American Journal of Psychiatry
- Volume 163
- Number 9
- September 2006
In This Issue
Editorial
Images in Neuroscience
Reviews and Overviews
Publication date: 01 September 2006
Pages1493–1501Objective: To improve interventions for depressed older adults, data are needed on the comparative effects of pharmacotherapy versus psychotherapy. Given that most older adults with clinically significant depressive symptoms do not have major ...
https://doi.org/10.1176/ajp.2006.163.9.1493Introspections
Treatment in Psychiatry
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 September 2006
Pages1519–1530Objective: More than 40% of patients with major depressive disorder do not achieve remission even after two optimally delivered trials of antidepressant medications. This study compared the effectiveness of lithium versus triiodothyronine (T ...
https://doi.org/10.1176/ajp.2006.163.9.1519Publication date: 01 September 2006
Pages1531–1541Objective: The purpose of this study was to compare the effectiveness and tolerability of tranylcypromine and combination treatment with extended-release venlafaxine and mirtazapine in patients with treatment-resistant major depression whose ...
https://doi.org/10.1176/ajp.2006.163.9.1531Publication date: 01 September 2006
Pages1542–1548Objective: Loss of response to a previously effective antidepressant is a common clinical problem. Retrospective analyses have shown that the pattern of response during antidepressant treatment (late onset and persistent versus other patterns) ...
https://doi.org/10.1176/ajp.2006.163.9.1542Publication date: 01 September 2006
Pages1549–1553Objective: The authors previously reported strong evidence for familial aggregation of postpartum (puerperal) psychotic episodes in women with bipolar disorder. The authors here examine whether vulnerability to postpartum triggering of ...
https://doi.org/10.1176/ajp.2006.163.9.1549Publication date: 01 September 2006
Pages1554–1560Objective: The authors used a large sample collected for genetic studies to determine whether a chronic course of illness defines a familial clinical subtype in major depressive disorder. Method: A measure of lifetime ...
https://doi.org/10.1176/ajp.2006.163.9.1554Publication date: 01 September 2006
Pages1561–1568Objective: Research on the workplace costs of mood disorders has focused largely on major depressive episodes. Bipolar disorder has been overlooked both because of the failure to distinguish between major depressive disorder and bipolar ...
https://doi.org/10.1176/ajp.2006.163.9.1561Publication date: 01 September 2006
Pages1569–1576Objective: This study assessed the relationship between depression severity and job performance among employed primary care patients. Method: In a 2001–2004 longitudinal observational study of depression’s affect on work ...
https://doi.org/10.1176/ajp.2006.163.9.1569Publication date: 01 September 2006
Pages1577–1579BACKGROUND: In addition to symptoms, DSM-IV criteria for major depression require clinical significance, operationalized via reports of receipt of care or interference in functioning. The authors examined whether this confounding of symptoms ...
https://doi.org/10.1176/ajp.2006.163.9.1577Publication date: 01 September 2006
Pages1580–1587Objective: A previous positron emission tomography (PET) study reported increased serotonin 5-HT 2A receptor binding in unmedicated depressed patients with high scores on the Dysfunctional Attitudes Scale. The purpose of the ...
https://doi.org/10.1176/ajp.2006.163.9.1580Publication date: 01 September 2006
Pages1588–1593Objective: The lower expressing allele of the serotonin transporter gene 5′ promoter region (5-HTTLPR) polymorphism is reported to be associated with susceptibility to depression and suicidality in response to stressful life events. The authors ...
https://doi.org/10.1176/ajp.2006.163.9.1588Publication date: 01 September 2006
Pages1594–1602Objective: Several antidepressants raise striatal dopamine, but the role of striatal dopamine during major depressive episodes is unclear. Striatal [ 11 C]raclopride binding potential measured with positron emission ...
https://doi.org/10.1176/ajp.2006.163.9.1594Publication date: 01 September 2006
Pages1603–1610Objective: Altered patterns of brain activity during cognitive tasks have been demonstrated using functional magnetic resonance imaging (fMRI) in mild cognitive impairment and Alzheimer’s disease. However, there have been few studies of adults ...
https://doi.org/10.1176/ajp.2006.163.9.1603Publication date: 01 September 2006
Pages1611–1621Objective: This study attempted to compare two models for selective (people at elevated risk) and indicated (those with subsyndromal depressive symptoms) prevention and to determine the optimal strategy for prevention of late-life depression. ...
https://doi.org/10.1176/ajp.2006.163.9.1611Publication date: 01 September 2006
Pages1622–1629Objective: Autism is a complex, largely genetic psychiatric disorder. In the majority of cases, the cause of autism is not known, but there is strong evidence for a genetic etiology. To identify candidate genes, the physical mapping of balanced ...
https://doi.org/10.1176/ajp.2006.163.9.1622Brief Report
Publication date: 01 September 2006
Pages1630–1633Objective: The authors sought to determine innate immune system activation following psychosocial stress in patients with major depression and increased early life stress. Method: Plasma interleukin (IL)-6, lymphocyte ...
https://doi.org/10.1176/ajp.2006.163.9.1630Publication date: 01 September 2006
Pages1633–1636Objective: This study examines the relationship between age at onset of bipolar I disorder and illness characteristics among adults in a community sample. Method: The National Epidemiologic Survey on Alcohol and Related ...
https://doi.org/10.1176/ajp.2006.163.9.1633Publication date: 01 September 2006
Pages1636–1638Objective: In the study of bipolar affective disorder and schizophrenia, there is some evidence suggesting a phenotypic and genetic overlap between the two disorders. A possible link between bipolar affective disorder and schizophrenia remains ...
https://doi.org/10.1176/ajp.2006.163.9.1636Publication date: 01 September 2006
Pages1639–1641Objective: The authors examined gender differences in d -amphetamine-induced displacements of [ 18 F]fallypride in the striatal and extrastriatal brain regions and the correlations of these displacements ...
https://doi.org/10.1176/ajp.2006.163.9.1639Letters to the Editor
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