American Journal of Psychiatry
- Volume 159
- Number 10
- October 2002
Editorial
Presidential Paper
Reviews and Overviews
Publication date: 01 October 2002
Pages1642–1652OBJECTIVE: Studies of the neurobiological processes underlying drug addiction primarily have focused on limbic subcortical structures. Here the authors evaluated the role of frontal cortical structures in drug addiction. METHOD: An integrated model of ...
https://doi.org/10.1176/appi.ajp.159.10.1642Publication date: 01 October 2002
Pages1653–1664OBJECTIVE: Although nonadherence with the antipsychotic medication regimen is a common barrier to the effective treatment for schizophrenia, knowledge is limited about how to improve medication adherence. This systematic literature review examined ...
https://doi.org/10.1176/appi.ajp.159.10.1653Introspections
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 October 2002
Pages1675–1681OBJECTIVE: Posttraumatic stress disorder (PTSD) develops in only a subset of persons exposed to traumatic stress, suggesting the existence of stressor and individual differences that influence risk. In this study the authors examined the heritability of ...
https://doi.org/10.1176/appi.ajp.159.10.1675Publication date: 01 October 2002
Pages1682–1688OBJECTIVE: The authors evaluated memory performance in Holocaust survivors and its association with posttraumatic stress disorder (PTSD) and age. METHOD: Memory performance was measured in Holocaust survivors with PTSD (N=31) and without PTSD (N=16) and ...
https://doi.org/10.1176/appi.ajp.159.10.1682Publication date: 01 October 2002
Pages1689–1695OBJECTIVE: The purpose of this study was to explore the relationship between combat-related posttraumatic stress disorder (PTSD) and specific augmentation versus reduction patterns for the N100 and P200 components of auditory event-related potentials ...
https://doi.org/10.1176/appi.ajp.159.10.1689Publication date: 01 October 2002
Pages1696–1701OBJECTIVE: The potential for chronicity and treatment resistance once posttraumatic stress disorder (PTSD) has become established has stimulated interest in understanding the early pathogenesis of the disorder. Arousal regulation and memory consolidation ...
https://doi.org/10.1176/appi.ajp.159.10.1696Publication date: 01 October 2002
Pages1702–1710OBJECTIVE: The study examined whether paroxetine inhibits the human norepinephrine transporter in addition to the human serotonin (5-HT) transporter in patients with major depressive disorder. METHOD: In an open-label, parallel-group, forced-titration ...
https://doi.org/10.1176/appi.ajp.159.10.1702Publication date: 01 October 2002
Pages1711–1717OBJECTIVE: This study explored whether “switching” (i.e., the direct transition from one mood polarity to the other) has significant prognostic implications in patients with bipolar disorder. METHOD: Bipolar disorder patients (N=97) whose first ...
https://doi.org/10.1176/appi.ajp.159.10.1711Publication date: 01 October 2002
Pages1718–1723OBJECTIVE: A previous study reported a higher than normal density of dopamine D2 receptors in psychotic mania but not in nonpsychotic mania. The purpose of this study was to further examine D2 receptor density in a larger sample of nonpsychotic manic ...
https://doi.org/10.1176/appi.ajp.159.10.1718Publication date: 01 October 2002
Pages1724–1730OBJECTIVE: The study assessed the contribution of depressive symptoms and cognitive impairment to the prediction of self-neglect in elderly persons living in the community. METHOD: Data were drawn from the New Haven Established Populations for ...
https://doi.org/10.1176/appi.ajp.159.10.1724Publication date: 01 October 2002
Pages1731–1737OBJECTIVE: Evidence that major depression can be a significant hindrance to smoking cessation prompted this examination of the usefulness of sertraline as a cessation aid for smokers with a history of major depression. Specifically, sertraline’s efficacy ...
https://doi.org/10.1176/appi.ajp.159.10.1731Publication date: 01 October 2002
Pages1738–1745OBJECTIVE: The authors compared treatment and outcomes for depressed primary care patients with and without comorbid medical conditions and assessed the impact of quality improvement programs for these patients. METHOD: The study group included 1,356 ...
