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American Journal of Psychiatry

  • Volume 158
  • Number 11
  • November 2001

Editorial

Reviews and Overviews

Publication date: 01 November 2001

Pages1774–1782

OBJECTIVE: The authors review the mechanisms and establish the risk of torsade de pointes and sudden death with antipsychotic drugs. METHOD: They present a review of original concepts, the distinction between familial and drug-induced cases of torsade de ...

https://doi.org/10.1176/appi.ajp.158.11.1774

Publication date: 01 November 2001

Pages1783–1793

OBJECTIVE: The authors discuss the relationship of impulsivity to psychiatric disorders and present selected hypotheses regarding the reasons for these relationships. METHOD: Previous research has shown significantly higher levels of impulsivity among ...

https://doi.org/10.1176/appi.ajp.158.11.1783

Introspections

Images in Psychiatry

Article

Publication date: 01 November 2001

Pages1797–1808

OBJECTIVE: Using functional brain imaging, the authors sought to replicate their earlier finding of low metabolism in the middle frontal and inferior parietal cortices of schizophrenic patients with primary negative symptoms. METHOD: According to the ...

https://doi.org/10.1176/appi.ajp.158.11.1797

Publication date: 01 November 2001

Pages1809–1817

OBJECTIVE: Disturbed neuronal interactions may be involved in schizophrenia because it is without clear regional pathology. Aberrant connectivity is further suggested by theoretical formulations and neurochemical and neuroanatomical data. The authors ...

https://doi.org/10.1176/appi.ajp.158.11.1809

Publication date: 01 November 2001

Pages1818–1826

OBJECTIVE: Individuals are able to recognize common objects even when portions of them are obscured from view, reflecting the operation of neural perceptual closure processes. This study evaluates the integrity of object recognition and perceptual closure ...

https://doi.org/10.1176/appi.ajp.158.11.1818

Publication date: 01 November 2001

Pages1827–1834

OBJECTIVE: First-degree relatives of patients with schizophrenia appear to have subtle neurological signs, suggesting that these measures could serve as intermediate phenotypes in genetic studies of schizophrenia. The strength of a possible genetic ...

https://doi.org/10.1176/appi.ajp.158.11.1827

Publication date: 01 November 2001

Pages1835–1842

OBJECTIVE: The goal of this report was to examine the clinical course following neuroleptic discontinuation of patients with recent-onset schizophrenia who had been receiving maintenance antipsychotic treatment for at least 1 year. METHOD: Fifty-three ...

https://doi.org/10.1176/appi.ajp.158.11.1835

Publication date: 01 November 2001

Pages1843–1849

OBJECTIVE: Selective serotonin reuptake inhibitors are commonly used to treat major depression; however, the percentage of serotonin (5-HT) transporter (5-HTT) sites occupied during clinical dosing is unknown. This study measured the proportion of 5-HTT ...

https://doi.org/10.1176/appi.ajp.158.11.1843

Publication date: 01 November 2001

Pages1850–1855

OBJECTIVE: This study tested whether social support protects against functional decline, either generally or selectively, in the most severely depressed elderly patients undergoing treatment for major depressive disorder. METHOD: In a prospective cohort ...

https://doi.org/10.1176/appi.ajp.158.11.1850

Publication date: 01 November 2001

Pages1856–1863

OBJECTIVE: Postpartum depressive disorders lead to maternal disability and disturbed mother-infant relationships, but information regarding the rates of major depressive disorder in minority women is noticeably lacking. The goal of this study was to ...

https://doi.org/10.1176/appi.ajp.158.11.1856

Publication date: 01 November 2001

Pages1864–1870

OBJECTIVE: This study sought to identify predictors of course and outcome in dysthymic disorder. METHOD: Eighty-six outpatients with early-onset dysthymic disorder (before age 21) participated in a prospective 5-year follow-up study. Family history of ...

