American Journal of Psychiatry
- Volume 162
- Number 5
- May 2005
In This Issue
Editorial
Reviews and Overviews
Publication date: 01 May 2005
Pages836–846OBJECTIVE: Clinical trials in psychiatry frequently fail to maximize clinical utility for practicing clinicians, or, stated differently, available evidence is not perceived by clinicians (and other decision makers) as sufficiently relevant to clinical ...
https://doi.org/10.1176/appi.ajp.162.5.836Publication date: 01 May 2005
Pages847–855OBJECTIVE: DSM-III introduced somatoform disorders as a speculative diagnostic category for somatic symptoms “not explained by a general medical condition.” Although retained and enlarged in DSM-IV, somatoform disorders have been the subject of continuing ...
https://doi.org/10.1176/appi.ajp.162.5.847Images in Neuroscience
Introspections
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 May 2005
Pages867–875OBJECTIVE: Most studies of borderline personality disorder have drawn patients from among hospital inpatients or outpatients. The aims of this study were to examine the nature of borderline personality disorder patients in everyday clinical practice and ...
https://doi.org/10.1176/appi.ajp.162.5.867Publication date: 01 May 2005
Pages876–882OBJECTIVE: Relative to other mental disorders, the prevalence of obsessive-compulsive disorder (OCD) in the general population is not well established. Some epidemiological surveys have determined the prevalence of DSM-III OCD, but this is one of the ...
https://doi.org/10.1176/appi.ajp.162.5.876Publication date: 01 May 2005
Pages883–889OBJECTIVE: This study tracked the individual criteria of four DSM-IV personality disorders—borderline, schizotypal, avoidant, and obsessive-compulsive personality disorders—and how they change over 2 years. METHOD: This clinical sample of patients with ...
https://doi.org/10.1176/appi.ajp.162.5.883Publication date: 01 May 2005
Pages890–898OBJECTIVE: This study provides initial data on the reliability and factor structure of a measure of countertransference processes in clinical practice and examines the relation between these processes and patients’ personality pathology. METHOD: A ...
https://doi.org/10.1176/appi.ajp.162.5.890Publication date: 01 May 2005
Pages899–905OBJECTIVE: The goals of this study were to determine 1) the occurrence of various dissociative phenomena in patients with somatization disorder, 2) the occurrence of six different types of childhood interpersonal trauma in these patients, and 3) the ...
https://doi.org/10.1176/appi.ajp.162.5.899Publication date: 01 May 2005
Pages906–913OBJECTIVE: This study was designed to investigate the link among attention deficit hyperactivity disorder (ADHD) in adults, novelty-seeking temperament, and the 48-base pair (bp) dopamine D4 receptor (DRD4) gene variant. METHOD: This study drew from a ...
https://doi.org/10.1176/appi.ajp.162.5.906Publication date: 01 May 2005
Pages915–923OBJECTIVE: The serotonin system is believed to play a role in modulating impulsivity and violence. Previous imaging studies have implicated the anterior cingulate and orbitofrontal cortex in impulsive aggression. This study evaluated regional serotonin ...
https://doi.org/10.1176/appi.ajp.162.5.915Publication date: 01 May 2005
Pages924–930OBJECTIVE: In an ongoing molecular genetic study of temperament, participants were genotyped to examine the association of smoking with two polymorphisms of the serotonin transporter gene (SERT): the promoter region, 5-HTTLPR, and an intronic variable-...
https://doi.org/10.1176/appi.ajp.162.5.924Publication date: 01 May 2005
Pages931–938OBJECTIVE: Because neuroleptic treatment may cause long-lasting changes in brain structure and function, a group of patients with schizophrenia who had never been medicated was recruited to examine regional glucose metabolic rates in the frontal-striato-...
https://doi.org/10.1176/appi.ajp.162.5.931Publication date: 01 May 2005
Pages939–946OBJECTIVE: It is widely held that there is a delayed onset of antipsychotic action and that any early effects represent nonspecific behavioral effects. Recent research has shown that antipsychotic action begins within the first week. The authors tested ...
https://doi.org/10.1176/appi.ajp.162.5.939Publication date: 01 May 2005
Pages947–953OBJECTIVE: The first episode of psychotic illness is a key intervention point. The initial experience with medication can affect willingness to accept treatment. Further, relapse prevention is a treatment cornerstone during the first years of illness ...
https://doi.org/10.1176/appi.ajp.162.5.947Publication date: 01 May 2005
Pages954–962OBJECTIVE: Weight gain is commonly observed with olanzapine treatment and can increase the risk for obesity, cardiovascular disease, hypertension, and diabetes mellitus. This study examined the effectiveness of sibutramine, an approved weight loss agent, ...
https://doi.org/10.1176/appi.ajp.162.5.954Publication date: 01 May 2005
Pages963–969OBJECTIVE: The present study examined prospectively the relationship between memory of the traumatic event and subsequent development of posttraumatic stress disorder (PTSD). More specifically, the aims of this study were to 1) investigate the possibility ...
