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American Journal of Psychiatry

  • Volume 163
  • Number 9
  • September 2006

In This Issue

Editorial

Images in Neuroscience

Reviews and Overviews

Publication date: 01 September 2006

Pages1493–1501

Objective: To improve interventions for depressed older adults, data are needed on the comparative effects of pharmacotherapy versus psychotherapy. Given that most older adults with clinically significant depressive symptoms do not have major ...

https://doi.org/10.1176/ajp.2006.163.9.1493

Introspections

Treatment in Psychiatry

Clinical Case Conference

Images in Psychiatry

Article

Publication date: 01 September 2006

Pages1519–1530

Objective: More than 40% of patients with major depressive disorder do not achieve remission even after two optimally delivered trials of antidepressant medications. This study compared the effectiveness of lithium versus triiodothyronine (T ...

https://doi.org/10.1176/ajp.2006.163.9.1519

Publication date: 01 September 2006

Pages1542–1548

Objective: Loss of response to a previously effective antidepressant is a common clinical problem. Retrospective analyses have shown that the pattern of response during antidepressant treatment (late onset and persistent versus other patterns) ...

https://doi.org/10.1176/ajp.2006.163.9.1542

Publication date: 01 September 2006

Pages1549–1553

Objective: The authors previously reported strong evidence for familial aggregation of postpartum (puerperal) psychotic episodes in women with bipolar disorder. The authors here examine whether vulnerability to postpartum triggering of ...

https://doi.org/10.1176/ajp.2006.163.9.1549

Publication date: 01 September 2006

Pages1554–1560

Objective: The authors used a large sample collected for genetic studies to determine whether a chronic course of illness defines a familial clinical subtype in major depressive disorder. Method: A measure of lifetime ...

https://doi.org/10.1176/ajp.2006.163.9.1554

Publication date: 01 September 2006

Pages1561–1568

Objective: Research on the workplace costs of mood disorders has focused largely on major depressive episodes. Bipolar disorder has been overlooked both because of the failure to distinguish between major depressive disorder and bipolar ...

https://doi.org/10.1176/ajp.2006.163.9.1561

Publication date: 01 September 2006

Pages1569–1576

Objective: This study assessed the relationship between depression severity and job performance among employed primary care patients. Method: In a 2001–2004 longitudinal observational study of depression’s affect on work ...

https://doi.org/10.1176/ajp.2006.163.9.1569

Publication date: 01 September 2006

Pages1577–1579

BACKGROUND: In addition to symptoms, DSM-IV criteria for major depression require clinical significance, operationalized via reports of receipt of care or interference in functioning. The authors examined whether this confounding of symptoms ...

https://doi.org/10.1176/ajp.2006.163.9.1577

Publication date: 01 September 2006

Pages1580–1587

Objective: A previous positron emission tomography (PET) study reported increased serotonin 5-HT 2A receptor binding in unmedicated depressed patients with high scores on the Dysfunctional Attitudes Scale. The purpose of the ...

https://doi.org/10.1176/ajp.2006.163.9.1580

Publication date: 01 September 2006

Pages1588–1593

Objective: The lower expressing allele of the serotonin transporter gene 5′ promoter region (5-HTTLPR) polymorphism is reported to be associated with susceptibility to depression and suicidality in response to stressful life events. The authors ...

https://doi.org/10.1176/ajp.2006.163.9.1588

Publication date: 01 September 2006

Pages1594–1602

Objective: Several antidepressants raise striatal dopamine, but the role of striatal dopamine during major depressive episodes is unclear. Striatal [ 11 C]raclopride binding potential measured with positron emission ...

https://doi.org/10.1176/ajp.2006.163.9.1594

Publication date: 01 September 2006

Pages1603–1610

Objective: Altered patterns of brain activity during cognitive tasks have been demonstrated using functional magnetic resonance imaging (fMRI) in mild cognitive impairment and Alzheimer’s disease. However, there have been few studies of adults ...

https://doi.org/10.1176/ajp.2006.163.9.1603

Publication date: 01 September 2006

Pages1611–1621

Objective: This study attempted to compare two models for selective (people at elevated risk) and indicated (those with subsyndromal depressive symptoms) prevention and to determine the optimal strategy for prevention of late-life depression. ...

https://doi.org/10.1176/ajp.2006.163.9.1611

Brief Report

Publication date: 01 September 2006

Pages1630–1633

Objective: The authors sought to determine innate immune system activation following psychosocial stress in patients with major depression and increased early life stress. Method: Plasma interleukin (IL)-6, lymphocyte ...

https://doi.org/10.1176/ajp.2006.163.9.1630

Publication date: 01 September 2006

Pages1633–1636

Objective: This study examines the relationship between age at onset of bipolar I disorder and illness characteristics among adults in a community sample. Method: The National Epidemiologic Survey on Alcohol and Related ...

https://doi.org/10.1176/ajp.2006.163.9.1633

Publication date: 01 September 2006

Pages1636–1638

Objective: In the study of bipolar affective disorder and schizophrenia, there is some evidence suggesting a phenotypic and genetic overlap between the two disorders. A possible link between bipolar affective disorder and schizophrenia remains ...

https://doi.org/10.1176/ajp.2006.163.9.1636

Publication date: 01 September 2006

Pages1639–1641

Objective: The authors examined gender differences in d -amphetamine-induced displacements of [ 18 F]fallypride in the striatal and extrastriatal brain regions and the correlations of these displacements ...

https://doi.org/10.1176/ajp.2006.163.9.1639

Letters to the Editor

Corrections

Book Forum

Books Received

Official Actions

Past Issues

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