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American Journal of Psychiatry

  • Volume 158
  • Number 12
  • December 2001

Editorial

Reviews and Overviews

Publication date: 01 December 2001

Pages1956–1963

OBJECTIVE: The authors suggest that pharmacotherapy and psychotherapy, the major treatment modalities in psychiatry, have become fragmented from one another, creating an artificial separation of the psychosocial and biological domains in psychiatry. ...

https://doi.org/10.1176/appi.ajp.158.12.1956

Introspections

Clinical Case Conference

Images in Psychiatry

Article

Publication date: 01 December 2001

Pages1974–1981

OBJECTIVE: The study examined the efficacy of sertraline, compared with placebo, in sustaining improvement and preventing relapse over 28 weeks in patients with posttraumatic stress disorder (PTSD) who had completed a 12-week double-blind, placebo-...

https://doi.org/10.1176/appi.ajp.158.12.1974

Publication date: 01 December 2001

Pages1982–1988

OBJECTIVE: This study evaluated the efficacy and safety of paroxetine for the treatment of patients with chronic posttraumatic stress disorder (PTSD). METHOD: Outpatients with chronic PTSD according to DSM-IV criteria and a score of 50 or more on the ...

https://doi.org/10.1176/appi.ajp.158.12.1982

Publication date: 01 December 2001

Pages1989–1992

OBJECTIVE: Serotonin selective reuptake inhibitors (SSRIs) are now considered the first-line pharmacotherapy for panic disorder. The preferential use and the presumption of greater tolerability of SSRIs relative to older agents, such as tricyclic ...

https://doi.org/10.1176/appi.ajp.158.12.1989

Publication date: 01 December 2001

Pages1993–1998

OBJECTIVE: Recent studies have suggested that most patients treated for panic disorder receive forms of psychotherapy other than cognitive behavior therapy, even though there is little information about the efficacy of such treatments or how they compare ...

https://doi.org/10.1176/appi.ajp.158.12.1993

Publication date: 01 December 2001

Pages1999–2007

OBJECTIVE: The authors determined the costs associated with generalized social anxiety disorder in a managed care setting. METHOD: A three-phase mail and telephone survey was conducted from July to October 1998 in two outpatient clinics of a large health ...

https://doi.org/10.1176/appi.ajp.158.12.1999

Publication date: 01 December 2001

Pages2008–2014

OBJECTIVE: The study compared the safety and efficacy of sertraline, a selective serotonin reuptake inhibitor, and placebo in the treatment of generalized anxiety disorder in children and adolescents. METHOD: The study subjects were 22 children and ...

https://doi.org/10.1176/appi.ajp.158.12.2008

Publication date: 01 December 2001

Pages2022–2026

OBJECTIVE: The authors sought to clinically describe the relationship of disruptive behavior disorders with both alcohol dependence and the use of a variety of substances. METHOD: The Child Semi-Structured Assessment for the Genetics of Alcoholism was ...

https://doi.org/10.1176/appi.ajp.158.12.2022

Publication date: 01 December 2001

Pages2027–2032

OBJECTIVE: Recent policy has focused on documenting and reducing ethnic disparities in availability and quality of health care. The authors examined differences by ethnic status in unmet need for alcoholism, drug abuse, and mental health treatment. METHOD:...

https://doi.org/10.1176/appi.ajp.158.12.2027

Publication date: 01 December 2001

Pages2033–2037

OBJECTIVE: This study sought to estimate the degree to which cannabis abuse is a  risk factor for depressive symptoms rather than an effort to self-medicate depression. METHOD: Participants (N=1,920) in the 1980 Baltimore Epidemiologic Catchment Area (ECA)...

https://doi.org/10.1176/appi.ajp.158.12.2033

Publication date: 01 December 2001

Pages2038–2042

OBJECTIVE: This study evaluated the long-term outcome of cognitive behavior therapy versus relaxation therapy for patients with chronic fatigue syndrome. METHOD: Sixty patients who participated in a randomized controlled trial of cognitive behavior ...

https://doi.org/10.1176/appi.ajp.158.12.2038

Publication date: 01 December 2001

Pages2043–2047

OBJECTIVE: Insomnia and nightmares are perceived as secondary phenomena in posttraumatic stress disorder (PTSD). Scant treatment research has targeted these two sleep disturbances. This study reports on an open-label trial of cognitive behavior therapy ...

