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American Journal of Psychiatry

  • Volume 156
  • Number 8
  • August 1999

Editorial

Images In Neuroscience

Special

Publication date: 01 August 1999

Pages1138–1148

OBJECTIVE: Patients with concurrent schizophrenic and mood symptoms are often treated with antipsychotics plus antidepressant or thymoleptic drugs. The authors review the literature on treatment of two overlapping groups of patients: those with ...

https://doi.org/10.1176/ajp.156.8.1138

Regular Article

Publication date: 01 August 1999

Pages1149–1158

OBJECTIVE: Sleep deprivation has been shown to have an antidepressant benefit in a subgroup of depressed patients. Functional imaging studies by the authors and others have suggested that patients with elevated metabolic rates in the anterior cingulate ...

https://doi.org/10.1176/ajp.156.8.1149

Publication date: 01 August 1999

Pages1159–1163

OBJECTIVE: Anomalous cerebral asymmetry in schizophreniform disorders has been described, but its presence in psychotic mood disorders has not been established. Measures of cerebral asymmetry may distinguish patients with psychotic mood disorders from ...

https://doi.org/10.1176/ajp.156.8.1159

Publication date: 01 August 1999

Pages1164–1169

OBJECTIVE: Case series and follow-up studies suggest that clozapine may have mood-stabilizing properties in addition to antipsychotic action in patients with schizoaffective disorder, bipolar type, and bipolar I disorder, but the generalizability of these ...

https://doi.org/10.1176/ajp.156.8.1164

Publication date: 01 August 1999

Pages1170–1176

OBJECTIVE: Fluoxetine has been associated with weight loss during acute treatment, but no controlled studies of weight change during long-term treatment with fluoxetine or other selective serotonin reuptake inhibitors have been reported. Weights were ...

https://doi.org/10.1176/ajp.156.8.1170

Publication date: 01 August 1999

Pages1177–1181

OBJECTIVE: This study compared the long-term efficacy of two fixed plasma levels of nortriptyline in preventing or delaying recurrence of major depression in elderly patients and in minimizing residual depressive symptoms and somatic complaints. METHOD: ...

https://doi.org/10.1176/ajp.156.8.1177

Publication date: 01 August 1999

Pages1182–1189

OBJECTIVE: The purpose of this study was to determine the prognosis of depression in elderly community and primary care populations. METHOD: Medline and PsycINFO were searched for potentially relevant articles published from January 1981 to November 1996 ...

https://doi.org/10.1176/ajp.156.8.1182

Publication date: 01 August 1999

Pages1190–1199

OBJECTIVE: In an exploration of the schizophrenia spectrum, the authors compared thalamic size, shape, and metabolic activity in unmedicated patients with schizophrenia and schizotypal personality disorder to findings in age- and sex-matched healthy ...

https://doi.org/10.1176/ajp.156.8.1190

Publication date: 01 August 1999

Pages1200–1204

OBJECTIVE: For many years, it has been assumed that medications affect brain chemistry and physiology but not structure. Recent reports suggest that neuroleptic medication changes basal ganglia volume. To explore this possibility, the authors assessed for ...

https://doi.org/10.1176/ajp.156.8.1200

Publication date: 01 August 1999

Pages1205–1208

OBJECTIVE: The authors examined phospholipids and high-energy phosphorus metabolism in the temporal lobes of drug-naive schizophrenic patients. METHOD: In vivo 31P magnetic resonance spectroscopy was performed on 17 first-episode, drug-naive schizophrenic ...

https://doi.org/10.1176/ajp.156.8.1205

Publication date: 01 August 1999

Pages1209–1215

OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a highly prevalent childhood psychiatric disorder characterized by impaired attention, excessive motor activity, and impulsivity. Despite extensive investigation of the neuropathophysiology of ...

https://doi.org/10.1176/ajp.156.8.1209

Publication date: 01 August 1999

Pages1216–1222

OBJECTIVE: Impaired neuropsychological performance involving abstraction-flexibility, memory, motor function, and attention has frequently been reported in schizophrenia as well as in attention deficit hyperactivity disorder (ADHD). This study represents ...

