American Journal of Psychiatry
- Volume 158
- Number 11
- November 2001
Editorial
Reviews and Overviews
Publication date: 01 November 2001
Pages1774–1782OBJECTIVE: The authors review the mechanisms and establish the risk of torsade de pointes and sudden death with antipsychotic drugs. METHOD: They present a review of original concepts, the distinction between familial and drug-induced cases of torsade de ...
https://doi.org/10.1176/appi.ajp.158.11.1774Publication date: 01 November 2001
Pages1783–1793OBJECTIVE: The authors discuss the relationship of impulsivity to psychiatric disorders and present selected hypotheses regarding the reasons for these relationships. METHOD: Previous research has shown significantly higher levels of impulsivity among ...
https://doi.org/10.1176/appi.ajp.158.11.1783Introspections
Images in Psychiatry
Article
Publication date: 01 November 2001
Pages1797–1808OBJECTIVE: Using functional brain imaging, the authors sought to replicate their earlier finding of low metabolism in the middle frontal and inferior parietal cortices of schizophrenic patients with primary negative symptoms. METHOD: According to the ...
https://doi.org/10.1176/appi.ajp.158.11.1797Publication date: 01 November 2001
Pages1809–1817OBJECTIVE: Disturbed neuronal interactions may be involved in schizophrenia because it is without clear regional pathology. Aberrant connectivity is further suggested by theoretical formulations and neurochemical and neuroanatomical data. The authors ...
https://doi.org/10.1176/appi.ajp.158.11.1809Publication date: 01 November 2001
Pages1818–1826OBJECTIVE: Individuals are able to recognize common objects even when portions of them are obscured from view, reflecting the operation of neural perceptual closure processes. This study evaluates the integrity of object recognition and perceptual closure ...
https://doi.org/10.1176/appi.ajp.158.11.1818Publication date: 01 November 2001
Pages1827–1834OBJECTIVE: First-degree relatives of patients with schizophrenia appear to have subtle neurological signs, suggesting that these measures could serve as intermediate phenotypes in genetic studies of schizophrenia. The strength of a possible genetic ...
https://doi.org/10.1176/appi.ajp.158.11.1827Publication date: 01 November 2001
Pages1835–1842OBJECTIVE: The goal of this report was to examine the clinical course following neuroleptic discontinuation of patients with recent-onset schizophrenia who had been receiving maintenance antipsychotic treatment for at least 1 year. METHOD: Fifty-three ...
https://doi.org/10.1176/appi.ajp.158.11.1835Publication date: 01 November 2001
Pages1843–1849OBJECTIVE: Selective serotonin reuptake inhibitors are commonly used to treat major depression; however, the percentage of serotonin (5-HT) transporter (5-HTT) sites occupied during clinical dosing is unknown. This study measured the proportion of 5-HTT ...
https://doi.org/10.1176/appi.ajp.158.11.1843Publication date: 01 November 2001
Pages1850–1855OBJECTIVE: This study tested whether social support protects against functional decline, either generally or selectively, in the most severely depressed elderly patients undergoing treatment for major depressive disorder. METHOD: In a prospective cohort ...
https://doi.org/10.1176/appi.ajp.158.11.1850Publication date: 01 November 2001
Pages1856–1863OBJECTIVE: Postpartum depressive disorders lead to maternal disability and disturbed mother-infant relationships, but information regarding the rates of major depressive disorder in minority women is noticeably lacking. The goal of this study was to ...
https://doi.org/10.1176/appi.ajp.158.11.1856Publication date: 01 November 2001
Pages1864–1870OBJECTIVE: This study sought to identify predictors of course and outcome in dysthymic disorder. METHOD: Eighty-six outpatients with early-onset dysthymic disorder (before age 21) participated in a prospective 5-year follow-up study. Family history of ...
https://doi.org/10.1176/appi.ajp.158.11.1864Publication date: 01 November 2001
Pages1871–1877OBJECTIVE: This study investigated whether a higher frequency of reported childhood trauma would be found in depressed adults with higher levels of trait impulsivity, aggression, and suicidal behavior. METHOD: In 136 depressed adult inpatients, the ...
https://doi.org/10.1176/appi.ajp.158.11.1871Publication date: 01 November 2001
Pages1878–1883OBJECTIVE: The authors assessed lifetime psychopathology in a general population sample and compared the rates of five psychiatric disorder categories between those who reported a childhood history of either physical or sexual abuse and those who did not. ...
https://doi.org/10.1176/appi.ajp.158.11.1878Publication date: 01 November 2001
Pages1884–1890OBJECTIVE: The authors investigated whether deficient inhibitory control, as measured by the stop-signal paradigm, delineates a familial subgroup of attention deficit hyperactivity disorder (ADHD). METHOD: Subjects were 54 ADHD children defined as having ...
https://doi.org/10.1176/appi.ajp.158.11.1884Publication date: 01 November 2001
Pages1891–1898OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a highly heritable but clinically heterogeneous syndrome. The study examined the familiality and heritability of ADHD subtypes as defined by DSM-IV and by latent-class analysis in a population ...
https://doi.org/10.1176/appi.ajp.158.11.1891Publication date: 01 November 2001
Pages1899–1903OBJECTIVE: Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder with a bimodal age at onset and range of treatment outcomes. This study attempted to ascertain the importance of the age at OCD symptom onset for a better phenotypic ...
https://doi.org/10.1176/appi.ajp.158.11.1899Publication date: 01 November 2001
Pages1904–1910OBJECTIVE: Little is known about the prevalence of obsessive-compulsive disorder (OCD) as recognized in clinical settings. The authors report data on the prevalence of clinically recognized OCD in a large, integrated, group practice health maintenance ...
https://doi.org/10.1176/appi.ajp.158.11.1904Brief Report
Publication date: 01 November 2001
Pages1911–1913OBJECTIVE: The ability of individuals with schizophrenia to provide informed consent for research has become the focus of public debate. The authors examined whether a novel consent procedure improved the comprehension of consent for older patients with ...
https://doi.org/10.1176/appi.ajp.158.11.1911Publication date: 01 November 2001
Pages1914–1916OBJECTIVE: The study assessed the effects of inner speech on auditory cortical responsiveness in schizophrenia. METHOD: Comparison subjects (N=15) and patients with schizophrenia (N=15) were presented with acoustic and visual stimuli during three ...
https://doi.org/10.1176/appi.ajp.158.11.1914Publication date: 01 November 2001
Pages1917–1919OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment. METHOD: Two study ...
https://doi.org/10.1176/appi.ajp.158.11.1917Publication date: 01 November 2001
Pages1920–1922OBJECTIVE: The neuronal circuitry underlying posttraumatic stress disorder (PTSD) was studied in traumatized subjects with and without PTSD. METHOD: Traumatized subjects with (N=9) and without (N=9) PTSD were studied by using the script-driven symptom ...
https://doi.org/10.1176/appi.ajp.158.11.1920Publication date: 01 November 2001
Pages1923–1925OBJECTIVE: This report examined gender differences in the clinical manifestations of current posttraumatic stress disorder (PTSD) in treatment-seeking patients. METHOD: Outpatients with PTSD (N=138) were interviewed with the Structured Clinical Interview ...
https://doi.org/10.1176/appi.ajp.158.11.1923Publication date: 01 November 2001
Pages1926–1928OBJECTIVE: This study was an evaluation of whether sildenafil citrate is effective for the treatment of erectile dysfunction in men taking concomitant serotonin-reuptake-inhibiting antidepressants. METHOD: A retrospective subanalysis of combined data from ...
https://doi.org/10.1176/appi.ajp.158.11.1926