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American Journal of Psychiatry

  • Volume 156
  • Number 4
  • April 1999

Editorial

Images in Neuroscience

Special Article

Publication date: 01 April 1999

Pages505–524

The American Journal of Psychiatry has received a number of letters in response to my earlier “Framework” article (1). Some of these are reprinted elsewhere in this issue, and I have answered them briefly there. However, one issue raised by some letters ...

https://doi.org/10.1176/ajp.156.4.505

Regular Article

Publication date: 01 April 1999

Pages525–530

OBJECTIVE: An association between childhood behavioral disturbance and adulthood schizophrenia has been seen previously in retrospective or follow-back studies and in prospective studies. The authors examined the relationship between childhood behavioral ...

https://doi.org/10.1176/ajp.156.4.525

Publication date: 01 April 1999

Pages531–537

OBJECTIVE: Results of previous studies suggest that memory complaints may predict cognitive decline and dementia among elderly people in whom cognitive impairment is already apparent. However, cognitive decline is often a gradual process, and elderly ...

https://doi.org/10.1176/ajp.156.4.531

Publication date: 01 April 1999

Pages538–543

OBJECTIVE: The purpose of this study was to examine psychological and behavioral functioning in psychiatrically hospitalized adolescents who report histories of childhood abuse. METHOD: Three hundred twenty-two subjects completed an assessment battery of ...

https://doi.org/10.1176/ajp.156.4.538

Publication date: 01 April 1999

Pages544–549

OBJECTIVE: This study examined the treatment response of patients with first-episode schizophrenia and schizoaffective disorder and potential predictors of response. METHOD: First-episode patients were assessed on measures of psychopathology, cognition, ...

https://doi.org/10.1176/ajp.156.4.544

Publication date: 01 April 1999

Pages550–556

OBJECTIVE: Few studies have examined the course of coexisting dementia and depression. The purpose of this study was to compare elderly patients who had coexisting dementia and depression with elderly patients who had either disorder alone in terms of ...

https://doi.org/10.1176/ajp.156.4.550

Publication date: 01 April 1999

Pages557–563

OBJECTIVE: Several studies have shown familial aggregation of some axis I psychiatric disorders in families ascertained through a single autistic proband. In this study the authors examined the rate of axis I psychiatric disorders in nonautistic relatives ...

https://doi.org/10.1176/ajp.156.4.557

Publication date: 01 April 1999

Pages564–568

OBJECTIVE: This study sought to determine whether volumes of the hippocampus and amygdala are disproportionately smaller in subjects with Down’s syndrome than in normal comparison subjects and whether volume reduction is greater in Down’s syndrome ...

https://doi.org/10.1176/ajp.156.4.564

Publication date: 01 April 1999

Pages569–574

OBJECTIVE: The purpose of this study was to compare syndromes of parent-reported problems for children in 12 cultures. METHOD: Child Behavior Checklists were analyzed for 13,697 children and adolescents, ages 6 through 17 years, from general population ...

https://doi.org/10.1176/ajp.156.4.569

Publication date: 01 April 1999

Pages575–584

OBJECTIVE: The purpose of this study was to determine whether anterior limbic and para­limbic regions of the brain are differentially activated during the recollection and imagery of traumatic events in trauma-exposed individuals with and without ...

https://doi.org/10.1176/ajp.156.4.575

Publication date: 01 April 1999

Pages585–588

OBJECTIVE: The authors sought to carefully test, by using a technique of continuous CSF sampling, the hypothesis that basal elevations in CSF corticotropin-releasing hormone (CRH) concentrations exist in patients with posttraumatic stress disorder (PTSD). ...

https://doi.org/10.1176/ajp.156.4.585

Publication date: 01 April 1999

Pages589–595

OBJECTIVE: This study reports the rates of acute and chronic posttraumatic stress disorder (PTSD) in a suburban community study group of 122 victims of serious motor vehicle accidents and a comparison group of 42 (who had been involved in minor, non-motor-...

