American Journal of Psychiatry
- Volume 160
- Number 12
- December 2003
In This Issue
Editorial
Reviews and Overviews
Publication date: 01 December 2003
Pages2080–2090OBJECTIVE: The authors systematically evaluated the published evidence to assess the effectiveness of disease management programs in depression. METHOD: English-language articles on depression were identified through a MEDLINE search for the period from ...
https://doi.org/10.1176/appi.ajp.160.12.2080Images in Neuroscience
Introspections
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 December 2003
Pages2099–2107OBJECTIVE: Since improved prediction of illness course early in bipolar disorder is required to guide treatment planning, the authors evaluated recovery, first recurrence, and new illness onset following first hospitalization for mania. METHOD: Bipolar ...
https://doi.org/10.1176/appi.ajp.160.12.2099Publication date: 01 December 2003
Pages2108–2115OBJECTIVE: The authors examined the clinical characteristics and 48-month illness course of cases of nonaffective acute remitting psychosis and described the classification of these cases in the DSM-IV system. METHOD: The data were derived from the ...
https://doi.org/10.1176/appi.ajp.160.12.2108Publication date: 01 December 2003
Pages2116–2121OBJECTIVE: The goal of this study was to predict the onset of mood and anxiety disorders from parent-reported emotional and behavioral problems in childhood across a 14-year period from childhood into young adulthood. METHOD: In 1983, parent reports of ...
https://doi.org/10.1176/appi.ajp.160.12.2116Publication date: 01 December 2003
Pages2122–2127OBJECTIVE: The authors investigated the impact of medical comorbidity on the acute phase of antidepressant treatment in subjects with major depressive disorder. METHOD: A total of 384 outpatients meeting DSM-III-R criteria for major depressive disorder ...
https://doi.org/10.1176/appi.ajp.160.12.2122Publication date: 01 December 2003
Pages2128–2133OBJECTIVE: Impairment was added as a diagnostic criterion for many psychiatric disorders in DSM-IV. Does the addition of impairment influence only prevalence rates, or does it also introduce new etiological factors into psychiatric diagnoses? METHOD: A ...
https://doi.org/10.1176/appi.ajp.160.12.2128Publication date: 01 December 2003
Pages2134–2140OBJECTIVE: The study aimed to explore how prevalent agitated depression is in bipolar I disorder, whether it represents a mixed state, and whether it differs from nonagitated depression with respect to course and outcome. METHOD: From 313 bipolar I ...
https://doi.org/10.1176/appi.ajp.160.12.2134Publication date: 01 December 2003
Pages2141–2147OBJECTIVE: The identification of predictors of major depression in the transition to adulthood has direct application to prevention and intervention efforts designed to forestall depression in this high-risk period. The current study identified childhood ...
https://doi.org/10.1176/appi.ajp.160.12.2141Publication date: 01 December 2003
Pages2148–2153OBJECTIVE: Schizophrenia has been reported to be associated with altered localization of regions responding to sound in the auditory cortex, suggesting possible cortical reorganization accompanying the disorder, but it is not clear whether such ...
https://doi.org/10.1176/appi.ajp.160.12.2148Publication date: 01 December 2003
Pages2154–2168OBJECTIVE: High-resolution magnetic resonance imaging (MRI) was used to compare cortical gray and white matter and CSF volumes in schizophrenia patients with poor outcomes, schizophrenia patients with good outcomes, and healthy comparison subjects. METHOD:...
https://doi.org/10.1176/appi.ajp.160.12.2154Publication date: 01 December 2003
Pages2169–2180OBJECTIVE: The authors investigated the modulating effects of biological sex and age on regional decreases in cortical gray matter and increases in subarachnoid CSF in 25 patients with chronic schizophrenia and 28 group-matched healthy comparison ...
https://doi.org/10.1176/appi.ajp.160.12.2169Publication date: 01 December 2003
Pages2181–2189OBJECTIVE: Previous reports have documented a striking progressive reduction in cortical gray matter volume during adolescence in patients with childhood-onset schizophrenia. This study examined the rate of loss in cortical gray matter volume in relation ...