https://doi.org/10.1176/appi.ajp.158.11.1864

Publication date: 01 November 2001

Pages1871–1877

OBJECTIVE: This study investigated whether a higher frequency of reported childhood trauma would be found in depressed adults with higher levels of trait impulsivity, aggression, and suicidal behavior. METHOD: In 136 depressed adult inpatients, the ...

https://doi.org/10.1176/appi.ajp.158.11.1871

Publication date: 01 November 2001

Pages1878–1883

OBJECTIVE: The authors assessed lifetime psychopathology in a general population sample and compared the rates of five psychiatric disorder categories between those who reported a childhood history of either physical or sexual abuse and those who did not. ...

https://doi.org/10.1176/appi.ajp.158.11.1878

Publication date: 01 November 2001

Pages1884–1890

OBJECTIVE: The authors investigated whether deficient inhibitory control, as measured by the stop-signal paradigm, delineates a familial subgroup of attention deficit hyperactivity disorder (ADHD). METHOD: Subjects were 54 ADHD children defined as having ...

https://doi.org/10.1176/appi.ajp.158.11.1884

Publication date: 01 November 2001

Pages1891–1898

OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a highly heritable but clinically heterogeneous syndrome. The study examined the familiality and heritability of ADHD subtypes as defined by DSM-IV and by latent-class analysis in a population ...

https://doi.org/10.1176/appi.ajp.158.11.1891

Publication date: 01 November 2001

Pages1899–1903

OBJECTIVE: Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder with a bimodal age at onset and range of treatment outcomes. This study attempted to ascertain the importance of the age at OCD symptom onset for a better phenotypic ...

https://doi.org/10.1176/appi.ajp.158.11.1899

Publication date: 01 November 2001

Pages1904–1910

OBJECTIVE: Little is known about the prevalence of obsessive-compulsive disorder (OCD) as recognized in clinical settings. The authors report data on the prevalence of clinically recognized OCD in a large, integrated, group practice health maintenance ...

https://doi.org/10.1176/appi.ajp.158.11.1904

Brief Report

Publication date: 01 November 2001

Pages1911–1913

OBJECTIVE: The ability of individuals with schizophrenia to provide informed consent for research has become the focus of public debate. The authors examined whether a novel consent procedure improved the comprehension of consent for older patients with ...

https://doi.org/10.1176/appi.ajp.158.11.1911

Publication date: 01 November 2001

Pages1914–1916

OBJECTIVE: The study assessed the effects of inner speech on auditory cortical responsiveness in schizophrenia. METHOD: Comparison subjects (N=15) and patients with schizophrenia (N=15) were presented with acoustic and visual stimuli during three ...

https://doi.org/10.1176/appi.ajp.158.11.1914

Publication date: 01 November 2001

Pages1917–1919

OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment. METHOD: Two study ...

https://doi.org/10.1176/appi.ajp.158.11.1917

Publication date: 01 November 2001

Pages1920–1922

OBJECTIVE: The neuronal circuitry underlying posttraumatic stress disorder (PTSD) was studied in traumatized subjects with and without PTSD. METHOD: Traumatized subjects with (N=9) and without (N=9) PTSD were studied by using the script-driven symptom ...

https://doi.org/10.1176/appi.ajp.158.11.1920

Publication date: 01 November 2001

Pages1923–1925

OBJECTIVE: This report examined gender differences in the clinical manifestations of current posttraumatic stress disorder (PTSD) in treatment-seeking patients. METHOD: Outpatients with PTSD (N=138) were interviewed with the Structured Clinical Interview ...

https://doi.org/10.1176/appi.ajp.158.11.1923

Publication date: 01 November 2001

Pages1926–1928

OBJECTIVE: This study was an evaluation of whether sildenafil citrate is effective for the treatment of erectile dysfunction in men taking concomitant serotonin-reuptake-inhibiting antidepressants. METHOD: A retrospective subanalysis of combined data from ...

https://doi.org/10.1176/appi.ajp.158.11.1926

Letter to the Editor

Book Forum: Life Stories

Book Forum: Women and Men: Gender Issues

Book Forum: Dementias

Book Forum: Forensic Topics

Correction

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