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American Journal of Psychiatry

  • Volume 162
  • Number 11
  • November 2005

In This Issue

Editorial

Reviews and Overviews

Publication date: 01 November 2005

Pages1996–2021

OBJECTIVE: The authors systematically reviewed the literature on psychological approaches to treating the neuropsychiatric symptoms of dementia. METHOD: Reports of studies that examined effects of any therapy derived from a psychological approach that ...

https://doi.org/10.1176/appi.ajp.162.11.1996

Publication date: 01 November 2005

Pages2022–2030

OBJECTIVE: The authors reviewed studies published between 1990 and 2003 that reported the prevalence, incidence, and persistence of, as well as the risk factors associated with, psychosis of Alzheimer’s disease. METHOD: PubMed and PsycINFO databases were ...

https://doi.org/10.1176/appi.ajp.162.11.2022

Introspections

Clinical Case Conference

Images in Psychiatry

Presidential Paper

Article

Publication date: 01 November 2005

Pages2049–2060

OBJECTIVE: The purpose of the study was to develop a strategy for functional imaging of neurodegenerative disorders that overcomes confounds associated with differential performance between patient and comparison groups. METHOD: Functional magnetic ...

https://doi.org/10.1176/appi.ajp.162.11.2049

Publication date: 01 November 2005

Pages2061–2070

OBJECTIVE: Age-associated cholinergic dysfunction may contribute to the cognitive decline observed during aging, including a decline in working memory. The current study was designed to determine how healthy aging influences the neural response to working ...

https://doi.org/10.1176/appi.ajp.162.11.2061

Publication date: 01 November 2005

Pages2071–2077

OBJECTIVE: “Mild cognitive impairment” refers to cognitive deficits in older age that exceed age-related cognitive decline but do not fulfill criteria for dementia. Affected subjects are assumed to be at higher risk for the development of dementia, such ...

https://doi.org/10.1176/appi.ajp.162.11.2071

Publication date: 01 November 2005

Pages2078–2085

OBJECTIVE: Subcortical ischemic vascular lesions, which are closely related to small vessel disease, are a common substrate of cognitive impairment and dementia. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (...

https://doi.org/10.1176/appi.ajp.162.11.2078

Publication date: 01 November 2005

Pages2086–2093

OBJECTIVE: This study examined the frequency of major and minor depression in Alzheimer’s disease and determined whether these types of depression have a different functional and psychopathological impact and whether there is a change in the prevalence of ...

https://doi.org/10.1176/appi.ajp.162.11.2086

Publication date: 01 November 2005

Pages2094–2100

OBJECTIVE: The right to vote can be abrogated when persons become incompetent to cast a ballot. This applies particularly to people with Alzheimer’s disease, who at some point will lose capacity. A 2001 federal court decision offered the first clear ...

https://doi.org/10.1176/appi.ajp.162.11.2094

Publication date: 01 November 2005

Pages2109–2115

OBJECTIVE: Converging evidence implicates prefrontal circuits in the pathophysiology of bipolar disorder. Proton spectroscopy studies performed in adult bipolar patients assessing prefrontal regions have suggested decreased levels of N-acetylaspartate (...

https://doi.org/10.1176/appi.ajp.162.11.2109

Publication date: 01 November 2005

Pages2116–2124

OBJECTIVE: Major depression is a major risk factor for suicide. However, not all individuals with major depression commit suicide. Impulsive and aggressive behaviors have been proposed as risk factors for suicide, but it remains unclear whether their ...

https://doi.org/10.1176/appi.ajp.162.11.2116

Publication date: 01 November 2005

Pages2125–2130

OBJECTIVE: Depression is a potential risk factor for morbidity and mortality among patients with numerous medical conditions, including HIV disease, and it is also associated with decrements in immune function, such as natural killer (NK) cell activity. ...

https://doi.org/10.1176/appi.ajp.162.11.2125

Publication date: 01 November 2005

Pages2131–2138

OBJECTIVE: This study assessed the efficacy of 1) matching patients to treatments and 2) adding additional family therapy or cognitive therapy in a group of recently discharged patients with major depression. METHOD: Patients with major depression were ...

