American Journal of Psychiatry
- Volume 156
- Number 8
- August 1999
Editorial
Images In Neuroscience
Special
Publication date: 01 August 1999
Pages1138–1148OBJECTIVE: Patients with concurrent schizophrenic and mood symptoms are often treated with antipsychotics plus antidepressant or thymoleptic drugs. The authors review the literature on treatment of two overlapping groups of patients: those with ...
https://doi.org/10.1176/ajp.156.8.1138Regular Article
Publication date: 01 August 1999
Pages1149–1158OBJECTIVE: Sleep deprivation has been shown to have an antidepressant benefit in a subgroup of depressed patients. Functional imaging studies by the authors and others have suggested that patients with elevated metabolic rates in the anterior cingulate ...
https://doi.org/10.1176/ajp.156.8.1149Publication date: 01 August 1999
Pages1159–1163OBJECTIVE: Anomalous cerebral asymmetry in schizophreniform disorders has been described, but its presence in psychotic mood disorders has not been established. Measures of cerebral asymmetry may distinguish patients with psychotic mood disorders from ...
https://doi.org/10.1176/ajp.156.8.1159Publication date: 01 August 1999
Pages1164–1169OBJECTIVE: Case series and follow-up studies suggest that clozapine may have mood-stabilizing properties in addition to antipsychotic action in patients with schizoaffective disorder, bipolar type, and bipolar I disorder, but the generalizability of these ...
https://doi.org/10.1176/ajp.156.8.1164Publication date: 01 August 1999
Pages1170–1176OBJECTIVE: Fluoxetine has been associated with weight loss during acute treatment, but no controlled studies of weight change during long-term treatment with fluoxetine or other selective serotonin reuptake inhibitors have been reported. Weights were ...
https://doi.org/10.1176/ajp.156.8.1170Publication date: 01 August 1999
Pages1177–1181OBJECTIVE: This study compared the long-term efficacy of two fixed plasma levels of nortriptyline in preventing or delaying recurrence of major depression in elderly patients and in minimizing residual depressive symptoms and somatic complaints. METHOD: ...
https://doi.org/10.1176/ajp.156.8.1177Publication date: 01 August 1999
Pages1182–1189OBJECTIVE: The purpose of this study was to determine the prognosis of depression in elderly community and primary care populations. METHOD: Medline and PsycINFO were searched for potentially relevant articles published from January 1981 to November 1996 ...
https://doi.org/10.1176/ajp.156.8.1182Publication date: 01 August 1999
Pages1190–1199OBJECTIVE: In an exploration of the schizophrenia spectrum, the authors compared thalamic size, shape, and metabolic activity in unmedicated patients with schizophrenia and schizotypal personality disorder to findings in age- and sex-matched healthy ...
https://doi.org/10.1176/ajp.156.8.1190Publication date: 01 August 1999
Pages1200–1204OBJECTIVE: For many years, it has been assumed that medications affect brain chemistry and physiology but not structure. Recent reports suggest that neuroleptic medication changes basal ganglia volume. To explore this possibility, the authors assessed for ...
https://doi.org/10.1176/ajp.156.8.1200Publication date: 01 August 1999
Pages1205–1208OBJECTIVE: The authors examined phospholipids and high-energy phosphorus metabolism in the temporal lobes of drug-naive schizophrenic patients. METHOD: In vivo 31P magnetic resonance spectroscopy was performed on 17 first-episode, drug-naive schizophrenic ...
https://doi.org/10.1176/ajp.156.8.1205Publication date: 01 August 1999
Pages1209–1215OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a highly prevalent childhood psychiatric disorder characterized by impaired attention, excessive motor activity, and impulsivity. Despite extensive investigation of the neuropathophysiology of ...
https://doi.org/10.1176/ajp.156.8.1209Publication date: 01 August 1999
Pages1216–1222OBJECTIVE: Impaired neuropsychological performance involving abstraction-flexibility, memory, motor function, and attention has frequently been reported in schizophrenia as well as in attention deficit hyperactivity disorder (ADHD). This study represents ...
