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American Journal of Psychiatry

  • Volume 160
  • Number 9
  • September 2003

In This Issue

Editorial

Reviews and Overviews

Publication date: 01 September 2003

Pages1554–1565

OBJECTIVE: Previous theories have emphasized the role of excessive glucocorticoid activity in the pathology of chronic stress. Nevertheless, insufficient glucocorticoid signaling (resulting from decreased hormone bioavailability or reduced hormone ...

https://doi.org/10.1176/appi.ajp.160.9.1554

Publication date: 01 September 2003

Pages1566–1577

OBJECTIVE: When there exists no single source of information (informant) to validly measure a characteristic, it is typically recommended that data from multiple informants be used. In psychiatric assessment and research, however, multiple informants ...

https://doi.org/10.1176/appi.ajp.160.9.1566

Images in Neuroscience

Images in Psychiatry

Article

Publication date: 01 September 2003

Pages1580–1586

OBJECTIVE: This study investigated the schizophrenia phenotype in 24 subjects with 22q11 deletion syndrome (22qDS) and schizophrenia (22qDS-schizophrenia), a rare but relatively homogenous genetic subtype of schizophrenia associated with a microdeletion ...

https://doi.org/10.1176/appi.ajp.160.9.1580

Publication date: 01 September 2003

Pages1587–1594

OBJECTIVE: Identification of the genetically related disorders in the putative schizophrenia spectrum is an unresolved problem. Data from the Finnish Adoptive Family Study of Schizophrenia, which was designed to disentangle genetic and environmental ...

https://doi.org/10.1176/appi.ajp.160.9.1587

Publication date: 01 September 2003

Pages1606–1613

OBJECTIVE: Although well documented, regional brain structural abnormalities in schizophrenia are nonspecific, and morphometric parameters show significant overlapping between patients and healthy comparison subjects. An increasing number of studies have ...

https://doi.org/10.1176/appi.ajp.160.9.1606

Publication date: 01 September 2003

Pages1614–1617

OBJECTIVE: The authors previously reported that men with chronic schizophrenia had a smaller vermian subregion than did healthy men. In this study, they tested whether posterior superior vermis reduction would be seen in a larger group of schizophrenia ...

https://doi.org/10.1176/appi.ajp.160.9.1614

Publication date: 01 September 2003

Pages1618–1620

OBJECTIVE: This study was designed to prospectively examine differential effects of sustained “high” and “low” serum prolactin levels on bone mineral density and peripheral markers of bone metabolism. METHOD: A dual-energy X-ray absorptiometer was used to ...

https://doi.org/10.1176/appi.ajp.160.9.1618

Publication date: 01 September 2003

Pages1621–1626

OBJECTIVE: Attentional deficits have been identified as an abnormality that individuals with schizotypal personality disorder share with schizophrenia patients. The purpose of this study was to examine automatic sensorimotor gating and controlled ...

https://doi.org/10.1176/appi.ajp.160.9.1621

Publication date: 01 September 2003

Pages1627–1635

OBJECTIVE: Methods to prevent two major mental disorders, schizophrenia and conduct disorder, have been elusive. This study assessed the effects of an early nutritional, educational, and physical exercise enrichment program on adult outcome for ...

https://doi.org/10.1176/appi.ajp.160.9.1627

Publication date: 01 September 2003

Pages1636–1642

OBJECTIVE: Utilizing data from a previously characterized registry of subjects with bipolar illness, the authors examined age at onset of the first illness episode in cohorts of subjects born from 1900 through 1939 and from 1940 through 1959. METHOD: ...

https://doi.org/10.1176/appi.ajp.160.9.1636

Publication date: 01 September 2003

Pages1643–1650

OBJECTIVE: Gender differences in antidepressant treatment response, side effects, dropout rates, and plasma concentrations were examined in patients with major and predominantly melancholic depression. METHOD: The study included a subgroup of 292 ...