https://doi.org/10.1176/appi.ajp.162.11.2131

Publication date: 01 November 2005

Pages2139–2145

OBJECTIVE: Depressive symptoms are associated with an increased risk of cardiac events in patients with heart disease. Elevated catecholamine levels may contribute to this association, but whether depressive symptoms are associated with catecholamine ...

https://doi.org/10.1176/appi.ajp.162.11.2139

Publication date: 01 November 2005

Pages2146–2151

OBJECTIVE: This study estimated the proportion of patients attending an urban general medical practice with current major depression and a history of bipolar disorder and compared the history, presentation, and treatment of patients with unipolar and ...

https://doi.org/10.1176/appi.ajp.162.11.2146

Publication date: 01 November 2005

Pages2152–2161

OBJECTIVE: The authors tested the hypothesis that divalproex would be more effective than lithium in the long-term management of patients with recently stabilized rapid-cycling bipolar disorder. METHOD: A 20-month, double-blind, parallel-group comparison ...

https://doi.org/10.1176/appi.ajp.162.11.2152

Publication date: 01 November 2005

Pages2162–2170

OBJECTIVE: Lithium has been used during pregnancy for more than four decades, but quantification of fetal lithium exposure and clinical correlations of such exposure are limited. The study objectives were to 1) quantify the rate of lithium placental ...

https://doi.org/10.1176/appi.ajp.162.11.2162

Brief Report

Publication date: 01 November 2005

Pages2171–2173

OBJECTIVE: Neuropsychological studies of major depressive disorder have described attentional biases for affectively laden stimuli, but these reports were based on measures obtained from medicated subjects. This study investigated performance of ...

https://doi.org/10.1176/appi.ajp.162.11.2171

Publication date: 01 November 2005

Pages2173–2175

OBJECTIVE: The authors’ goal was to examine the incidence and predictors of emergent suicidality that occurred during a clinical trial of psychotherapy for adolescent depression. METHOD: The rates and predictors of emergent suicidality in 88 medication-...

https://doi.org/10.1176/appi.ajp.162.11.2173

Publication date: 01 November 2005

Pages2175–2177

OBJECTIVE: The authors used confirmatory factor analysis to replicate earlier findings that complicated grief, depression, and anxiety are distinct syndromes. METHOD: Data were derived from 1,321 bereaved individuals. Complicated grief was measured with ...

https://doi.org/10.1176/appi.ajp.162.11.2175

Publication date: 01 November 2005

Pages2178–2180

OBJECTIVE: This report examined suicidal behavior during bereavement. METHOD: Suicidal ideation was examined in a group of 60 recently bereaved widows and widowers compared to 60 individually matched married comparison subjects. RESULTS: Suicidal ideation ...

https://doi.org/10.1176/appi.ajp.162.11.2178

Publication date: 01 November 2005

Pages2180–2182

OBJECTIVE: The authors’ goal was to evaluate whether suicide attempters’ reaction to surviving their attempt predicted eventual suicide. METHOD: Three hundred ninety-three suicide attempters were categorized on the basis of their reaction to having ...

https://doi.org/10.1176/appi.ajp.162.11.2180

Publication date: 01 November 2005

Pages2182–2184

OBJECTIVE: Autism is a neurodevelopmental disorder with childhood onset and a known major genetic component. A recent study identified a highly significant association between autism and a two-single-nucleotide-polymorphism haplotype in the SLC25A12 gene, ...

https://doi.org/10.1176/appi.ajp.162.11.2182

Publication date: 01 November 2005

Pages2184–2188

OBJECTIVE: The authors’ goal was to examine the prevalence of impulse control disorders in psychiatric inpatients. METHOD: They used the Minnesota Impulsive Disorders Interview, a semistructured clinical interview assessing pathological gambling, ...

https://doi.org/10.1176/appi.ajp.162.11.2184

Publication date: 01 November 2005

Pages2188–2190

OBJECTIVE: Despite evidence of potential psychiatric sequelae following peacekeeping operations, no data have appeared on treatment outcome for this population. This study examined intake and treatment outcome data for a group of peacekeepers with ...

https://doi.org/10.1176/appi.ajp.162.11.2188

Letter to the Editor

Book Forum: GENETICS AND NEUROSCIENCE

Book Forum: PROFESSIONAL ISSUES IN PSYCHOLOGY

Book Forum: LAW AND ETHICS

Book Forum: SCHIZOPHRENIA

Correction

Official Actions

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