American Journal of Psychiatry
- Volume 155
- Number 3
- March 1998
Editorial
Images In Neuroscience
Special Article
Publication date: 01 March 1998
Pages325–336OBJECTIVE: Current knowledge of the relationship between epilepsy and schizophrenia-like psychosis is examined, and the proposed pathogenetic mechanisms are evaluated. METHOD: The author provides an overview of the published literature on epilepsy and ...
https://doi.org/10.1176/ajp.155.3.325Regular Article
Publication date: 01 March 1998
Pages337–343OBJECTIVE: The CNS metabolic response to a neuroleptic challenge in treatment-responsive and nonresponsive schizophrenic patients was measured in order to examine the relation between treatment outcome and the capacity to alter neurochemical function in ...
https://doi.org/10.1176/ajp.155.3.337Publication date: 01 March 1998
Pages344–349OBJECTIVE: Although it is documented that brain dopamine activity declines with age, the functional significance of this is not known. This study assessed the relation between measures of brain dopamine activity and indexes of motor and cognitive function ...
https://doi.org/10.1176/ajp.155.3.344Publication date: 01 March 1998
Pages350–354OBJECTIVE: Three hypotheses were tested: 1) schizophrenic patients would report more impairments on a self-rating scale for negative symptoms than normal subjects and attribute higher levels of distress to these impairments, 2) schizophrenic patients ...
https://doi.org/10.1176/ajp.155.3.350Publication date: 01 March 1998
Pages355–364OBJECTIVE: The 1966 North Finland general population birth cohort was studied to determine whether abnormalities during pregnancy, delivery, and the neonatal period are associated with adult-onset schizophrenia. METHOD: The authors included all 11,017 ...
https://doi.org/10.1176/ajp.155.3.355Publication date: 01 March 1998
Pages365–366OBJECTIVE: The authors' goal was to study the recommended dose schedule for risperidone. METHOD: They obtained computerized pharmacy data on 1,283 inpatients with the diagnoses of schizophrenia or schizoaffective disorder who were treated with ...
https://doi.org/10.1176/ajp.155.3.365Publication date: 01 March 1998
Pages367–372OBJECTIVE: This study examined whether a selective serotonin reuptake inhibitor (paroxetine) had comparable efficacy but greater tolerability than a tricyclic antidepressant (imipramine) in depressed patients with HIV infection. METHOD: Seventy-five HIV-...
https://doi.org/10.1176/ajp.155.3.367Publication date: 01 March 1998
Pages373–379OBJECTIVE: The authors sought to test the causal hypothesis that serotonergic function modulates aspects of the normal spectrum of individual differences in affective experience and social behavior in humans. METHOD: A selective serotonin reuptake ...
https://doi.org/10.1176/ajp.155.3.373Publication date: 01 March 1998
Pages380–384OBJECTIVE: This study used fluorine-19 magnetic resonance spectroscopy (19F MRS) to characterize the elimination of fluvoxamine from the human brain after abrupt drug discontinuation. The elimination half-lives of fluvoxamine in brain and plasma were ...
https://doi.org/10.1176/ajp.155.3.380Publication date: 01 March 1998
Pages385–389OBJECTIVE: With the goal of ultimately finding early suicide predictors, the authors undertook a study of aborted suicide attempts. They defined such an attempt as an event in which an individual comes close to attempting suicide but does not complete the ...
https://doi.org/10.1176/ajp.155.3.385Publication date: 01 March 1998
Pages390–396OBJECTIVE: The objective of this study was to determine the annual incidence of homicide-suicide and to compare patterns and antecedents in old and young spousal/consortial cases. METHOD: Homicide-suicide cases were ascertained in four medical examiner ...
https://doi.org/10.1176/ajp.155.3.390Publication date: 01 March 1998
Pages397–404OBJECTIVE: The authors' goal was to characterize psychiatric practice by reporting findings from the 1996 National Survey of Psychiatric Practice. METHOD: A random sample of 1,481 APA members was selected to participate in the study; 1,375 APA members ...
https://doi.org/10.1176/ajp.155.3.397Publication date: 01 March 1998
Pages405–408OBJECTIVE: This study attempts to determine the ratio of full-time-equivalent psychiatrists to members and that of nonphysician mental health professionals to psychiatrists in staff and group model health maintenance organizations (HMOs), and to compare ...
https://doi.org/10.1176/ajp.155.3.405Publication date: 01 March 1998
Pages409–414OBJECTIVE: This paper outlines a number of misapplications of boundary theory in both regulatory settings and clinical situations. METHOD: The authors review clinical vignettes that illustrate the difference between boundary crossings, which lead to ...
https://doi.org/10.1176/ajp.155.3.409Clinical Case Conference
Images in Psychiatry
Brief Report
Publication date: 01 March 1998
Pages422–424OBJECTIVE: Genomic DNA of monozygotic twins discordant for schizophrenia was analyzed to determine whether their genomes were truly identical. METHOD: The subjects were monozygotic male twins, one of whom had DSM-III-R schizophrenia, undifferentiated ...
https://doi.org/10.1176/ajp.155.3.422Publication date: 01 March 1998
Pages425–427OBJECTIVE: The purpose of this study was to determine if P300 latency is prolonged in geri~atric depression and if longer P300 latency and deficits in initiation and errors of perseveration in depressed elderly patients are related to risk factors for ...
https://doi.org/10.1176/ajp.155.3.425Publication date: 01 March 1998
Pages428–430OBJECTIVE: There is a substantial relationship between dysfunctional cognitions and the clinical course of major depression. This study examined whether this association extends to patients with seasonal affective disorder. METHOD: A revised version of ...
https://doi.org/10.1176/ajp.155.3.428Publication date: 01 March 1998
Pages431–433OBJECTIVE: The purpose of this pilot study was to describe the initial course of psychiatric illness in the adolescent children of parents with bipolar disorder who were divided into two groups on the basis of their response to long-term lithium ...
https://doi.org/10.1176/ajp.155.3.431Publication date: 01 March 1998
Pages434–436OBJECTIVE: The authors evaluated the effect of sex on data derived from activation studies using blood-oxygenation-level-dependent (BOLD) functional magnetic resonance imaging (MRI). METHOD: Gradient echo-echo planar imaging was used to measure BOLD ...
https://doi.org/10.1176/ajp.155.3.434Publication date: 01 March 1998
Pages437–438OBJECTIVE: This study sought to determine whether personality traits of depressed pa~tients could be assessed similarly by informants and self-reports of the patients themselves. METHOD: Forty-six depressed outpatients completed the self-report (first-...
https://doi.org/10.1176/ajp.155.3.437