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American Journal of Psychiatry

  • Volume 155
  • Number 5
  • May 1998

Editorial

Images in Neuroscience

Special Article

Publication date: 01 May 1998

Pages582–589

At a time of strong biological emphasis in psychiatry, it is important to emphasize that relationships with important others may play a crucial role in individual outcome. Psychoanalytic theories in the form of object relations, self psychology, and ...

https://doi.org/10.1176/ajp.155.5.582

Regular Article

Publication date: 01 May 1998

Pages590–595

OBJECTIVE: Anticipation (i.e., the decrease in age at onset or the increase in severity of a disorder in successive generations) has recently been reappraised as a key to understanding the genetics of some familial illnesses. The purpose of this study was ...

https://doi.org/10.1176/ajp.155.5.590

Publication date: 01 May 1998

Pages596–602

OBJECTIVE: Panic disorder with or without agoraphobia has a chronic relapsing course. Factors associated with poor outcome include early onset of illness and phobic avoidance. Several, but not all, authors have found a worse clinical course for women. ...

https://doi.org/10.1176/ajp.155.5.596

Publication date: 01 May 1998

Pages603–609

OBJECTIVE: The purpose of this study was to compare the therapeutic effect of exercise for patients with panic disorder to a drug treatment of proven efficacy and to placebo. METHOD: Forty-six outpatients suffering from moderate to severe panic disorder ...

https://doi.org/10.1176/ajp.155.5.603

Publication date: 01 May 1998

Pages610–612

OBJECTIVE: Flumazenil is a benzodiazepine receptor antagonist that has been reported to provoke panic attacks in patients with panic disorder. This study was undertaken to compare the effects of flumazenil and sodium lactate, the most widely studied panic ...

https://doi.org/10.1176/ajp.155.5.610

Publication date: 01 May 1998

Pages613–619

OBJECTIVE: This article presents epidemiologic data on the distinction between social phobia characterized by pure speaking fears and that characterized by other social fears. METHOD: The data come from the National Comorbidity Survey (N=8,098). Social ...

https://doi.org/10.1176/ajp.155.5.613

Publication date: 01 May 1998

Pages620–624

OBJECTIVE: Using the DSM-IV diagnostic criteria for acute stress disorder, the authors examined whether the acute psychological effects of being a bystander to violence involving mass shootings in an office building predicted later posttraumatic stress ...

https://doi.org/10.1176/ajp.155.5.620

Publication date: 01 May 1998

Pages625–629

OBJECTIVE: The aim of this study was to index the frequency of occurrence of acute stress disorder following mild traumatic brain injury and to determine its utility in predicting posttraumatic stress disorder (PTSD). METHOD: Consecutive adult patients ...

https://doi.org/10.1176/ajp.155.5.625

Publication date: 01 May 1998

Pages630–637

OBJECTIVE: The purpose of this study was to prospectively evaluate the onset, overlap, and course of posttraumatic stress disorder (PTSD) and major depression following traumatic events. METHOD: The occurrence of PTSD and major depression and the ...

https://doi.org/10.1176/ajp.155.5.630

Publication date: 01 May 1998

Pages638–645

OBJECTIVE: Effects of long-term lithium treatment for depressive and manic phases of type I and type II bipolar disorders were compared. METHOD: Clinical research records of 317 patients with DSM-IV-defined bipolar disorder (188 with type I and 129 with ...

https://doi.org/10.1176/ajp.155.5.638

Publication date: 01 May 1998

Pages646–652

OBJECTIVE: The authors studied the 12-month course of illness following hospitalization for a manic or mixed episode of bipolar disorder to identify potential outcome predictors. METHOD: They recruited 134 patients with DSM-III-R bipolar disorder who were ...

https://doi.org/10.1176/ajp.155.5.646

Publication date: 01 May 1998

Pages653–659

OBJECTIVE: This study examined the 30-month stability of axis II conditions. METHOD: One hundred eight depressed outpatients received comprehensive, semistructured personality disorder assessments at baseline and at follow-up. RESULTS: The diagnostic ...

https://doi.org/10.1176/ajp.155.5.653

Publication date: 01 May 1998

Pages660–665

OBJECTIVE: The purpose of this study was to determine the cardiovascular effects of fluoxetine in depressed patients with cardiac disease. METHOD: Twenty-seven depressed patients (26% of whom were female and whose average age was 73 years) who had ...

https://doi.org/10.1176/ajp.155.5.660

Publication date: 01 May 1998

Pages666–671

OBJECTIVE: Heterotrimeric G proteins were previously implicated in the biochemical mechanisms underlying the pathophysiology and treatment of mood disorders. Low function and immunoreactivity of G proteins were observed in patients with major depression. ...

https://doi.org/10.1176/ajp.155.5.666

Publication date: 01 May 1998

Pages672–677

OBJECTIVE: The goal of this study was to examine cognitive antecedents of psychosis by determining whether variability in IQ during childhood was predictive of psychotic symptoms in adulthood. METHOD: Deviant responder analyses were used to examine ...

https://doi.org/10.1176/ajp.155.5.672

Publication date: 01 May 1998

Pages678–685

OBJECTIVE: A previous cross-sectional study of brain morphology in childhood-onset schizophrenia indicated sparing of the temporal lobes from processes reducing total cerebral volume in this population. In the present study, subjects with childhood-onset ...

https://doi.org/10.1176/ajp.155.5.678

Clinical Case Conference

Images in Psychiatry

Brief Report

Publication date: 01 May 1998

Pages690–692

OBJECTIVE: The authors' goal was to study the serum sertraline levels of breast-feeding mothers and their infants. METHOD: They obtained serum levels of sertraline and N-desmethylsertraline in nine mother-infant pairs. RESULTS: Sertraline levels were very ...

https://doi.org/10.1176/ajp.155.5.690

Publication date: 01 May 1998

Pages693–695

OBJECTIVE: The authors assessed the experimental noradrenergic compound tomoxetine as an alternative treatment for adult attention deficit hyperactivity disorder (ADHD). METHOD: They conducted a double-blind, placebo-controlled, crossover study of ...

https://doi.org/10.1176/ajp.155.5.693

Publication date: 01 May 1998

Pages696–698

OBJECTIVE: The authors' goal was to explore the nature of attention deficit hyperactivity disorder (ADHD) in African American children, which has received scant attention by psychiatric researchers. METHOD: Subjects were 19 African American children with ...

https://doi.org/10.1176/ajp.155.5.696

Publication date: 01 May 1998

Pages698–700

OBJECTIVE: The authors investigated the relationships between concentrations of two acute-phase proteins, α1-antichymotrypsin (ACT) and α2-macroglobulin (MAC), and cognitive impairment in the very old. METHOD: Concentrations of ACT and MAC were determined ...

https://doi.org/10.1176/ajp.155.5.698

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