https://doi.org/10.1176/appi.ajp.158.12.2043

Publication date: 01 December 2001

Pages2048–2055

OBJECTIVE: Studies of depressed adults have shown abnormalities in cerebral energy metabolism, as noted by low brain levels of nucleoside triphosphate (NTP), which primarily represents adenosine triphosphate (ATP). This study was undertaken to determine ...

https://doi.org/10.1176/appi.ajp.158.12.2048

Publication date: 01 December 2001

Pages2056–2060

OBJECTIVE: The authors examined whether female stalkers differ from their male counterparts in psychopathology, motivation, behavior, and propensity for violence. METHOD: Female (N=40) and male (N=150) stalkers referred to a forensic mental health clinic ...

https://doi.org/10.1176/appi.ajp.158.12.2056

Publication date: 01 December 2001

Pages2061–2063

OBJECTIVE: In a large population-based study, the authors examined the prevalence and correlates of body dysmorphic disorder, a debilitating and chronic condition characterized by an imagined defect in appearance. METHOD: Rates and diagnostic correlates ...

https://doi.org/10.1176/appi.ajp.158.12.2061

Brief Report

Publication date: 01 December 2001

Pages2064–2066

OBJECTIVE: The relationship between subjective experience and behavior abnormalities in schizophrenia was investigated. METHOD: Eighteen patients with schizophrenia and 18 normal comparison subjects completed a general knowledge task with two incentive ...

https://doi.org/10.1176/appi.ajp.158.12.2064

Publication date: 01 December 2001

Pages2066–2068

OBJECTIVE: Two distinct measures have been used to assess inhibitory gating deficits in schizophrenia patients: P50 suppression and prepulse inhibition of the startle response. It remains unclear whether both measures can be assessed in a single testing ...

https://doi.org/10.1176/appi.ajp.158.12.2066

Publication date: 01 December 2001

Pages2069–2071

OBJECTIVE: Speaking is hypothesized to generate a corollary discharge of motor speech commands transmitted to the auditory cortex, dampening its response to self-generated speech sounds. Event-related potentials were used to test whether failures of ...

https://doi.org/10.1176/appi.ajp.158.12.2069

Publication date: 01 December 2001

Pages2071–2074

OBJECTIVE: This study determined if augmentation of neuroleptics with 3 g/day of ethyl eicosapentaenoic acid (EPA) improves symptoms and cognition in patients with schizophrenia or schizoaffective disorder. METHOD: Eighty-seven patients meeting criteria ...

https://doi.org/10.1176/appi.ajp.158.12.2071

Publication date: 01 December 2001

Pages2074–2076

OBJECTIVE: Depression has been associated with increased platelet activation. Variations in the serotonin-transporter-linked promoter region (5-HTTLPR) polymorphism may influence the degree of activation. The authors examined the association among ...

https://doi.org/10.1176/appi.ajp.158.12.2074

Publication date: 01 December 2001

Pages2077–2079

OBJECTIVE: Antidepressant use has increased in the last decade, but whether depression continues to be undertreated is unknown. The authors investigated the prevalence of antidepressant treatment and its predictors in a recent general population sample of ...

https://doi.org/10.1176/appi.ajp.158.12.2077

Publication date: 01 December 2001

Pages2080–2082

OBJECTIVE: Positron emission tomography (PET) was used to examine whether the dose of pindolol used to augment antidepressant medication achieves a significant occupancy of the serotonin type 1A (5-HT1A) autoreceptor in depressed patients receiving ...

https://doi.org/10.1176/appi.ajp.158.12.2080

Publication date: 01 December 2001

Pages2083–2085

OBJECTIVE: The authors tested the hypothesis that patients with major depression have a defect in the mechanism by which cortisol exerts negative feedback on the hypothalamic-pituitary-adrenal (HPA) axis during the HPA axis quiescent period. METHOD: ...

https://doi.org/10.1176/appi.ajp.158.12.2083

Letter to the Editor

Book Forum: Fiction

Book Forum: Photography

Book Forum: History

Book Forum: Autobiography and Biography

Book Forum: Understanding the Human Brain

Correction

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