https://doi.org/10.1176/ajp.156.8.1216Publication date: 01 August 1999
Pages1223–1229OBJECTIVE: The purpose of this study was to describe the extent to which childhood abuse and neglect increase a person’s risk for subsequent posttraumatic stress disorder (PTSD) and to determine whether the relationship to PTSD persists despite controls ...
https://doi.org/10.1176/ajp.156.8.1223Publication date: 01 August 1999
Pages1230–1236OBJECTIVE: This study sought to determine how comorbidity of psychiatric and substance abuse disorders affects the likelihood of using mental health services. METHOD: The analysis was based on data on adults aged 18–54 years in the National Comorbidity ...
https://doi.org/10.1176/ajp.156.8.1230Publication date: 01 August 1999
Pages1237–1243OBJECTIVE: Previous research has demonstrated a greater-than-expected association between social phobia and alcohol use disorders. The purpose of this study was to test the hypothesis that drinking alcohol reduces social phobic anxiety. METHOD: Treatment-...
https://doi.org/10.1176/ajp.156.8.1237Publication date: 01 August 1999
Pages1244–1249OBJECTIVE: This clinical study was devised to elucidate the behaviors, motivations, and psychopathology of stalkers. METHOD: It concerned 145 stalkers referred to a forensic psychiatry center for treatment. RESULTS: Most of the stalkers were men (79%, N=...
https://doi.org/10.1176/ajp.156.8.1244Publication date: 01 August 1999
Pages1250–1257OBJECTIVE: Concern over rising health care costs has put pressure on providers to reduce costs, purportedly by reducing inpatient care and increasing outpatient care. METHOD: Inpatient and outpatient claims were analyzed for adult users of mental health ...
https://doi.org/10.1176/ajp.156.8.1250Clinical Case Conference
Images In Psychiatry
Brief Report
Publication date: 01 August 1999
Pages1264–1266OBJECTIVE: The authors investigated the relationship between number of lifetime episodes of affective disorder and the antimanic response to lithium, divalproex, or placebo. METHOD: The subjects were 154 of the 179 inpatients with acute mania who entered ...
https://doi.org/10.1176/ajp.156.8.1264Publication date: 01 August 1999
Pages1267–1269OBJECTIVE: This study retrospectively examined the occurrence of bipolar disorder in patients with prelingual deafness who were hospitalized for a psychiatric disorder. METHOD: The hospital charts since 1983 of all psychiatrically admitted deaf patients ...
https://doi.org/10.1176/ajp.156.8.1267Publication date: 01 August 1999
Pages1270–1272OBJECTIVE: This study was conducted to determine serum lipid level changes in patients who received clozapine or haloperidol. METHOD: Medical records of 222 inpatients treated with clozapine or haloperidol were reviewed. Age, weight, gender, daily ...
https://doi.org/10.1176/ajp.156.8.1270Publication date: 01 August 1999
Pages1273–1275OBJECTIVE: Catechol O-methyltransferase (COMT) is involved in the degradation of catecholamine neurotransmitters. Recent linkage studies of schizophrenia and molecular studies of velocardiofacial syndrome suggest that the COMT gene might be a candidate ...
https://doi.org/10.1176/ajp.156.8.1273Publication date: 01 August 1999
Pages1276–1278OBJECTIVE: This study compares demographic and clinical characteristics of 52 individuals with schizophrenia or schizoaffective disorder who had attempted suicide with those of 104 individuals with schizophrenia or schizoaffective disorder who had not ...
https://doi.org/10.1176/ajp.156.8.1276Publication date: 01 August 1999
Pages1279–1281OBJECTIVE: Tetrabenazine, a monoamine depleter and dopamine receptor blocker, is used to treat several hyperkinetic movement disorders. The authors studied the use of tetrabenazine for tardive dyskinesia. METHOD: Twenty patients with tardive dyskinesia (...
https://doi.org/10.1176/ajp.156.8.1279