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American Journal of Psychiatry

  • Volume 170
  • Number 11
  • November 2013

In This Issue

Perspectives

Editorials

Perspectives

Commentary

Perspectives

Treatment in Psychiatry

Publication date: 01 November 2013

Pages1240–1247

Objective Little information is available on the need for dosage changes for lamotrigine in pregnant women with bipolar disorder. The authors present new data on serial serum levels of lamotrigine in pregnant patients on lamotrigine monotherapy. They also ...

https://doi.org/10.1176/appi.ajp.2013.13010006

Perspectives

Images in Psychiatry

Perspectives

Reviews and Overviews

The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders

Publication date: 01 November 2013

Pages1249–1262

A task force report presents 12 recommendations for antidepressant use in bipolar disorder rated by at least 80% of International Society for Bipolar Disorders experts as essential or important.

https://doi.org/10.1176/appi.ajp.2013.13020185

New Research

Articles

Publication date: 01 November 2013

Pages1263–1274

Objective Developing categorical diagnoses that have biological meaning within the clinical phenotype of psychosis (schizophrenia, schizoaffective disorder, and bipolar I disorder with psychosis) is as important for developing targeted treatments as for ...

https://doi.org/10.1176/appi.ajp.2013.12101339

Publication date: 01 November 2013

Pages1308–1316

Objective The authors sought to explore whether anatomical and functional brain deficits are present in similar or different brain regions early in the course of schizophrenia, before antipsychotic treatment, and whether these deficits are more severe or ...

https://doi.org/10.1176/appi.ajp.2013.12091148

Publication date: 01 November 2013

Pages1317–1325

Objective Several lines of evidence indicate that white matter integrity is compromised in bipolar disorder, but the nature, extent, and biological causes remain elusive. To determine the extent to which white matter deficits in bipolar disorder are ...

https://doi.org/10.1176/appi.ajp.2013.12111462

Publication date: 01 November 2013

Pages1326–1334

Objective Frontostriatal circuitry is critical to learning processes, and its disruption may underlie maladaptive decision making and the generation of psychotic symptoms in schizophrenia. However, there is a paucity of evidence directly examining the role ...

https://doi.org/10.1176/appi.ajp.2013.12070978

Publication date: 01 November 2013

Pages1335–1344

Placebo response has increased over the past few decades, and this temporal effect is explained by an increase of the number of sites per trial and by a decrease in the number of academic sites in randomized controlled trials.

https://doi.org/10.1176/appi.ajp.2013.12030315

Publication date: 01 November 2013

Pages1356–1363

Objective Substance-dependent individuals make poor decisions on the Iowa Gambling Task, a reward-related decision-making task that involves risk and uncertainty. Task performance depends on several factors, including how sensitive individuals are to ...

https://doi.org/10.1176/appi.ajp.2013.12091257

Communications and Updates

Letters to the Editor

Communications and Updates

Book Forum

Correction

Communications and Updates

Books Received

Past Issues

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