https://doi.org/10.1176/appi.ajp.160.12.2181Publication date: 01 December 2003
Pages2190–2197OBJECTIVE: The authors investigated volumetric alterations of the anterior hippocampal formation in patients experiencing a first episode of schizophrenia relative to healthy comparison subjects. METHOD: From contiguous 1.5-mm coronal magnetic resonance ...
https://doi.org/10.1176/appi.ajp.160.12.2190Publication date: 01 December 2003
Pages2198–2201OBJECTIVE: An abnormal superior temporal gyrus has figured prominently in schizophrenia research, and left superior temporal gyrus volume has been shown to be smaller in male subjects with schizotypal personality disorder. This is the first structural ...
https://doi.org/10.1176/appi.ajp.160.12.2198Publication date: 01 December 2003
Pages2202–2208OBJECTIVE: The influential 1972 study by Manfred Bleuler on the long-term course of schizophrenic illness has been reconsidered. The authors tested the diagnosis of schizophrenia in all patients and investigated how the distribution of the types of ...
https://doi.org/10.1176/appi.ajp.160.12.2202Publication date: 01 December 2003
Pages2209–2215OBJECTIVE: Numerous neuroimaging studies have examined the function of the dorsolateral prefrontal cortex in schizophrenia; although abnormalities usually are identified, it is unclear why some studies find too little activation and others too much. The ...
https://doi.org/10.1176/appi.ajp.160.12.2209Publication date: 01 December 2003
Pages2216–2221OBJECTIVE: Many case-control and cross-sectional studies have observed an association with cigarette smoking after the onset of schizophrenia, and there is evidence to suggest that smoking may improve symptoms in people with this disorder. Here, the ...
https://doi.org/10.1176/appi.ajp.160.12.2216Publication date: 01 December 2003
Pages2222–2227OBJECTIVE: The authors sought to determine if greater seafood consumption, a measure of omega-3 fatty acid intake, is associated with lower prevalence rates of bipolar disorder in community samples. METHOD: Lifetime prevalence rates in various countries ...
https://doi.org/10.1176/appi.ajp.160.12.2222Brief Report
Publication date: 01 December 2003
Pages2228–2230OBJECTIVE: Individuals with mental illness have high rates of tobacco dependence; however, little is known about what influences a psychiatrist’s decision to offer smoking-cessation counseling to smoking patients. METHOD: Using the National Ambulatory ...
https://doi.org/10.1176/appi.ajp.160.12.2228Publication date: 01 December 2003
Pages2231–2233OBJECTIVE: This in vivo 1H magnetic resonance spectroscopy study examined levels of glutamate, glutamine, and N-acetylaspartate in medicated patients with chronic schizophrenia. METHOD: Localized in vivo 1H spectra were acquired at 4.0 T from the left ...
https://doi.org/10.1176/appi.ajp.160.12.2231Reduction of Symptoms by Valacyclovir in Cytomegalovirus-Seropositive Individuals With Schizophrenia
Publication date: 01 December 2003
Pages2234–2236OBJECTIVE: The study was an investigation of the effect of the antiviral medication valacyclovir on the symptoms of outpatients with persistent schizophrenia. METHOD: Oral valacyclovir, 1 g twice daily, was administered to 65 outpatients over 16 weeks ...
https://doi.org/10.1176/appi.ajp.160.12.2234Publication date: 01 December 2003
Pages2236–2238OBJECTIVE: The hypothesis of a sensory gating defect in schizophrenia has been supported by studies demonstrating deficient auditory P50 gating in patients. P50 gating is the relative attenuation of P50 amplitude in the auditory evoked potential following ...
https://doi.org/10.1176/appi.ajp.160.12.2236Publication date: 01 December 2003
Pages2238–2240OBJECTIVE: The authors tested whether neural synchronization deficits were present in subjects with schizophrenia and schizotypal personality disorder. METHOD: Amplitude-modulated tones were used to evaluate auditory steady-state evoked potential ...
https://doi.org/10.1176/appi.ajp.160.12.2238