American Journal of Psychiatry
- Volume 158
- Number 9
- September 2001
Editorial
Reviews and Overviews
Publication date: 01 September 2001
Pages1367–1377OBJECTIVE: Research has implicated dysfunction of glutamatergic neurotransmission in the pathophysiology of schizophrenia. This review evaluates evidence from preclinical and clinical studies that brain glutamatergic neurotransmission is altered in ...
https://doi.org/10.1176/appi.ajp.158.9.1367Publication date: 01 September 2001
Pages1378–1383OBJECTIVE: Psychiatrists are under immense ethical pressure when practicing in circumstances that reasonable, informed colleagues would regard as not “good enough” in that they do not adequately meet the needs of patients and patients’ families. This ...
https://doi.org/10.1176/appi.ajp.158.9.1378Images in Neuroscience
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 September 2001
Pages1393–1399OBJECTIVE: Recent investigations of schizophrenia have targeted glutamatergic neurotransmission, since phencyclidine, an N-methyl-d-aspartate (NMDA) receptor antagonist, can induce schizophreniform psychosis. The authors previously reported alterations in ...
https://doi.org/10.1176/appi.ajp.158.9.1393Publication date: 01 September 2001
Pages1400–1410OBJECTIVE: The N-methyl-d-aspartic acid (NMDA) class of glutamate receptors has received attention in the pathophysiology of schizophrenia because of the similarity between some schizophrenic symptoms and symptoms caused by NMDA antagonists. To determine ...
https://doi.org/10.1176/appi.ajp.158.9.1400Publication date: 01 September 2001
Pages1411–1422OBJECTIVE: Neuronal number in the mediodorsal thalamic nucleus, the principal source of thalamic projections to the prefrontal cortex, has been reported to be lower in subjects with schizophrenia. The authors tested the hypothesis that schizophrenia is ...
https://doi.org/10.1176/appi.ajp.158.9.1411Publication date: 01 September 2001
Pages1423–1428OBJECTIVE: The authors examined brain activity associated with the internal monitoring of performance to test the hypothesis that error-related activity in the anterior cingulate cortex is impaired in patients with schizophrenia. METHOD: Seventeen ...
https://doi.org/10.1176/appi.ajp.158.9.1423Publication date: 01 September 2001
Pages1429–1436OBJECTIVE: The authors sought to identify brain mechanisms underlying the well-documented facial affect recognition deficit in patients with schizophrenia. Since this deficit is stable over the course of the illness and relatively specific for ...
https://doi.org/10.1176/appi.ajp.158.9.1429Publication date: 01 September 2001
Pages1437–1440OBJECTIVE: Dichotic listening techniques have been used to study hemispheric dominance for language in schizophrenia. The authors’ goal was to compare subjects with paranoid and undifferentiated subtypes of schizophrenia. METHOD: The Fused Rhymed Words ...
https://doi.org/10.1176/appi.ajp.158.9.1437Publication date: 01 September 2001
Pages1441–1448OBJECTIVE: Follow-up studies of cognitive functions of poor-outcome (long-term institutionalized) elderly patients with schizophrenia have demonstrated deterioration over time, while stable cognitive functions over time have been reported for younger, ...
https://doi.org/10.1176/appi.ajp.158.9.1441Publication date: 01 September 2001
Pages1449–1454OBJECTIVE: The assumption that psychotic patients assigned to placebo in clinical trials of antipsychotics are exposed to substantial morbidity and mortality is not based on data about what actually happens to such patients. This study assesses symptoms ...
https://doi.org/10.1176/appi.ajp.158.9.1449Publication date: 01 September 2001
Pages1455–1460OBJECTIVE: Binge eating disorder was introduced in DSM-IV as a psychiatric disorder needing further study. This community-based study describes the relationship between race and clinical functioning in black and white women with and without binge eating ...
https://doi.org/10.1176/appi.ajp.158.9.1455Publication date: 01 September 2001
Pages1461–1466OBJECTIVE: This study reported pregnancy complications and neonatal outcomes for 49 live births in a group of women with eating disorders who were prospectively followed. METHOD: Subjects were recruited from 246 women participating in a longitudinal study ...
https://doi.org/10.1176/appi.ajp.158.9.1461Publication date: 01 September 2001
Pages1467–1473OBJECTIVE: Reliance on the categorical model of psychiatric disorders has led to neglected study of posttraumatic sequelae that fall short of full criteria for posttraumatic stress disorder (PTSD). Substantial disability and suicidal risk is associated ...