https://doi.org/10.1176/ajp.156.4.589

Publication date: 01 April 1999

Pages596–602

OBJECTIVE: Information processing, inhibitory, and gating deficits in human and animal model studies of schizophrenia are demonstrated by using prepulse inhibition of the startle reflex. Prepulse inhibition deficits in schizophrenic patients correlate ...

https://doi.org/10.1176/ajp.156.4.596

Publication date: 01 April 1999

Pages603–609

OBJECTIVE: The temporal lobe and associated structures have been previously implicated in the neuroanatomy of schizophrenia. This study was designed to assess the potential influence of gender on the morphology of temporal lobe structures, including the ...

https://doi.org/10.1176/ajp.156.4.603

Publication date: 01 April 1999

Pages610–616

OBJECTIVE: The goal of this placebo-controlled study was to evaluate the efficacy and safety of low doses of amisulpride, an atypical antipsychotic of the benzamide class with high affinity for D2 and D3 dopamine receptors, in the treatment of ...

https://doi.org/10.1176/ajp.156.4.610

Publication date: 01 April 1999

Pages617–623

OBJECTIVE: A relationship between schizotypal personality disorder and schizophrenia has been documented in behavioral genetic studies, and there are similarities in the cognitive deficits and brain abnormalities associated with these disorders. ...

https://doi.org/10.1176/ajp.156.4.617

Clinical Case Conference

Images in Psychiatry

Brief Report

Publication date: 01 April 1999

Pages631–633

OBJECTIVE: The aim of this study was to evaluate the frequency and course of sexual disturbances associated with clozapine and haloperidol and their potential influence on compliance with medication regimens in patients with schizophrenia. METHOD: The ...

https://doi.org/10.1176/ajp.156.4.631

Publication date: 01 April 1999

Pages634–636

OBJECTIVE: The authors estimated the expression of adhesion molecule receptors (VLA-4 and LFA-1) on T helper (CD4+) and T suppressor/cytotoxic (CD8+) lymphocytes in schizophrenic patients before and during antipsychotic treatment and studied the ...

https://doi.org/10.1176/ajp.156.4.634

Publication date: 01 April 1999

Pages637–639

OBJECTIVE: Primary, enduring negative symptoms have been distinguished from negative symptoms more generally and are used to define the deficit syndrome of schizophrenia. Although the validity of the deficit syndrome has been demonstrated by using brain ...

https://doi.org/10.1176/ajp.156.4.637

Publication date: 01 April 1999

Pages640–642

OBJECTIVE: Diabetes mellitus has been implicated as a risk factor for tardive dyskinesia. The authors examined the association between abnormal movements and impaired glucose metabolism, which often precedes the development of overt diabetes, in patients ...

https://doi.org/10.1176/ajp.156.4.640

Publication date: 01 April 1999

Pages643–645

OBJECTIVE: The authors’ goal was to determine whether improved outcomes from enhanced acute-phase (3-month) treatment for depression in primary care persisted. METHOD: They conducted a 19-month follow-up assessment of 156 patients with major depression in ...

https://doi.org/10.1176/ajp.156.4.643

Publication date: 01 April 1999

Pages646–649

OBJECTIVE: This study was designed to assess possible antidepressant effects of dehydroepiandrosterone (DHEA), an abundant adrenocortical hormone in humans. METHOD: Twenty-two patients with major depression, either medication-free or on stabilized ...

https://doi.org/10.1176/ajp.156.4.646

Publication date: 01 April 1999

Pages650–652

OBJECTIVE: The authors’ goal was to determine whether early termination of breast-feeding contributes to later alcohol dependence, as proposed more than 200 years ago by the British physician Thomas Trotter. METHOD: In 1959–1961, a multiple-specialty ...

https://doi.org/10.1176/ajp.156.4.650

Book Forum: Suicide

Book Forum: The End of Life

Book Forum: Sexuality

Book Forum: Child and Adolescent Psychiatry

Book Forum: Mental, Addictive, and Mood Disorders

Letter to the Editor

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