https://doi.org/10.1176/appi.ajp.162.5.963Publication date: 01 May 2005
Pages970–976OBJECTIVE: Posttraumatic stress disorder (PTSD) is often comorbid with other psychiatric disorders but often goes unrecognized. The effects of PTSD comorbidity are unclear, especially in patients with severe mental illness. The authors assessed short-term ...
https://doi.org/10.1176/appi.ajp.162.5.970Publication date: 01 May 2005
Pages977–982OBJECTIVE: This study assessed the incidence, severity, and course of expressed suicidal intent in depressed patients who were treated with ECT. The data are from the first phase of an ongoing, collaborative multicenter study, the overall aim of which was ...
https://doi.org/10.1176/appi.ajp.162.5.977Publication date: 01 May 2005
Pages983–991OBJECTIVE: Although there have been case reports suggesting a relationship between treatment with the acne medication isotretinoin and the development of depression and suicide, this topic remains controversial. In order for isotretinoin to cause ...
https://doi.org/10.1176/appi.ajp.162.5.983Brief Report
Publication date: 01 May 2005
Pages992–994OBJECTIVE: Results of basal peripheral cortisol measures in posttraumatic stress disorder (PTSD) have been variable. The authors’ goal was to measure CSF cortisol concentrations, which more accurately reflect brain glucocorticoid exposure, in subjects ...
https://doi.org/10.1176/appi.ajp.162.5.992Publication date: 01 May 2005
Pages995–997OBJECTIVE: To test the hypothesis that early life trauma results in adult stress hormone alterations in individuals with personality disorders, the authors examined the relationship between history of childhood adversity and lumbar CSF corticotropin-...
https://doi.org/10.1176/appi.ajp.162.5.995Publication date: 01 May 2005
Pages998–1000OBJECTIVE: The authors’ goal was to determine whether cortisol circadian rhythm alterations observed in younger subjects with posttraumatic stress disorder (PTSD) are also present in geriatric trauma survivors with PTSD. METHOD: Salivary cortisol levels ...
https://doi.org/10.1176/appi.ajp.162.5.998Publication date: 01 May 2005
Pages1000–1002OBJECTIVE: This pilot study investigated the mental health status of women after genital mutilation. Although experts have assumed that circumcised women are more prone to developing psychiatric illnesses than the general population, there has been little ...
https://doi.org/10.1176/appi.ajp.162.5.1000Publication date: 01 May 2005
Pages1003–1005OBJECTIVE: The authors examined the genetic polymorphisms of alcohol dehydrogenase 2 and 3 (ADH2 and ADH3) and aldehyde dehydrogenase (ALDH2) in patients diagnosed as having Cloninger’s type I or type II alcoholism. METHOD: Seventy-two alcoholic men and ...
https://doi.org/10.1176/appi.ajp.162.5.1003Publication date: 01 May 2005
Pages1005–1007OBJECTIVE: The authors evaluated the association of three functional promoter polymorphisms of the ADH4 gene with alcohol dependence. METHOD: DNA from 92 alcohol-dependent patients and 92 healthy comparison subjects was genotyped for all three ...
https://doi.org/10.1176/appi.ajp.162.5.1005Publication date: 01 May 2005
Pages1008–1010OBJECTIVE: This study clarified the early characteristics of substance use disorders in patients with first-episode bipolar I disorder. METHOD: The authors evaluated substance use disorders, associated factors, and clinical course, prospectively, in the ...
https://doi.org/10.1176/appi.ajp.162.5.1008Publication date: 01 May 2005
Pages1010–1012OBJECTIVE: The atypical antipsychotic risperidone significantly raises plasma prolactin levels in patients, but clozapine, olanzapine, and quetiapine do not. The differences in neuroendocrine response may be connected with the metabolism of the ...
https://doi.org/10.1176/appi.ajp.162.5.1010Publication date: 01 May 2005
Pages1013–1016OBJECTIVE: The purpose of this investigation was to evaluate the effects of clozapine and risperidone on spatial working memory in patients with schizophrenia. METHOD: Spatial working memory performance was evaluated at baseline and after 17 and 29 weeks ...
https://doi.org/10.1176/appi.ajp.162.5.1013Publication date: 01 May 2005
Pages1017–1019OBJECTIVE: This study compared suicidality in families of adult male suicide completers and community comparison subjects. METHOD: Two hundred forty-seven relatives of 25 male suicide completers and 171 relatives of 25 matched comparison subjects were ...
https://doi.org/10.1176/appi.ajp.162.5.1017Letter to the Editor
Book Forum: Geriatric Psychiatry
Book Forum: Posttraumatic Stress Disorder
Book Forum: Substance/Alcohol Abuse
Book Forum: Cultural Psychiatry
Correction
Past Issues
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