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American Journal of Psychiatry

  • Volume 155
  • Number 4
  • April 1998

Editorial

Images in Psychiatry

Special Article

Publication date: 01 April 1998

Pages457–469

In an attempt to place psychiatric thinking and the training of future psychiatrists more centrally into the context of modern biology, the author outlines the beginnings of a new intellectual framework for psychiatry that derives from current biological ...

https://doi.org/10.1176/ajp.155.4.457

Regular Article

Publication date: 01 April 1998

Pages470–473

OBJECTIVE: Humans experience the subjective effects of mu and kappa opioid agonists differently: mu agonists produce mainly euphoria, while kappa agonists are more likely to produce dysphoria. This study tested the hypothesis that these subjective effects ...

https://doi.org/10.1176/ajp.155.4.470

Publication date: 01 April 1998

Pages474–478

OBJECTIVE: Determinants of individual vulnerability to alcohol withdrawal symptoms are largely unknown. Because of the substantial role of monoaminergic transporters in limiting time and space effects of synaptic neurotransmission, the dopamine ...

https://doi.org/10.1176/ajp.155.4.474

Publication date: 01 April 1998

Pages479–485

OBJECTIVE: This study investigated the progression from conduct disorder to antisocial personality disorder among individuals treated for adolescent substance abuse. This issue is important because of the poor outcomes observed among individuals with ...

https://doi.org/10.1176/ajp.155.4.479

Publication date: 01 April 1998

Pages486–492

OBJECTIVE: The DSM-IV criteria for substance use disorders were incorporated into the 1995 Minnesota Student Survey in order to estimate the need for alcohol/drug treatment among adolescents in the state. This study used data from the survey to examine ...

https://doi.org/10.1176/ajp.155.4.486

Publication date: 01 April 1998

Pages493–498

OBJECTIVE: Numerous studies have examined the adolescent and young adult fate of children with attention deficit hyperactivity disorder (ADHD). In marked contrast, relatively little is known about the adult outcome of these children. There have been only ...

https://doi.org/10.1176/ajp.155.4.493

Publication date: 01 April 1998

Pages499–504

OBJECTIVE: The purpose of this study was to compare the short-term efficacy and safety of risperidone and clozapine in treatment-resistant chronic schizophrenic patients. METHOD: In a controlled double-blind, multicenter study, 86 inpatients with chronic ...

https://doi.org/10.1176/ajp.155.4.499

Publication date: 01 April 1998

Pages505–508

OBJECTIVE: This study examined the binding to cortical serotonin 5-HT2A receptors of conventional doses of the typical neuroleptic chlorpromazine in comparison with clozapine, the prototype atypical antipsychotic, and amisulpride, a specific dopamine D2-D...

https://doi.org/10.1176/ajp.155.4.505

Publication date: 01 April 1998

Pages516–522

OBJECTIVE: Severe and persistent mental illnesses are often lifelong and characterized by intermittent exacerbations requiring hospitalization. Providing needed care within budgetary constraints to this largely publicly subsidized population requires ...

https://doi.org/10.1176/ajp.155.4.516

Publication date: 01 April 1998

Pages523–529

OBJECTIVE: In 1989, Philadelphia began a bold experiment involving the total shutdown of a 500-bed state hospital. This study examines the service utilization and cost of treating individuals with serious mental illness in a community-based care system in ...

https://doi.org/10.1176/ajp.155.4.523

Publication date: 01 April 1998

Pages530–535

OBJECTIVE: The aim of this research was to study the relationship between the clinical interview skills of primary care physicians and their psychodiagnostic ability during office visits. METHOD: Ten doctors took part in the study, and 233 patients were ...

https://doi.org/10.1176/ajp.155.4.530

Publication date: 01 April 1998

Pages536–542

OBJECTIVE: The effects of religious belief and activity on remission of depression were examined in medically ill hospitalized older patients. METHOD: Consecutive patients aged 60 years or over who had been admitted to medical inpatient services at a ...

https://doi.org/10.1176/ajp.155.4.536

Publication date: 01 April 1998

Pages543–547

OBJECTIVE: Suicidal behavior has been associated with reduced central serotonergic function. Because selective serotonin reuptake inhibitors (SSRIs) enhance serotonergic function, the authors studied the efficacy of an SSRI, paroxetine, in the prevention ...

https://doi.org/10.1176/ajp.155.4.543

Publication date: 01 April 1998

Pages548–551

OBJECTIVE: While pharmacological interventions are of established utility in bulimia nervosa, medications have no clear role in the treatment of anorexia nervosa. Because patients with anorexia nervosa frequently exhibit mood disturbances and symptoms of ...

https://doi.org/10.1176/ajp.155.4.548

Brief Report

Publication date: 01 April 1998

Pages552–554

OBJECTIVE: The authors' goal was to use structured clinical interviews to characterize the type and frequency of mental illness in adults with fetal alcohol syndrome or fetal alcohol effects. METHOD: Twenty-five subjects who met criteria for fetal alcohol ...

https://doi.org/10.1176/ajp.155.4.552

Publication date: 01 April 1998

Pages555–557

OBJECTIVE: The prevalences of obsessive-compulsive symptoms in patients suffering from blepharospasm and in those with hemifacial spasm were determined. The two conditions have similar symptoms, but only blepharospasm is etiologically linked to basal ...

https://doi.org/10.1176/ajp.155.4.555

Publication date: 01 April 1998

Pages558–559

OBJECTIVE: Changes in defense mechanisms after treatment of patients with obsessive-compulsive disorder (OCD) were measured by using an established rating scale. METHOD: Before and after 7-week group behavior therapy, 17 patients with DSM-III-R OCD were ...

https://doi.org/10.1176/ajp.155.4.558

Publication date: 01 April 1998

Pages560–561

OBJECTIVE: The authors' goal was to assess naturalistic treatment outcome in trichotillomania. METHOD: Sixty-three patients who had been treated in a specialty clinic for trichotillomania over a period of 6 years were contacted. The patients were given ...

https://doi.org/10.1176/ajp.155.4.560

Publication date: 01 April 1998

Pages562–564

OBJECTIVE: The authors' goal was to describe the characteristics of posttraumatic stress disorder (PTSD) symptoms on resettlement in the United States and at 1-year follow-up among Bosnian refugees as well as possible factors affecting the PTSD symptom ...

https://doi.org/10.1176/ajp.155.4.562

Publication date: 01 April 1998

Pages565–567

OBJECTIVE: The authors examined the association between three lifetime medication variables (cumulative amount of neuroleptics, number of interruptions in neuroleptic treatment, cumulative amount of anticholinergics) and the occurrence and severity of ...

https://doi.org/10.1176/ajp.155.4.565

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Letter to the Editor

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