American Journal of Psychiatry
- Volume 157
- Number 6
- June 2000
Editorial
Reviews and Overviews
Publication date: 01 June 2000
Pages854–866OBJECTIVE: Obesity is a highly prevalent condition with significant health implications. This report summarizes recent clinically relevant findings concerning the pathogenesis and treatment of obesity and considers their implications for psychiatric ...
https://doi.org/10.1176/appi.ajp.157.6.854Publication date: 01 June 2000
Pages867–876OBJECTIVE: Neuropsychiatric symptoms are commonly associated with chronic hepatitis C virus infection, its sequelae, and its treatment. In particular, interferon, a primary component of treatment for chronic hepatitis C, has been strongly associated with ...
https://doi.org/10.1176/appi.ajp.157.6.867Images In Neuroscience
Clinical Case Conference
Images In Psychiatry
Article
Publication date: 01 June 2000
Pages886–895OBJECTIVE: The nosology for eating disorders, despite having been extensively revised over time, may not capture the natural clustering of eating-related pathology as it occurs in general population samples.METHOD: Detailed information about anorectic and ...
https://doi.org/10.1176/appi.ajp.157.6.886Publication date: 01 June 2000
Pages896–903OBJECTIVE: Stressful life events are known to precipitate major depression. However, it remains unclear why some individuals who experience adverse events develop depression whereas others do not, and how the occurrence of life events affects treatment ...
https://doi.org/10.1176/appi.ajp.157.6.896Publication date: 01 June 2000
Pages904–910OBJECTIVE: Opinions differ about the effects of the Holocaust on the adult offspring of survivors. The authors studied cancer patients who were second-generation Holocaust survivors in an attempt to determine whether they react to their illness with the ...
https://doi.org/10.1176/appi.ajp.157.6.904Publication date: 01 June 2000
Pages911–916OBJECTIVE: The authors sought to assess the severity and longitudinal course of posttraumatic stress, anxiety, and depressive reactions among two groups of adults differentially exposed to severe and mild earthquake trauma and a third group exposed to ...
https://doi.org/10.1176/appi.ajp.157.6.911Minor Physical Anomalies and Family Adversity as Risk Factors for Violent Delinquency in Adolescence
Publication date: 01 June 2000
Pages917–923OBJECTIVE: Minor physical anomalies are considered indicators of disruption in fetal development. They have been found to predict behavioral problems and psychiatric disorders. This study examined the extent to which minor physical anomalies, family ...
https://doi.org/10.1176/appi.ajp.157.6.917Publication date: 01 June 2000
Pages924–930OBJECTIVE: Endocrine factors are purported to play a role in the etiology of postpartum depression, but direct evidence for this role is lacking. The authors investigated the possible role of changes in gonadal steroid levels in postpartum depression by ...
https://doi.org/10.1176/appi.ajp.157.6.924Publication date: 01 June 2000
Pages931–939OBJECTIVE: There have been few naturalistic follow-up studies of dysthymic disorder. This study describes the 5-year course and outcome of dysthymic disorder.METHOD: The authors conducted a prospective, longitudinal follow-up study of 86 outpatients with ...
https://doi.org/10.1176/appi.ajp.157.6.931Publication date: 01 June 2000
Pages940–947OBJECTIVE: Chronic depression starts at an early age for many individuals and could affect their accumulation of “human capital” (i.e., education, higher amounts of which can broaden occupational choice and increase earnings potential). The authors ...
https://doi.org/10.1176/appi.ajp.157.6.940Publication date: 01 June 2000
Pages948–955OBJECTIVE: Although genetic factors have been implicated in the etiology of bipolar disorder, no specific gene has been conclusively identified. Given the link between abnormalities in serotonergic neurotransmission and bipolar disorder, a candidate gene ...
https://doi.org/10.1176/appi.ajp.157.6.948Publication date: 01 June 2000
Pages956–962OBJECTIVE: Given the adverse impact of anxiety on treatment outcome in unipolar depression and the paucity of data on the role of anxiety in bipolar disorder, the authors sought to determine the effect of anxiety on the acute treatment response of ...
https://doi.org/10.1176/appi.ajp.157.6.956Publication date: 01 June 2000
Pages963–967OBJECTIVE: The maximum output charge for ECT devices is limited to 576 millicoulombs in the United States, although there are no data ensuring that this limit will allow consistently effective treatments. The authors examined whether this limit has a ...