https://doi.org/10.1176/appi.ajp.160.9.1643

Publication date: 01 September 2003

Pages1651–1658

OBJECTIVE: The authors compared the efficacy and safety of aripiprazole, a novel antipsychotic, to placebo for treatment of patients in an acute manic or mixed episode of bipolar disorder. METHOD: This 3-week, multicenter, double-blind study randomly ...

https://doi.org/10.1176/appi.ajp.160.9.1651

Publication date: 01 September 2003

Pages1659–1662

OBJECTIVE: This study examined the association of depression severity and drug injection HIV risk behavior among injection drug users. METHOD: Injection drug users who met the DSM-IV criteria for major depressive disorder, dysthymia, or substance-induced ...

https://doi.org/10.1176/appi.ajp.160.9.1659

Publication date: 01 September 2003

Pages1663–1669

OBJECTIVE: Building on findings about the prevalence and incidence of depression over a 40-year period, the authors provide data on trends in cigarette smoking and associations with depression. METHOD: Data come from interviews with adult population ...

https://doi.org/10.1176/appi.ajp.160.9.1663

Publication date: 01 September 2003

Pages1670–1676

OBJECTIVE: Epidemiological studies have reported an association between smoking and mental disorders. However, little is known about the impairment associated with nicotine dependence. METHOD: The authors assessed health-related quality of life, ...

https://doi.org/10.1176/appi.ajp.160.9.1670

Publication date: 01 September 2003

Pages1677–1683

OBJECTIVE: The feasibility of the 1999 voluntary, community-based National Alcohol Screening Day (NASD) was assessed by determining 1) the extent to which community and college sites were registered to hold screenings and the extent to which the subjects ...

https://doi.org/10.1176/appi.ajp.160.9.1677

Publication date: 01 September 2003

Pages1684–1690

OBJECTIVE: Community surveys have demonstrated significant psychological distress since the terrorist attacks of Sept. 11, 2001. Since people with posttraumatic stress disorder (PTSD) and other mental illnesses are especially vulnerable to stressful ...

https://doi.org/10.1176/appi.ajp.160.9.1684

Brief Report

Publication date: 01 September 2003

Pages1691–1693

OBJECTIVE: Leukocyte counts and plasma neopterin levels were determined in autistic children and matched healthy comparison subjects. METHOD: Blood from 31 autistic children and 28 age- and gender-matched healthy comparison subjects was analyzed for ...

https://doi.org/10.1176/appi.ajp.160.9.1691

Publication date: 01 September 2003

Pages1693–1696

OBJECTIVE: To examine brain-behavior relationships in attention deficit hyperactivity disorder (ADHD), the authors obtained magnetic resonance imaging (MRI) scans of monozygotic twins discordant for ADHD. METHOD: National recruitment was followed by in-...

https://doi.org/10.1176/appi.ajp.160.9.1693

Publication date: 01 September 2003

Pages1696–1698

OBJECTIVE: Comorbid bipolar and panic disorders aggregate in families. A phenotypic trait shared by both disorders is the sudden shift in affect observed in panic attacks and some rapid cycling states. The authors investigated whether comorbidity of ...

https://doi.org/10.1176/appi.ajp.160.9.1696

Publication date: 01 September 2003

Pages1702–1705

OBJECTIVE: The World Trade Center disaster was of unprecedented magnitude and impact in U.S. history. The authors conducted a pilot survey investigating these effects. METHOD: A questionnaire regarding the disaster was sent to responders to an ...

https://doi.org/10.1176/appi.ajp.160.9.1702

Publication date: 01 September 2003

Pages1705–1707

OBJECTIVE: Disturbed regulation of both the hypothalamic-pituitary-adrenal (HPA) axis and the sympathoadrenomedullary system in posttraumatic stress disorder (PTSD) suggests that immune function, which is modulated by these systems, also may be ...

https://doi.org/10.1176/appi.ajp.160.9.1705

Letter to the Editor

Book Forum: Mind and Brain

Book Forum: Gender Issues

Book Forum: International Views

Book Forum: Neuropsychiatry

Correction

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