American Journal of Psychiatry
- Volume 160
- Number 9
- September 2003
In This Issue
Editorial
Reviews and Overviews
Publication date: 01 September 2003
Pages1554–1565OBJECTIVE: Previous theories have emphasized the role of excessive glucocorticoid activity in the pathology of chronic stress. Nevertheless, insufficient glucocorticoid signaling (resulting from decreased hormone bioavailability or reduced hormone ...
https://doi.org/10.1176/appi.ajp.160.9.1554Publication date: 01 September 2003
Pages1566–1577OBJECTIVE: When there exists no single source of information (informant) to validly measure a characteristic, it is typically recommended that data from multiple informants be used. In psychiatric assessment and research, however, multiple informants ...
https://doi.org/10.1176/appi.ajp.160.9.1566Images in Neuroscience
Images in Psychiatry
Article
Publication date: 01 September 2003
Pages1580–1586OBJECTIVE: This study investigated the schizophrenia phenotype in 24 subjects with 22q11 deletion syndrome (22qDS) and schizophrenia (22qDS-schizophrenia), a rare but relatively homogenous genetic subtype of schizophrenia associated with a microdeletion ...
https://doi.org/10.1176/appi.ajp.160.9.1580Publication date: 01 September 2003
Pages1587–1594OBJECTIVE: Identification of the genetically related disorders in the putative schizophrenia spectrum is an unresolved problem. Data from the Finnish Adoptive Family Study of Schizophrenia, which was designed to disentangle genetic and environmental ...
https://doi.org/10.1176/appi.ajp.160.9.1587Publication date: 01 September 2003
Pages1595–1605OBJECTIVE: Sensory gating assessed via EEG in a paired-click paradigm has often served as a neurophysiological metric of attentional function in schizophrenia. However, the standard EEG measure of sensory gating using the P50 component at electrode Cz ...
https://doi.org/10.1176/appi.ajp.160.9.1595Publication date: 01 September 2003
Pages1606–1613OBJECTIVE: Although well documented, regional brain structural abnormalities in schizophrenia are nonspecific, and morphometric parameters show significant overlapping between patients and healthy comparison subjects. An increasing number of studies have ...
https://doi.org/10.1176/appi.ajp.160.9.1606Publication date: 01 September 2003
Pages1614–1617OBJECTIVE: The authors previously reported that men with chronic schizophrenia had a smaller vermian subregion than did healthy men. In this study, they tested whether posterior superior vermis reduction would be seen in a larger group of schizophrenia ...
https://doi.org/10.1176/appi.ajp.160.9.1614Publication date: 01 September 2003
Pages1618–1620OBJECTIVE: This study was designed to prospectively examine differential effects of sustained “high” and “low” serum prolactin levels on bone mineral density and peripheral markers of bone metabolism. METHOD: A dual-energy X-ray absorptiometer was used to ...
https://doi.org/10.1176/appi.ajp.160.9.1618Publication date: 01 September 2003
Pages1621–1626OBJECTIVE: Attentional deficits have been identified as an abnormality that individuals with schizotypal personality disorder share with schizophrenia patients. The purpose of this study was to examine automatic sensorimotor gating and controlled ...
https://doi.org/10.1176/appi.ajp.160.9.1621Publication date: 01 September 2003
Pages1627–1635OBJECTIVE: Methods to prevent two major mental disorders, schizophrenia and conduct disorder, have been elusive. This study assessed the effects of an early nutritional, educational, and physical exercise enrichment program on adult outcome for ...
https://doi.org/10.1176/appi.ajp.160.9.1627Publication date: 01 September 2003
Pages1636–1642OBJECTIVE: Utilizing data from a previously characterized registry of subjects with bipolar illness, the authors examined age at onset of the first illness episode in cohorts of subjects born from 1900 through 1939 and from 1940 through 1959. METHOD: ...
https://doi.org/10.1176/appi.ajp.160.9.1636Publication date: 01 September 2003
Pages1643–1650OBJECTIVE: Gender differences in antidepressant treatment response, side effects, dropout rates, and plasma concentrations were examined in patients with major and predominantly melancholic depression. METHOD: The study included a subgroup of 292 ...
