American Journal of Psychiatry
- Volume 158
- Number 12
- December 2001
Editorial
Reviews and Overviews
Publication date: 01 December 2001
Pages1956–1963OBJECTIVE: The authors suggest that pharmacotherapy and psychotherapy, the major treatment modalities in psychiatry, have become fragmented from one another, creating an artificial separation of the psychosocial and biological domains in psychiatry. ...
https://doi.org/10.1176/appi.ajp.158.12.1956Introspections
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 December 2001
Pages1974–1981OBJECTIVE: The study examined the efficacy of sertraline, compared with placebo, in sustaining improvement and preventing relapse over 28 weeks in patients with posttraumatic stress disorder (PTSD) who had completed a 12-week double-blind, placebo-...
https://doi.org/10.1176/appi.ajp.158.12.1974Efficacy and Safety of Paroxetine Treatment for Chronic PTSD: A Fixed-Dose, Placebo-Controlled Study
Publication date: 01 December 2001
Pages1982–1988OBJECTIVE: This study evaluated the efficacy and safety of paroxetine for the treatment of patients with chronic posttraumatic stress disorder (PTSD). METHOD: Outpatients with chronic PTSD according to DSM-IV criteria and a score of 50 or more on the ...
https://doi.org/10.1176/appi.ajp.158.12.1982Publication date: 01 December 2001
Pages1989–1992OBJECTIVE: Serotonin selective reuptake inhibitors (SSRIs) are now considered the first-line pharmacotherapy for panic disorder. The preferential use and the presumption of greater tolerability of SSRIs relative to older agents, such as tricyclic ...
https://doi.org/10.1176/appi.ajp.158.12.1989Publication date: 01 December 2001
Pages1993–1998OBJECTIVE: Recent studies have suggested that most patients treated for panic disorder receive forms of psychotherapy other than cognitive behavior therapy, even though there is little information about the efficacy of such treatments or how they compare ...
https://doi.org/10.1176/appi.ajp.158.12.1993Publication date: 01 December 2001
Pages1999–2007OBJECTIVE: The authors determined the costs associated with generalized social anxiety disorder in a managed care setting. METHOD: A three-phase mail and telephone survey was conducted from July to October 1998 in two outpatient clinics of a large health ...
https://doi.org/10.1176/appi.ajp.158.12.1999Publication date: 01 December 2001
Pages2008–2014OBJECTIVE: The study compared the safety and efficacy of sertraline, a selective serotonin reuptake inhibitor, and placebo in the treatment of generalized anxiety disorder in children and adolescents. METHOD: The study subjects were 22 children and ...
https://doi.org/10.1176/appi.ajp.158.12.2008Publication date: 01 December 2001
Pages2015–2021OBJECTIVE: The role of dopamine in the addictive process (loss of control and compulsive drug intake) is poorly understood. A consistent finding in drug-addicted subjects is a lower level of dopamine D2 receptors. In cocaine abusers, low levels of D2 ...
https://doi.org/10.1176/appi.ajp.158.12.2015Publication date: 01 December 2001
Pages2022–2026OBJECTIVE: The authors sought to clinically describe the relationship of disruptive behavior disorders with both alcohol dependence and the use of a variety of substances. METHOD: The Child Semi-Structured Assessment for the Genetics of Alcoholism was ...
https://doi.org/10.1176/appi.ajp.158.12.2022Publication date: 01 December 2001
Pages2027–2032OBJECTIVE: Recent policy has focused on documenting and reducing ethnic disparities in availability and quality of health care. The authors examined differences by ethnic status in unmet need for alcoholism, drug abuse, and mental health treatment. METHOD:...
https://doi.org/10.1176/appi.ajp.158.12.2027Publication date: 01 December 2001
Pages2033–2037OBJECTIVE: This study sought to estimate the degree to which cannabis abuse is a risk factor for depressive symptoms rather than an effort to self-medicate depression. METHOD: Participants (N=1,920) in the 1980 Baltimore Epidemiologic Catchment Area (ECA)...
https://doi.org/10.1176/appi.ajp.158.12.2033Publication date: 01 December 2001
Pages2038–2042OBJECTIVE: This study evaluated the long-term outcome of cognitive behavior therapy versus relaxation therapy for patients with chronic fatigue syndrome. METHOD: Sixty patients who participated in a randomized controlled trial of cognitive behavior ...
