American Journal of Psychiatry
- Volume 156
- Number 4
- April 1999
Editorial
Images in Neuroscience
Special Article
Publication date: 01 April 1999
Pages505–524The American Journal of Psychiatry has received a number of letters in response to my earlier “Framework” article (1). Some of these are reprinted elsewhere in this issue, and I have answered them briefly there. However, one issue raised by some letters ...
https://doi.org/10.1176/ajp.156.4.505Regular Article
Publication date: 01 April 1999
Pages525–530OBJECTIVE: An association between childhood behavioral disturbance and adulthood schizophrenia has been seen previously in retrospective or follow-back studies and in prospective studies. The authors examined the relationship between childhood behavioral ...
https://doi.org/10.1176/ajp.156.4.525Publication date: 01 April 1999
Pages531–537OBJECTIVE: Results of previous studies suggest that memory complaints may predict cognitive decline and dementia among elderly people in whom cognitive impairment is already apparent. However, cognitive decline is often a gradual process, and elderly ...
https://doi.org/10.1176/ajp.156.4.531Publication date: 01 April 1999
Pages538–543OBJECTIVE: The purpose of this study was to examine psychological and behavioral functioning in psychiatrically hospitalized adolescents who report histories of childhood abuse. METHOD: Three hundred twenty-two subjects completed an assessment battery of ...
https://doi.org/10.1176/ajp.156.4.538Publication date: 01 April 1999
Pages544–549OBJECTIVE: This study examined the treatment response of patients with first-episode schizophrenia and schizoaffective disorder and potential predictors of response. METHOD: First-episode patients were assessed on measures of psychopathology, cognition, ...
https://doi.org/10.1176/ajp.156.4.544Publication date: 01 April 1999
Pages550–556OBJECTIVE: Few studies have examined the course of coexisting dementia and depression. The purpose of this study was to compare elderly patients who had coexisting dementia and depression with elderly patients who had either disorder alone in terms of ...
https://doi.org/10.1176/ajp.156.4.550Publication date: 01 April 1999
Pages557–563OBJECTIVE: Several studies have shown familial aggregation of some axis I psychiatric disorders in families ascertained through a single autistic proband. In this study the authors examined the rate of axis I psychiatric disorders in nonautistic relatives ...
https://doi.org/10.1176/ajp.156.4.557MRI Volumes of the Hippocampus and Amygdala in Adults With Down’s Syndrome With and Without Dementia
Publication date: 01 April 1999
Pages564–568OBJECTIVE: This study sought to determine whether volumes of the hippocampus and amygdala are disproportionately smaller in subjects with Down’s syndrome than in normal comparison subjects and whether volume reduction is greater in Down’s syndrome ...
https://doi.org/10.1176/ajp.156.4.564Publication date: 01 April 1999
Pages569–574OBJECTIVE: The purpose of this study was to compare syndromes of parent-reported problems for children in 12 cultures. METHOD: Child Behavior Checklists were analyzed for 13,697 children and adolescents, ages 6 through 17 years, from general population ...
https://doi.org/10.1176/ajp.156.4.569Publication date: 01 April 1999
Pages575–584OBJECTIVE: The purpose of this study was to determine whether anterior limbic and paralimbic regions of the brain are differentially activated during the recollection and imagery of traumatic events in trauma-exposed individuals with and without ...
https://doi.org/10.1176/ajp.156.4.575Publication date: 01 April 1999
Pages585–588OBJECTIVE: The authors sought to carefully test, by using a technique of continuous CSF sampling, the hypothesis that basal elevations in CSF corticotropin-releasing hormone (CRH) concentrations exist in patients with posttraumatic stress disorder (PTSD). ...
https://doi.org/10.1176/ajp.156.4.585Publication date: 01 April 1999
Pages589–595OBJECTIVE: This study reports the rates of acute and chronic posttraumatic stress disorder (PTSD) in a suburban community study group of 122 victims of serious motor vehicle accidents and a comparison group of 42 (who had been involved in minor, non-motor-...
https://doi.org/10.1176/ajp.156.4.589Publication date: 01 April 1999
Pages596–602OBJECTIVE: Information processing, inhibitory, and gating deficits in human and animal model studies of schizophrenia are demonstrated by using prepulse inhibition of the startle reflex. Prepulse inhibition deficits in schizophrenic patients correlate ...
https://doi.org/10.1176/ajp.156.4.596Publication date: 01 April 1999
Pages603–609OBJECTIVE: The temporal lobe and associated structures have been previously implicated in the neuroanatomy of schizophrenia. This study was designed to assess the potential influence of gender on the morphology of temporal lobe structures, including the ...
https://doi.org/10.1176/ajp.156.4.603Publication date: 01 April 1999
Pages610–616OBJECTIVE: The goal of this placebo-controlled study was to evaluate the efficacy and safety of low doses of amisulpride, an atypical antipsychotic of the benzamide class with high affinity for D2 and D3 dopamine receptors, in the treatment of ...
https://doi.org/10.1176/ajp.156.4.610Publication date: 01 April 1999
Pages617–623OBJECTIVE: A relationship between schizotypal personality disorder and schizophrenia has been documented in behavioral genetic studies, and there are similarities in the cognitive deficits and brain abnormalities associated with these disorders. ...
https://doi.org/10.1176/ajp.156.4.617Clinical Case Conference
Images in Psychiatry
Brief Report
Publication date: 01 April 1999
Pages631–633OBJECTIVE: The aim of this study was to evaluate the frequency and course of sexual disturbances associated with clozapine and haloperidol and their potential influence on compliance with medication regimens in patients with schizophrenia. METHOD: The ...
https://doi.org/10.1176/ajp.156.4.631Publication date: 01 April 1999
Pages634–636OBJECTIVE: The authors estimated the expression of adhesion molecule receptors (VLA-4 and LFA-1) on T helper (CD4+) and T suppressor/cytotoxic (CD8+) lymphocytes in schizophrenic patients before and during antipsychotic treatment and studied the ...
https://doi.org/10.1176/ajp.156.4.634Publication date: 01 April 1999
Pages637–639OBJECTIVE: Primary, enduring negative symptoms have been distinguished from negative symptoms more generally and are used to define the deficit syndrome of schizophrenia. Although the validity of the deficit syndrome has been demonstrated by using brain ...
https://doi.org/10.1176/ajp.156.4.637Publication date: 01 April 1999
Pages640–642OBJECTIVE: Diabetes mellitus has been implicated as a risk factor for tardive dyskinesia. The authors examined the association between abnormal movements and impaired glucose metabolism, which often precedes the development of overt diabetes, in patients ...
https://doi.org/10.1176/ajp.156.4.640Publication date: 01 April 1999
Pages643–645OBJECTIVE: The authors’ goal was to determine whether improved outcomes from enhanced acute-phase (3-month) treatment for depression in primary care persisted. METHOD: They conducted a 19-month follow-up assessment of 156 patients with major depression in ...
https://doi.org/10.1176/ajp.156.4.643Publication date: 01 April 1999
Pages646–649OBJECTIVE: This study was designed to assess possible antidepressant effects of dehydroepiandrosterone (DHEA), an abundant adrenocortical hormone in humans. METHOD: Twenty-two patients with major depression, either medication-free or on stabilized ...
https://doi.org/10.1176/ajp.156.4.646Publication date: 01 April 1999
Pages650–652OBJECTIVE: The authors’ goal was to determine whether early termination of breast-feeding contributes to later alcohol dependence, as proposed more than 200 years ago by the British physician Thomas Trotter. METHOD: In 1959–1961, a multiple-specialty ...
https://doi.org/10.1176/ajp.156.4.650