https://doi.org/10.1176/appi.ajp.158.9.1467Publication date: 01 September 2001
Pages1474–1479OBJECTIVE: The authors examined the longitudinal changes in posttraumatic stress disorder (PTSD) symptom levels and prevalence rates over a 4-year time period among American former prisoners of war (POWs) from World War II and the Korean War. ...
https://doi.org/10.1176/appi.ajp.158.9.1474Publication date: 01 September 2001
Pages1480–1485OBJECTIVE: Meeting criterion A2 for the diagnosis of posttraumatic stress disorder (PTSD) in DSM-IV requires that an individual have high levels of distress during or after the traumatic event. Because of the paucity of valid and reliable instruments for ...
https://doi.org/10.1176/appi.ajp.158.9.1480Publication date: 01 September 2001
Pages1486–1491OBJECTIVE: Women have higher rates of posttraumatic stress disorder (PTSD) than men. The authors examined prior trauma, PTSD, major depression, anxiety disorder not including PTSD, and peritraumatic dissociation; current peritraumatic dissociation; and ...
https://doi.org/10.1176/appi.ajp.158.9.1486Publication date: 01 September 2001
Pages1492–1499OBJECTIVE: There is growing interest in distinguishing the biological bases of sex differences in behavior from environmental influences. Sex hormone levels seem to be related to some cognitive abilities, particularly memory, and the dopaminergic system ...
https://doi.org/10.1176/appi.ajp.158.9.1492Publication date: 01 September 2001
Pages1500–1505OBJECTIVE: The characteristics of male and female gamblers utilizing a gambling helpline were examined to identify gender-related differences. METHOD: The authors performed logistic regression analyses on data obtained in 1998–1999 from callers to a ...
https://doi.org/10.1176/appi.ajp.158.9.1500Brief Report
Publication date: 01 September 2001
Pages1506–1508OBJECTIVE: The effects of a treatment program targeting debilitating grief symptoms were tested in a pilot study. METHOD: Twenty-one individuals experiencing traumatic grief were recruited for participation, and 13 completed the full 4-month protocol. The ...
https://doi.org/10.1176/appi.ajp.158.9.1506Publication date: 01 September 2001
Pages1509–1511OBJECTIVE: This study assessed the relationship between posttraumatic stress symptoms and salivary cortisol levels after a severe ice storm. METHOD: Posttraumatic stress symptoms (Impact of Event Scale scores) and salivary cortisol levels were determined ...
https://doi.org/10.1176/appi.ajp.158.9.1509Publication date: 01 September 2001
Pages1511–1514OBJECTIVE: The authors’ goal was to conduct a double-blind trial of vitamin B6 in the treatment of tardive dyskinesia in patients with schizophrenia. METHOD: Fifteen inpatients with schizophrenia who met research diagnostic criteria for tardive dyskinesia ...
https://doi.org/10.1176/appi.ajp.158.9.1511Publication date: 01 September 2001
Pages1514–1516OBJECTIVE: Preclinical evidence exists for the anxiolytic activity of atrial natriuretic peptide, which is released during lactate-induced panic attacks. Atrial natriuretic peptide receptor modulation may have antipanic activity in patients with panic ...
https://doi.org/10.1176/appi.ajp.158.9.1514Publication date: 01 September 2001
Pages1517–1519OBJECTIVE: Age-related decrease in dopamine D2 receptors is associated with cognitive decline in healthy elderly individuals. This study was an investigation of whether the dopamine receptor agonist piribedil improves global cognitive function in patients ...
https://doi.org/10.1176/appi.ajp.158.9.1517Publication date: 01 September 2001
Pages1519–1521OBJECTIVE: The authors examined trends in the prevalence of substance use and its relationship to attributes of life style among college students over a 30-year period. METHOD: They distributed anonymous questionnaires to 796 seniors at a large New ...
https://doi.org/10.1176/appi.ajp.158.9.1519Publication date: 01 September 2001
Pages1521–1524OBJECTIVE: It is established that patients with bipolar disorder have an excess of births in winter or early spring. The authors investigated a link between season of birth and white matter lesions with magnetic resonance imaging (MRI). METHOD: T2-...
https://doi.org/10.1176/appi.ajp.158.9.1521Publication date: 01 September 2001
Pages1524–1526OBJECTIVE: The characteristics of patients who cycle from mania to major depression and the frequencies of these cycles remain poorly understood. METHOD: This study compared 28 patients with a first episode of mania who cycled into a major depressive ...
https://doi.org/10.1176/appi.ajp.158.9.1524Letter to the Editor
Book Forum: Psychopharmacology
Book Forum: Alternative Medicine
Book Forum: Cultural and Ethnic Issues
Book Forum: Sleep and Dreaming
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