https://doi.org/10.1176/appi.ajp.158.12.2038Publication date: 01 December 2001
Pages2043–2047OBJECTIVE: Insomnia and nightmares are perceived as secondary phenomena in posttraumatic stress disorder (PTSD). Scant treatment research has targeted these two sleep disturbances. This study reports on an open-label trial of cognitive behavior therapy ...
https://doi.org/10.1176/appi.ajp.158.12.2043Publication date: 01 December 2001
Pages2048–2055OBJECTIVE: Studies of depressed adults have shown abnormalities in cerebral energy metabolism, as noted by low brain levels of nucleoside triphosphate (NTP), which primarily represents adenosine triphosphate (ATP). This study was undertaken to determine ...
https://doi.org/10.1176/appi.ajp.158.12.2048Publication date: 01 December 2001
Pages2056–2060OBJECTIVE: The authors examined whether female stalkers differ from their male counterparts in psychopathology, motivation, behavior, and propensity for violence. METHOD: Female (N=40) and male (N=150) stalkers referred to a forensic mental health clinic ...
https://doi.org/10.1176/appi.ajp.158.12.2056Publication date: 01 December 2001
Pages2061–2063OBJECTIVE: In a large population-based study, the authors examined the prevalence and correlates of body dysmorphic disorder, a debilitating and chronic condition characterized by an imagined defect in appearance. METHOD: Rates and diagnostic correlates ...
https://doi.org/10.1176/appi.ajp.158.12.2061Brief Report
Publication date: 01 December 2001
Pages2064–2066OBJECTIVE: The relationship between subjective experience and behavior abnormalities in schizophrenia was investigated. METHOD: Eighteen patients with schizophrenia and 18 normal comparison subjects completed a general knowledge task with two incentive ...
https://doi.org/10.1176/appi.ajp.158.12.2064Publication date: 01 December 2001
Pages2066–2068OBJECTIVE: Two distinct measures have been used to assess inhibitory gating deficits in schizophrenia patients: P50 suppression and prepulse inhibition of the startle response. It remains unclear whether both measures can be assessed in a single testing ...
https://doi.org/10.1176/appi.ajp.158.12.2066Publication date: 01 December 2001
Pages2069–2071OBJECTIVE: Speaking is hypothesized to generate a corollary discharge of motor speech commands transmitted to the auditory cortex, dampening its response to self-generated speech sounds. Event-related potentials were used to test whether failures of ...
https://doi.org/10.1176/appi.ajp.158.12.2069Publication date: 01 December 2001
Pages2071–2074OBJECTIVE: This study determined if augmentation of neuroleptics with 3 g/day of ethyl eicosapentaenoic acid (EPA) improves symptoms and cognition in patients with schizophrenia or schizoaffective disorder. METHOD: Eighty-seven patients meeting criteria ...
https://doi.org/10.1176/appi.ajp.158.12.2071Publication date: 01 December 2001
Pages2074–2076OBJECTIVE: Depression has been associated with increased platelet activation. Variations in the serotonin-transporter-linked promoter region (5-HTTLPR) polymorphism may influence the degree of activation. The authors examined the association among ...
https://doi.org/10.1176/appi.ajp.158.12.2074Publication date: 01 December 2001
Pages2077–2079OBJECTIVE: Antidepressant use has increased in the last decade, but whether depression continues to be undertreated is unknown. The authors investigated the prevalence of antidepressant treatment and its predictors in a recent general population sample of ...
https://doi.org/10.1176/appi.ajp.158.12.2077Publication date: 01 December 2001
Pages2080–2082OBJECTIVE: Positron emission tomography (PET) was used to examine whether the dose of pindolol used to augment antidepressant medication achieves a significant occupancy of the serotonin type 1A (5-HT1A) autoreceptor in depressed patients receiving ...
https://doi.org/10.1176/appi.ajp.158.12.2080Publication date: 01 December 2001
Pages2083–2085OBJECTIVE: The authors tested the hypothesis that patients with major depression have a defect in the mechanism by which cortisol exerts negative feedback on the hypothalamic-pituitary-adrenal (HPA) axis during the HPA axis quiescent period. METHOD: ...
https://doi.org/10.1176/appi.ajp.158.12.2083Letter to the Editor
Book Forum: Fiction
Book Forum: Photography
Book Forum: History
Book Forum: Autobiography and Biography
Book Forum: Understanding the Human Brain
Correction
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