https://doi.org/10.1176/appi.ajp.157.6.963Publication date: 01 June 2000
Pages968–974OBJECTIVE: This study evaluated the efficacy and safety of fixed doses of once-daily extended-release (XR) venlafaxine in outpatients with generalized anxiety disorder without concomitant major depressive disorder.METHOD: Adult outpatients with ...
https://doi.org/10.1176/appi.ajp.157.6.968Publication date: 01 June 2000
Pages975–981OBJECTIVE: The goal of this 5-year naturalistic study of patients treated with clozapine was to examine the incidence of treatment-emergent diabetes mellitus in relation to other factors, including weight gain, lipid abnormalities, age, clozapine dose, ...
https://doi.org/10.1176/appi.ajp.157.6.975Publication date: 01 June 2000
Pages982–986OBJECTIVE: The efficacy of clozapine was examined in a group of patients with treatment-refractory bipolar disorder, manic type with psychotic features.METHOD: Twenty-two subjects with treatment-refractory bipolar disorder with active manic and psychotic ...
https://doi.org/10.1176/appi.ajp.157.6.982Publication date: 01 June 2000
Pages987–993OBJECTIVE: Atypical antipsychotic medications have generally been found to be more effective than conventional antipsychotics in the treatment of negative symptoms. Whether the benefits derived from the atypical agents are the result of improvements in ...
https://doi.org/10.1176/appi.ajp.157.6.987Publication date: 01 June 2000
Pages994–1003OBJECTIVE: Although a family history of schizophrenia has been associated with negative symptoms, family history is inconsistently related to the presence of the deficit syndrome.METHOD: The authors assessed family history and the deficit syndrome in 99 ...
https://doi.org/10.1176/appi.ajp.157.6.994Brief Report
Publication date: 01 June 2000
Pages1004–1006OBJECTIVE: The authors’ goal was to assess the efficacy of sertraline in the treatment of binge eating disorder.METHOD: Thirty-four outpatients with DSM-IV binge eating disorder were randomly assigned to receive either sertraline (N=18) or placebo (N=16) ...
https://doi.org/10.1176/appi.ajp.157.6.1004Publication date: 01 June 2000
Pages1006–1008OBJECTIVE: The authors’ goal was to determine whether sertraline attenuates the increased platelet activation seen among depressed patients.METHOD: They tested 21 otherwise healthy patients with untreated major depressive episode who were 25–52 years old ...
https://doi.org/10.1176/appi.ajp.157.6.1006Publication date: 01 June 2000
Pages1009–1011OBJECTIVE: This study examines the influence of cognitive impairment, premorbid intelligence, and decision-making capacity to complete advance directives on the treatment preferences for life-sustaining medical therapy in the elderly.METHOD: One hundred ...
https://doi.org/10.1176/appi.ajp.157.6.1009Publication date: 01 June 2000
Pages1012–1013OBJECTIVE: The goal of this study was to determine the frequency of dissociative disorders in Dutch psychiatric inpatients.METHOD: During a period of 12 months, 122 consecutively admitted adult psychiatric patients were screened with the Dissociative ...
https://doi.org/10.1176/appi.ajp.157.6.1012Publication date: 01 June 2000
Pages1014–1016OBJECTIVE: The authors used seven definitions of response in panic disorder to compare patient-rated improvements in quality of life between patients with panic disorder who responded to sertraline and those who responded to placebo.METHOD: They combined ...
https://doi.org/10.1176/appi.ajp.157.6.1014Publication date: 01 June 2000
Pages1016–1018OBJECTIVE: The authors compared serotonin receptor binding in patients with schizophrenia and healthy comparison subjects.METHOD: They used positron emission tomography with [18F]setoperone to examine six patients with schizophrenia who had never been ...
https://doi.org/10.1176/appi.ajp.157.6.1016Publication date: 01 June 2000
Pages1019–1020OBJECTIVE: The authors’ goal was to study the relationship between subjective experience during treatment with olanzapine or risperidone and dopamine D2 receptor occupancy in stabilized patients with schizophrenia.METHOD: Subjective experience, ...
https://doi.org/10.1176/appi.ajp.157.6.1019Letter to the Editor
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