American Journal of Psychiatry
- Volume 173
- Number 4
- April 2016
Editorials
Introspection
Treatment in Psychiatry
Perspectives in Global Mental Health
Images in Neuroscience
Reviews and Overviews
Publication date: 10 November 2015
Pages334–343The cumulative strain of 14 years of war on service members, veterans, and their families, together with continuing global threats and the unique stresses of military service, are likely to be felt for years to come. Scientific as well as political ...
https://doi.org/10.1176/appi.ajp.2015.15040553Publication date: 15 January 2016
Pages344–361Impaired emotion regulation contributes to the development and severity of substance use disorders (substance disorders). This review summarizes the literature on alterations in emotion regulation neural circuitry in substance disorders, particularly in ...
https://doi.org/10.1176/appi.ajp.2015.15060710Articles
Publication date: 20 October 2015
Pages362–372Objective: The primary aim of this study was to compare the impact of NAVIGATE, a comprehensive, multidisciplinary, team-based treatment approach for first-episode psychosis designed for implementation in the U.S. health care system, with community care on ...
https://doi.org/10.1176/appi.ajp.2015.15050632Publication date: 07 December 2015
Pages373–384Objective: Clinical phenomenology remains the primary means for classifying psychoses despite considerable evidence that this method incompletely captures biologically meaningful differentiations. Rather than relying on clinical diagnoses as the gold ...
https://doi.org/10.1176/appi.ajp.2015.14091200Publication date: 06 October 2015
Pages385–391Objective: The Consortium on the Genetics of Schizophrenia Family Study evaluated 12 primary and other supplementary neurocognitive and neurophysiological endophenotypes in schizophrenia probands and their families. Previous analyses of prepulse inhibition ...
https://doi.org/10.1176/appi.ajp.2015.15050605Publication date: 18 December 2015
Pages392–399Objective: Animal models suggest that the development of psychosis involves hyperactivity in the hippocampus that drives increased activity in the midbrain and basal ganglia. The authors examined this hypothesis by measuring resting perfusion in the ...
https://doi.org/10.1176/appi.ajp.2015.15040485Publication date: 10 November 2015
Pages400–407Objective: Accumulating evidence indicates that manic symptoms below the threshold for hypomania (mixed features) are common in individuals with major depressive disorder. This form of depression is often severe and is associated with an increased risk for ...
https://doi.org/10.1176/appi.ajp.2015.15060770Publication date: 19 February 2016
Pages408–417Objective: ECT is the most effective treatment for severe depression. Previous efficacy studies, using thrice-weekly brief-pulse ECT, reported that high-dose (6× seizure threshold) right unilateral ECT is similar to bitemporal ECT but may have fewer ...
https://doi.org/10.1176/appi.ajp.2015.15030372Publication date: 22 January 2016
Pages418–428Objective: Appetite and weight changes are common but variable diagnostic markers in major depressive disorder: some depressed individuals manifest increased appetite, while others lose their appetite. Many of the brain regions implicated in appetitive ...
https://doi.org/10.1176/appi.ajp.2015.15020162