https://doi.org/10.1176/appi.ajp.159.10.1738Publication date: 01 October 2002
Pages1746–1751OBJECTIVE: Suicide attempts predict repeat attempts and suicide completion. Major depression requiring hospitalization is a risk factor for suicidal acts, particularly in the 2 years following discharge. The authors prospectively studied the adequacy of ...
https://doi.org/10.1176/appi.ajp.159.10.1746Publication date: 01 October 2002
Pages1752–1759OBJECTIVE: Clinical and epidemiology studies have implicated depression as a risk factor in the morbidity and mortality of many human diseases. This study sought to determine if depression was associated with alterations in cellular immunity variables—...
https://doi.org/10.1176/appi.ajp.159.10.1752Publication date: 01 October 2002
Pages1760–1766OBJECTIVE: The well-documented association between maladaptive personality traits and substance use disorders has given rise to diverse explanatory models. In this investigation the authors examined one such explanation, that certain personality traits ...
https://doi.org/10.1176/appi.ajp.159.10.1760Publication date: 01 October 2002
Pages1767–1774OBJECTIVE: This study examined whether early or late processes in semantic networks were abnormal in women with a diagnosis of schizotypal personality disorder. The N400 component of the EEG event-related potentials was used as a probe of semantic ...
https://doi.org/10.1176/appi.ajp.159.10.1767Brief Report
Publication date: 01 October 2002
Pages1775–1777OBJECTIVE: A family history approach was used to determine if posttraumatic stress disorder (PTSD) with secondary psychotic symptoms was associated with a familial vulnerability to schizophrenia and other psychoses. METHOD: Family history methods were ...
https://doi.org/10.1176/appi.ajp.159.10.1775Publication date: 01 October 2002
Pages1777–1779OBJECTIVE: Posttraumatic stress disorder (PTSD), particularly in combat veterans with chronic illness, is often refractory to standard pharmacological interventions. There is a need to test adjunctive treatments to boost response. METHOD: Subjects were 19 ...
https://doi.org/10.1176/appi.ajp.159.10.1777Publication date: 01 October 2002
Pages1780–1782OBJECTIVE: This study examined implicit sequence learning in patients with obsessive-compulsive disorder (OCD) under dual-task conditions. Frontal-striatal networks support implicit learning and are implicated in the pathophysiology of OCD. Neuroimaging ...
https://doi.org/10.1176/appi.ajp.159.10.1780Publication date: 01 October 2002
Pages1783–1785OBJECTIVE: Serotonin abnormalities may be involved in the etiopathogenesis of obsessive-compulsive disorder (OCD). The silent G-to-C substitution at nucleotide 861 of the coding region of the 5-HT1Dβ receptor gene may be associated with liability to OCD. ...
https://doi.org/10.1176/appi.ajp.159.10.1783Publication date: 01 October 2002
Pages1785–1787OBJECTIVE: The authors examined the distribution of catechol O-methyltransferase (COMT) genotypes in patients with panic disorder as well as the relationship between a COMT polymorphism and the clinical characteristics of these patients. METHOD: Fifty-one ...
https://doi.org/10.1176/appi.ajp.159.10.1785Publication date: 01 October 2002
Pages1788–1790OBJECTIVE: The authors hypothesized that because patients with body dysmorphic disorder are preoccupied with their appearance and aesthetics, they are more likely to have an occupation or education in art and design than patients with other psychiatric ...
https://doi.org/10.1176/appi.ajp.159.10.1788Publication date: 01 October 2002
Pages1790–1792OBJECTIVE: Elevated plasma homocysteine has been found to be a risk factor for Alzheimer’s disease as well as cerebral vascular disease, suggesting that some risk factors can accelerate or increase the severity of several CNS disease processes. The ...
https://doi.org/10.1176/appi.ajp.159.10.1790Letter to the Editor
Book Forum: Consultation-Liaison Psychiatry
Book Forum: History of Psychiatry
Book Forum: Psychopathy and Violence
Book Forum: Law and Ethics
Book Forum: How the Mind Works
Book Forum: PTSD
Correction
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