December 1997

Pages1757–1759

OBJECTIVE: This prospective study assessed changes in depression and sexual functioning in chronically depressed men and women during treatment with selective serotonin reuptake inhibitors (SSRIs). METHOD: Twenty-five subjects (14 women, 11 men) with DSM-...

https://doi.org/10.1176/ajp.154.12.1757

Publication date: 01 December 1997

Pages1760–1762

OBJECTIVE: The rate of adverse events following discontinuation of treatment with extended-release venlafaxine was compared with the rate associated with discontinuation of placebo administration. METHOD: The subjects were 20 outpatients with major ...

https://doi.org/10.1176/ajp.154.12.1760

Publication date: 01 December 1997

Pages1763–1765

OBJECTIVE: Clozapine increases the levels of cytokines and soluble cytokine receptors. The authors investigated whether haloperidol has similar effects. METHOD: Rectal temperature, white blood cell counts, and plasma levels of cytokines and soluble ...

https://doi.org/10.1176/ajp.154.12.1763

Publication date: 01 December 1997

Pages1766–1768

OBJECTIVE: This study examined the effect of self-reported anxiety on the number of days persons with various general medical conditions spend in bed owing to disability. METHOD: Self-reported medical illness and disability data from a nationally ...

https://doi.org/10.1176/ajp.154.12.1766

Publication date: 01 December 1997

Pages1769–1770

OBJECTIVE: This study investigated the possible relationship between impulsivity in early adolescence and gambler status in late adolescence. METHOD: Impulsivity measures consisting of self-reports and teacher ratings were gathered from 754 boys in early ...

https://doi.org/10.1176/ajp.154.12.1769

Publication date: 01 December 1997

Pages1771–1773

OBJECTIVE: The relationship between genetic liability for antisocial behavior and CSF 5-hydroxyindoleacetic acid (5-HIAA) in newborns was explored. METHOD: The authors assayed 5-HIAA in “leftover” CSF from 193 neurologically normal newborns and obtained ...

https://doi.org/10.1176/ajp.154.12.1771

Book Forum

Letter to the Editor

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