American Journal of Psychiatry
- Volume 170
- Number 11
- November 2013
In This Issue
Perspectives
Editorials
Perspectives
Commentary
Perspectives
Treatment in Psychiatry
Publication date: 01 November 2013
Pages1240–1247ObjectiveLittle information is available on the need for dosage changes for lamotrigine in pregnant women with bipolar disorder. The authors present new data on serial serum levels of lamotrigine in pregnant patients on lamotrigine monotherapy. They also ...
https://doi.org/10.1176/appi.ajp.2013.13010006Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 November 2013
Pages1249–1262A task force report presents 12 recommendations for antidepressant use in bipolar disorder rated by at least 80% of International Society for Bipolar Disorders experts as essential or important.
https://doi.org/10.1176/appi.ajp.2013.13020185New Research
Articles
Publication date: 01 November 2013
Pages1263–1274ObjectiveDeveloping categorical diagnoses that have biological meaning within the clinical phenotype of psychosis (schizophrenia, schizoaffective disorder, and bipolar I disorder with psychosis) is as important for developing targeted treatments as for ...
https://doi.org/10.1176/appi.ajp.2013.12101339Publication date: 01 November 2013
Pages1275–1284ObjectiveFamilial neuropsychological deficits are well established in schizophrenia but remain less well characterized in other psychotic disorders. This study from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) consortium 1) ...
https://doi.org/10.1176/appi.ajp.2013.12101298Publication date: 01 November 2013
Pages1285–1296ObjectiveThe study examined gray matter volume across psychosis diagnoses organized by dimensional and DSM-IV categories from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) sample.MethodIn total, 351 probands with psychosis (146 ...
https://doi.org/10.1176/appi.ajp.2013.13010126Publication date: 01 November 2013
Pages1297–1307Increased activation of the dorsolateral prefrontal cortex region during working memory manipulation is a compensatory mechanism in at-risk individuals.
https://doi.org/10.1176/appi.ajp.2013.12081135Publication date: 01 November 2013
Pages1308–1316ObjectiveThe authors sought to explore whether anatomical and functional brain deficits are present in similar or different brain regions early in the course of schizophrenia, before antipsychotic treatment, and whether these deficits are more severe or ...
https://doi.org/10.1176/appi.ajp.2013.12091148Publication date: 01 November 2013
Pages1317–1325ObjectiveSeveral lines of evidence indicate that white matter integrity is compromised in bipolar disorder, but the nature, extent, and biological causes remain elusive. To determine the extent to which white matter deficits in bipolar disorder are ...
https://doi.org/10.1176/appi.ajp.2013.12111462Publication date: 01 November 2013
Pages1326–1334ObjectiveFrontostriatal circuitry is critical to learning processes, and its disruption may underlie maladaptive decision making and the generation of psychotic symptoms in schizophrenia. However, there is a paucity of evidence directly examining the role ...
https://doi.org/10.1176/appi.ajp.2013.12070978Publication date: 01 November 2013
Pages1335–1344Placebo response has increased over the past few decades, and this temporal effect is explained by an increase of the number of sites per trial and by a decrease in the number of academic sites in randomized controlled trials.
https://doi.org/10.1176/appi.ajp.2013.12030315Publication date: 01 November 2013
Pages1345–1355Nonresponding patients activated a circuit that suggested danger in response to a safety signal, so cognitive exposure appears to partially reinforce rather than diminish the feeling of danger through a misinterpretation of the safety signal.
https://doi.org/10.1176/appi.ajp.2013.12111484Publication date: 01 November 2013
Pages1356–1363ObjectiveSubstance-dependent individuals make poor decisions on the Iowa Gambling Task, a reward-related decision-making task that involves risk and uncertainty. Task performance depends on several factors, including how sensitive individuals are to ...
https://doi.org/10.1176/appi.ajp.2013.12091257Communications and Updates
Letters to the Editor
Communications and Updates
Book Forum
Correction
Communications and Updates
Books Received
Past Issues
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