American Journal of Psychiatry

Objective: Cognitive remediation therapy for schizophrenia was developed to treat cognitive problems that affect functioning, but the treatment effects may depend on the type of trial methodology adopted. The present meta-analysis will determine the ...

https://doi.org/10.1176/appi.ajp.2010.10060855

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The Impact of National Health Care Reform on Adults With Severe Mental Disorders

Publication date: 01 May 2011

Pages486–494

Objective: Little is known about the effect recent health care reform legislation will have on coverage of individuals with severe mental disorders. The authors examined current and predicted sources of insurance coverage and use of mental health services ...

https://doi.org/10.1176/appi.ajp.2010.10060792

Clinical and Psychosocial Predictors of Suicide Attempts and Nonsuicidal Self-Injury in the Adolescent Depression Antidepressants and Psychotherapy Trial (ADAPT)

Publication date: 01 May 2011

Pages495–501

Objective: The authors assessed whether clinical and psychosocial factors in depressed adolescents at baseline predict suicide attempts and nonsuicidal self-injury over 28 weeks of follow-up. Method: Participants were 164 adolescents with major depressive ...

https://doi.org/10.1176/appi.ajp.2010.10050718

Deep Brain Stimulation for Treatment-Resistant Depression: Follow-Up After 3 to 6 Years

Publication date: 01 May 2011

Pages502–510

Objective: A prevalence of at least 30% for treatment-resistant depression has prompted the investigation of alternative treatment strategies. Deep brain stimulation (DBS) is a promising targeted approach involving the bilateral placement of electrodes at ...

https://doi.org/10.1176/appi.ajp.2010.10081187

Association of Cerebrovascular Events With Antidepressant Use: A Case-Crossover Study

Publication date: 01 May 2011

Pages511–521

Objective: The authors sought to assess the risk of cerebrovascular events associated with use of antidepressant medications. Method: The authors conducted a case-crossover study of 24,214 patients with stroke enrolled in the National Health Insurance ...

https://doi.org/10.1176/appi.ajp.2010.10071064

Association of Schizophrenia in 22q11.2 Deletion Syndrome and Gray Matter Volumetric Deficits in the Superior Temporal Gyrus

Publication date: 01 May 2011

Pages522–529

Objective: Individuals with 22q11.2 deletion syndrome are known to be at high risk of developing schizophrenia. Previous imaging studies have provided limited data on the relation of schizophrenia expression in 22q11.2 deletion syndrome to specific ...

https://doi.org/10.1176/appi.ajp.2010.10081230

Investigation of Cortical Thickness Abnormalities in Lithium-Free Adults With Bipolar I Disorder Using Cortical Pattern Matching

Publication date: 01 May 2011

Pages530–539

Objective: Although several lines of evidence implicate gray matter abnormalities in the prefrontal cortex and anterior cingulate cortex in patients with bipolar disorder, findings have been largely inconsistent across studies. Differences in patients' ...

https://doi.org/10.1176/appi.ajp.2010.10060896

Lower Ventral Striatal Activation During Reward Anticipation in Adolescent Smokers

Publication date: 01 May 2011

Pages540–549

Objective: Adolescents are particularly vulnerable to addiction, and in the case of smoking, this often leads to long-lasting nicotine dependence. The authors investigated a possible neural mechanism underlying this vulnerability. Method: Functional MRI was ...

https://doi.org/10.1176/appi.ajp.2010.10071024