https://doi.org/10.1176/appi.ajp.160.9.1643Publication date: 01 September 2003
Pages1651–1658OBJECTIVE: The authors compared the efficacy and safety of aripiprazole, a novel antipsychotic, to placebo for treatment of patients in an acute manic or mixed episode of bipolar disorder. METHOD: This 3-week, multicenter, double-blind study randomly ...
https://doi.org/10.1176/appi.ajp.160.9.1651Publication date: 01 September 2003
Pages1659–1662OBJECTIVE: This study examined the association of depression severity and drug injection HIV risk behavior among injection drug users. METHOD: Injection drug users who met the DSM-IV criteria for major depressive disorder, dysthymia, or substance-induced ...
https://doi.org/10.1176/appi.ajp.160.9.1659Publication date: 01 September 2003
Pages1663–1669OBJECTIVE: Building on findings about the prevalence and incidence of depression over a 40-year period, the authors provide data on trends in cigarette smoking and associations with depression. METHOD: Data come from interviews with adult population ...
https://doi.org/10.1176/appi.ajp.160.9.1663Publication date: 01 September 2003
Pages1670–1676OBJECTIVE: Epidemiological studies have reported an association between smoking and mental disorders. However, little is known about the impairment associated with nicotine dependence. METHOD: The authors assessed health-related quality of life, ...
https://doi.org/10.1176/appi.ajp.160.9.1670Publication date: 01 September 2003
Pages1677–1683OBJECTIVE: The feasibility of the 1999 voluntary, community-based National Alcohol Screening Day (NASD) was assessed by determining 1) the extent to which community and college sites were registered to hold screenings and the extent to which the subjects ...
https://doi.org/10.1176/appi.ajp.160.9.1677Publication date: 01 September 2003
Pages1684–1690OBJECTIVE: Community surveys have demonstrated significant psychological distress since the terrorist attacks of Sept. 11, 2001. Since people with posttraumatic stress disorder (PTSD) and other mental illnesses are especially vulnerable to stressful ...
https://doi.org/10.1176/appi.ajp.160.9.1684Brief Report
Publication date: 01 September 2003
Pages1691–1693OBJECTIVE: Leukocyte counts and plasma neopterin levels were determined in autistic children and matched healthy comparison subjects. METHOD: Blood from 31 autistic children and 28 age- and gender-matched healthy comparison subjects was analyzed for ...
https://doi.org/10.1176/appi.ajp.160.9.1691Publication date: 01 September 2003
Pages1693–1696OBJECTIVE: To examine brain-behavior relationships in attention deficit hyperactivity disorder (ADHD), the authors obtained magnetic resonance imaging (MRI) scans of monozygotic twins discordant for ADHD. METHOD: National recruitment was followed by in-...
https://doi.org/10.1176/appi.ajp.160.9.1693Publication date: 01 September 2003
Pages1696–1698OBJECTIVE: Comorbid bipolar and panic disorders aggregate in families. A phenotypic trait shared by both disorders is the sudden shift in affect observed in panic attacks and some rapid cycling states. The authors investigated whether comorbidity of ...
https://doi.org/10.1176/appi.ajp.160.9.1696Publication date: 01 September 2003
Pages1699–1701OBJECTIVE: The authors examined dopamine transporter density in the orbitofrontal cortex, dorsolateral prefrontal cortex, and amygdala in methamphetamine users and assessed the relationship of these measures to the subjects’ clinical characteristics. ...
https://doi.org/10.1176/appi.ajp.160.9.1699Publication date: 01 September 2003
Pages1702–1705OBJECTIVE: The World Trade Center disaster was of unprecedented magnitude and impact in U.S. history. The authors conducted a pilot survey investigating these effects. METHOD: A questionnaire regarding the disaster was sent to responders to an ...
https://doi.org/10.1176/appi.ajp.160.9.1702Publication date: 01 September 2003
Pages1705–1707OBJECTIVE: Disturbed regulation of both the hypothalamic-pituitary-adrenal (HPA) axis and the sympathoadrenomedullary system in posttraumatic stress disorder (PTSD) suggests that immune function, which is modulated by these systems, also may be ...
https://doi.org/10.1176/appi.ajp.160.9.1705Letter to the Editor
Book Forum: Mind and Brain
Book Forum: Gender Issues
Book Forum: International Views
Book Forum: Neuropsychiatry
Correction
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