American Journal of Psychiatry
- Volume 157
- Number 5
- May 2000
Editorial
Reviews and Overviews
Publication date: 01 May 2000
Pages669–682OBJECTIVE: Quality-of-life indices have been used in medical practice to estimate the impact of different diseases on functioning and well-being and to compare outcomes between different treatment modalities. An integrated view of the issue of quality of ...
https://doi.org/10.1176/appi.ajp.157.5.669Publication date: 01 May 2000
Pages683–694OBJECTIVE: This article reviews recent developments in cytokine biology that are relevant to clinical psychiatry.METHOD: The authors reviewed English-language literature of the last 15 years that pertains to the biology of cytokines with emphasis on ...
https://doi.org/10.1176/appi.ajp.157.5.683Images In Neuroscience
Clinical Case Conference
Images In Psychiatry
Article
Publication date: 01 May 2000
Pages704–707OBJECTIVE: This study investigated the prevalence of dementia in a general hospital, reasons for which patients with dementia were admitted, and the relationship between dementia and length of stay, cost, and in-hospital mortality rate. METHOD: The study ...
https://doi.org/10.1176/appi.ajp.157.5.704Publication date: 01 May 2000
Pages708–714OBJECTIVE: The authors report findings from a study of 5,092 community residents who constituted 90% of the elderly resident population of Cache County, Utah. METHOD: The 5,092 participants, who were 65 years old or older, were screened for dementia. ...
https://doi.org/10.1176/appi.ajp.157.5.708Publication date: 01 May 2000
Pages715–721OBJECTIVE: It has been hypothesized that adequate concentrations of vitamin B12 and folate are essential to maintain the integrity of the neurological systems involved in mood regulation, but epidemiologic evidence for such a link in the general ...
https://doi.org/10.1176/appi.ajp.157.5.715Publication date: 01 May 2000
Pages722–728OBJECTIVE: Anxiety disorders are common in adults with depressive disorders, but several studies have suggested a relatively low prevalence of anxiety disorders in older individuals with depression. This cross-sectional study measured current and lifetime ...
https://doi.org/10.1176/appi.ajp.157.5.722Publication date: 01 May 2000
Pages729–736OBJECTIVE: This study was designed to evaluate the comparative efficacy and safety of sertraline and nortriptyline for the treatment of major depressive disorder in older adults. METHOD: A double-blind, parallel group design was used to compare 210 ...
https://doi.org/10.1176/appi.ajp.157.5.729Publication date: 01 May 2000
Pages737–744OBJECTIVE: Alcohol use disorders (defined as DSM-IV alcohol dependence or abuse) are prevalent and serious problems among adolescents. As adolescence is marked by progressive hippocampal development, this brain region may be particularly susceptible to ...
https://doi.org/10.1176/appi.ajp.157.5.737Publication date: 01 May 2000
Pages745–750OBJECTIVE: This study aimed to describe the natural course of DSM-III-R alcohol disorders as a function of age at first alcohol use and to investigate the influence of early use as a risk factor for progression to the development of alcohol disorders, ...
https://doi.org/10.1176/appi.ajp.157.5.745Publication date: 01 May 2000
Pages751–758OBJECTIVE: The authors’ goal was to determine whether depression is associated with a greater risk of heavy alcohol consumption in women. METHOD: The study was based on a 1-year follow-up of the Baltimore cohort of the National Institute of Mental Health ...
https://doi.org/10.1176/appi.ajp.157.5.751Publication date: 01 May 2000
Pages759–766OBJECTIVE: Data from a full assessment of auditory perception in patients with schizophrenia were used to investigate whether auditory hallucinations are associated with abnormality of central auditory processing. METHOD: Three groups of subjects ...
https://doi.org/10.1176/appi.ajp.157.5.759Publication date: 01 May 2000
Pages767–771OBJECTIVE: Patients with schizophrenia have deficits in attention, cognition, and information processing. Measures such as P50 suppression are used to study cognitive and attentional dysfunction among these patients. P50 suppression is an operational ...
https://doi.org/10.1176/appi.ajp.157.5.767Publication date: 01 May 2000
Pages772–780OBJECTIVE: Abnormalities of attention are considered the fundamental deficits in cognitive function manifested by patients with schizophrenia. The authors administered variations of two types of cognitive tasks to patients with schizophrenia (N=20) and ...
