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American Journal of Psychiatry

  • Volume 160
  • Number 12
  • December 2003

In This Issue

Editorial

Reviews and Overviews

Publication date: 01 December 2003

Pages2080–2090

OBJECTIVE: The authors systematically evaluated the published evidence to assess the effectiveness of disease management programs in depression. METHOD: English-language articles on depression were identified through a MEDLINE search for the period from ...

https://doi.org/10.1176/appi.ajp.160.12.2080

Images in Neuroscience

Introspections

Clinical Case Conference

Images in Psychiatry

Article

Publication date: 01 December 2003

Pages2099–2107

OBJECTIVE: Since improved prediction of illness course early in bipolar disorder is required to guide treatment planning, the authors evaluated recovery, first recurrence, and new illness onset following first hospitalization for mania. METHOD: Bipolar ...

https://doi.org/10.1176/appi.ajp.160.12.2099

Publication date: 01 December 2003

Pages2108–2115

OBJECTIVE: The authors examined the clinical characteristics and 48-month illness course of cases of nonaffective acute remitting psychosis and described the classification of these cases in the DSM-IV system. METHOD: The data were derived from the ...

https://doi.org/10.1176/appi.ajp.160.12.2108

Publication date: 01 December 2003

Pages2116–2121

OBJECTIVE: The goal of this study was to predict the onset of mood and anxiety disorders from parent-reported emotional and behavioral problems in childhood across a 14-year period from childhood into young adulthood. METHOD: In 1983, parent reports of ...

https://doi.org/10.1176/appi.ajp.160.12.2116

Publication date: 01 December 2003

Pages2122–2127

OBJECTIVE: The authors investigated the impact of medical comorbidity on the acute phase of antidepressant treatment in subjects with major depressive disorder. METHOD: A total of 384 outpatients meeting DSM-III-R criteria for major depressive disorder ...

https://doi.org/10.1176/appi.ajp.160.12.2122

Publication date: 01 December 2003

Pages2128–2133

OBJECTIVE: Impairment was added as a diagnostic criterion for many psychiatric disorders in DSM-IV. Does the addition of impairment influence only prevalence rates, or does it also introduce new etiological factors into psychiatric diagnoses? METHOD: A ...

https://doi.org/10.1176/appi.ajp.160.12.2128

Publication date: 01 December 2003

Pages2134–2140

OBJECTIVE: The study aimed to explore how prevalent agitated depression is in bipolar I disorder, whether it represents a mixed state, and whether it differs from nonagitated depression with respect to course and outcome. METHOD: From 313 bipolar I ...

https://doi.org/10.1176/appi.ajp.160.12.2134

Publication date: 01 December 2003

Pages2141–2147

OBJECTIVE: The identification of predictors of major depression in the transition to adulthood has direct application to prevention and intervention efforts designed to forestall depression in this high-risk period. The current study identified childhood ...

https://doi.org/10.1176/appi.ajp.160.12.2141

Publication date: 01 December 2003

Pages2148–2153

OBJECTIVE: Schizophrenia has been reported to be associated with altered localization of regions responding to sound in the auditory cortex, suggesting possible cortical reorganization accompanying the disorder, but it is not clear whether such ...

https://doi.org/10.1176/appi.ajp.160.12.2148

Publication date: 01 December 2003

Pages2154–2168

OBJECTIVE: High-resolution magnetic resonance imaging (MRI) was used to compare cortical gray and white matter and CSF volumes in schizophrenia patients with poor outcomes, schizophrenia patients with good outcomes, and healthy comparison subjects. METHOD:...

https://doi.org/10.1176/appi.ajp.160.12.2154

Publication date: 01 December 2003

Pages2181–2189

OBJECTIVE: Previous reports have documented a striking progressive reduction in cortical gray matter volume during adolescence in patients with childhood-onset schizophrenia. This study examined the rate of loss in cortical gray matter volume in relation ...

https://doi.org/10.1176/appi.ajp.160.12.2181

Publication date: 01 December 2003

Pages2190–2197

OBJECTIVE: The authors investigated volumetric alterations of the anterior hippocampal formation in patients experiencing a first episode of schizophrenia relative to healthy comparison subjects. METHOD: From contiguous 1.5-mm coronal magnetic resonance ...

https://doi.org/10.1176/appi.ajp.160.12.2190

Publication date: 01 December 2003

Pages2198–2201

OBJECTIVE: An abnormal superior temporal gyrus has figured prominently in schizophrenia research, and left superior temporal gyrus volume has been shown to be smaller in male subjects with schizotypal personality disorder. This is the first structural ...

https://doi.org/10.1176/appi.ajp.160.12.2198

Publication date: 01 December 2003

Pages2202–2208

OBJECTIVE: The influential 1972 study by Manfred Bleuler on the long-term course of schizophrenic illness has been reconsidered. The authors tested the diagnosis of schizophrenia in all patients and investigated how the distribution of the types of ...

https://doi.org/10.1176/appi.ajp.160.12.2202

Publication date: 01 December 2003

Pages2209–2215

OBJECTIVE: Numerous neuroimaging studies have examined the function of the dorsolateral prefrontal cortex in schizophrenia; although abnormalities usually are identified, it is unclear why some studies find too little activation and others too much. The ...

https://doi.org/10.1176/appi.ajp.160.12.2209

Publication date: 01 December 2003

Pages2216–2221

OBJECTIVE: Many case-control and cross-sectional studies have observed an association with cigarette smoking after the onset of schizophrenia, and there is evidence to suggest that smoking may improve symptoms in people with this disorder. Here, the ...

https://doi.org/10.1176/appi.ajp.160.12.2216

Publication date: 01 December 2003

Pages2222–2227

OBJECTIVE: The authors sought to determine if greater seafood consumption, a measure of omega-3 fatty acid intake, is associated with lower prevalence rates of bipolar disorder in community samples. METHOD: Lifetime prevalence rates in various countries ...

https://doi.org/10.1176/appi.ajp.160.12.2222

Brief Report

Publication date: 01 December 2003

Pages2228–2230

OBJECTIVE: Individuals with mental illness have high rates of tobacco dependence; however, little is known about what influences a psychiatrist’s decision to offer smoking-cessation counseling to smoking patients. METHOD: Using the National Ambulatory ...

https://doi.org/10.1176/appi.ajp.160.12.2228

Publication date: 01 December 2003

Pages2234–2236

OBJECTIVE: The study was an investigation of the effect of the antiviral medication valacyclovir on the symptoms of outpatients with persistent schizophrenia. METHOD: Oral valacyclovir, 1 g twice daily, was administered to 65 outpatients over 16 weeks ...

https://doi.org/10.1176/appi.ajp.160.12.2234

Publication date: 01 December 2003

Pages2236–2238

OBJECTIVE: The hypothesis of a sensory gating defect in schizophrenia has been supported by studies demonstrating deficient auditory P50 gating in patients. P50 gating is the relative attenuation of P50 amplitude in the auditory evoked potential following ...

https://doi.org/10.1176/appi.ajp.160.12.2236

Publication date: 01 December 2003

Pages2238–2240

OBJECTIVE: The authors tested whether neural synchronization deficits were present in subjects with schizophrenia and schizotypal personality disorder. METHOD: Amplitude-modulated tones were used to evaluate auditory steady-state evoked potential ...

https://doi.org/10.1176/appi.ajp.160.12.2238

Letter to the Editor

Book Forum: FICTION

Book Forum: HISTORY AND SOCIETY

Book Forum: BIOGRAPHY

Correction

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