https://doi.org/10.1176/ajp.156.8.1216

Publication date: 01 August 1999

Pages1223–1229

OBJECTIVE: The purpose of this study was to describe the extent to which childhood abuse and neglect increase a person’s risk for subsequent posttraumatic stress disorder (PTSD) and to determine whether the relationship to PTSD persists despite controls ...

https://doi.org/10.1176/ajp.156.8.1223

Publication date: 01 August 1999

Pages1230–1236

OBJECTIVE: This study sought to determine how comorbidity of psychiatric and substance abuse disorders affects the likelihood of using mental health services. METHOD: The analysis was based on data on adults aged 18–54 years in the National Comorbidity ...

https://doi.org/10.1176/ajp.156.8.1230

Publication date: 01 August 1999

Pages1237–1243

OBJECTIVE: Previous research has demonstrated a greater-than-expected association between social phobia and alcohol use disorders. The purpose of this study was to test the hypothesis that drinking alcohol reduces social phobic anxiety. METHOD: Treatment-...

https://doi.org/10.1176/ajp.156.8.1237

Publication date: 01 August 1999

Pages1244–1249

OBJECTIVE: This clinical study was devised to elucidate the behaviors, motivations, and psychopathology of stalkers. METHOD: It concerned 145 stalkers referred to a forensic psychiatry center for treatment. RESULTS: Most of the stalkers were men (79%, N=...

https://doi.org/10.1176/ajp.156.8.1244

Publication date: 01 August 1999

Pages1250–1257

OBJECTIVE: Concern over rising health care costs has put pressure on providers to reduce costs, purportedly by reducing inpatient care and increasing outpatient care. METHOD: Inpatient and outpatient claims were analyzed for adult users of mental health ...

https://doi.org/10.1176/ajp.156.8.1250

Clinical Case Conference

Images In Psychiatry

Brief Report

Publication date: 01 August 1999

Pages1264–1266

OBJECTIVE: The authors investigated the relationship between number of lifetime episodes of affective disorder and the antimanic response to lithium, divalproex, or placebo. METHOD: The subjects were 154 of the 179 inpatients with acute mania who entered ...

https://doi.org/10.1176/ajp.156.8.1264

Publication date: 01 August 1999

Pages1267–1269

OBJECTIVE: This study retrospectively examined the occurrence of bipolar disorder in patients with prelingual deafness who were hospitalized for a psychiatric disorder. METHOD: The hospital charts since 1983 of all psychiatrically admitted deaf patients ...

https://doi.org/10.1176/ajp.156.8.1267

Publication date: 01 August 1999

Pages1270–1272

OBJECTIVE: This study was conducted to determine serum lipid level changes in patients who received clozapine or haloperidol. METHOD: Medical records of 222 inpatients treated with clozapine or haloperidol were reviewed. Age, weight, gender, daily ...

https://doi.org/10.1176/ajp.156.8.1270

Publication date: 01 August 1999

Pages1273–1275

OBJECTIVE: Catechol O-methyltransferase (COMT) is involved in the degradation of catecholamine neurotransmitters. Recent linkage studies of schizophrenia and molecular studies of velocardiofacial syndrome suggest that the COMT gene might be a candidate ...

https://doi.org/10.1176/ajp.156.8.1273

Publication date: 01 August 1999

Pages1276–1278

OBJECTIVE: This study compares demographic and clinical characteristics of 52 individuals with schizophrenia or schizoaffective disorder who had attempted suicide with those of 104 individuals with schizophrenia or schizoaffective disorder who had not ...

https://doi.org/10.1176/ajp.156.8.1276

Publication date: 01 August 1999

Pages1279–1281

OBJECTIVE: Tetrabenazine, a monoamine depleter and dopamine receptor blocker, is used to treat several hyperkinetic movement disorders. The authors studied the use of tetrabenazine for tardive dyskinesia. METHOD: Twenty patients with tardive dyskinesia (...

https://doi.org/10.1176/ajp.156.8.1279

Book Forum: GERIATRIC PSYCHIATRY

Book Forum: CHILD PSYCHIATRY

Book Forum: SCHIZOPHRENIA

Book Forum: ADDICTIVE DISORDERS

Letter to the Editor

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