https://doi.org/10.1176/appi.ajp.157.5.772Publication date: 01 May 2000
Pages781–788OBJECTIVE: Patients affected by schizophrenia show deficits in both visual perception and working memory. The authors tested early-stage vision and working memory in subjects with schizotypal personality disorder, which has been biologically associated ...
https://doi.org/10.1176/appi.ajp.157.5.781Publication date: 01 May 2000
Pages787–793OBJECTIVE: The authors contrasted verbal and nonverbal measures of attention and memory in patients with DSM-IV-defined schizotypal personality disorder in order to expand on their previous findings of verbal learning deficits in these patients and to ...
https://doi.org/10.1176/appi.ajp.157.5.787Publication date: 01 May 2000
Pages794–800OBJECTIVE: As both premorbid neurodevelopmental impairments and familial risk factors for schizophrenia are prominent in childhood-onset cases (with onset of psychosis by age 12), their relationship was examined. METHOD: Premorbid language, motor, and ...
https://doi.org/10.1176/appi.ajp.157.5.794Publication date: 01 May 2000
Pages801–807OBJECTIVE: Although case-control investigations have shown an association between obstetric complications and schizophrenia, particularly among patients with early onsets, cohort studies have mostly failed to confirm this effect. The authors examined ...
https://doi.org/10.1176/appi.ajp.157.5.801Publication date: 01 May 2000
Pages808–815OBJECTIVE: Previous studies have suggested that there may be an association between longer duration of untreated psychosis and poor outcome in schizophrenia. These studies have been interpreted as providing evidence that untreated psychosis may constitute ...
https://doi.org/10.1176/appi.ajp.157.5.808Brief Report
Publication date: 01 May 2000
Pages816–818OBJECTIVE: Symptom decline in attention deficit hyperactivity disorder (ADHD) was examined with different definitions of remission.METHOD: Symptoms in 128 boys were measured five times over 4 years. The prevalences of syndromatic (less than full syndrome),...
https://doi.org/10.1176/appi.ajp.157.5.816Publication date: 01 May 2000
Pages818–820OBJECTIVE: The authors sought to replicate open-label findings showing that specific criteria for explosive temper and mood lability identify disruptive youth who improve while receiving the anticonvulsant divalproex sodium.METHOD: Twenty outpatient ...
https://doi.org/10.1176/appi.ajp.157.5.818Publication date: 01 May 2000
Pages821–823OBJECTIVE: The authors sought to determine whether the administration of flumazenil would induce marked panic symptoms in women suffering from premenstrual dysphoric disorder.METHOD: Ten women with premenstrual dysphoric disorder and 11 comparison ...
https://doi.org/10.1176/appi.ajp.157.5.821Publication date: 01 May 2000
Pages823–825OBJECTIVE: The authors investigated whether absence of the adhesio interthalamica in patients with schizophrenia constitutes a marker of early developmental neuropathological changes.METHOD: Thirty male patients with schizophrenia and 30 healthy male ...
https://doi.org/10.1176/appi.ajp.157.5.823Publication date: 01 May 2000
Pages826–828OBJECTIVE: The purpose of this study was to evaluate the effects of high-dose oral glycine on positive and negative symptoms and cognitive function when added to clozapine in adults with schizophrenia.METHOD: The authors conducted a double-blind, placebo-...
https://doi.org/10.1176/appi.ajp.157.5.826Publication date: 01 May 2000
Pages828–830OBJECTIVE: The authors’ goal in this study was to compare the size of olfactory bulbs of patients with schizophrenia and those of healthy subjects.METHOD: Magnetic resonance imaging scans of olfactory bulbs were obtained from 26 patients with ...
https://doi.org/10.1176/appi.ajp.157.5.828Publication date: 01 May 2000
Pages831–833OBJECTIVE: Glycogen synthase kinase-3 (GSK-3) is a protein kinase that is highly abundant in the brain. It is involved in signal transduction cascades of multiple cellular processes, particularly neurodevelopment. In an attempt to explore possible ...
https://doi.org/10.1176/appi.ajp.157.5.831Letter to the Editor
Book Forum: Mind and Brain
Book Forum: Genetics
Book Forum: Ethnicity and Culture
Book Forum: Ethnicity And Culture
Book Forum: Psychotherapy
Book Forum: Forensic Issues
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