American Journal of Psychiatry
- Volume 159
- Number 5
- May 2002
Editorial
Reviews and Overviews
Publication date: 01 May 2002
Pages695–704OBJECTIVE: This article examines the historical basis for the divergence of neurology and psychiatry over the past century and discusses prospects for a rapprochement and potential convergence of the two specialties in the next century. METHOD: The author ...
https://doi.org/10.1176/appi.ajp.159.5.695Publication date: 01 May 2002
Pages705–712OBJECTIVE: Informed consent is built upon the elements of information, decisional capacity, and voluntarism. Of these elements, voluntarism in clinical and research consent is the least well understood. This has interfered with the ability to resolve key ...
https://doi.org/10.1176/appi.ajp.159.5.705Publication date: 01 May 2002
Pages713–719OBJECTIVE: Onset of schizophrenia occurs during the reproductive period in more than 80% of those affected. The author reviews neuroendocrine and physiologic events that occur in the basal forebrain at the initiation of and throughout the reproductive ...
https://doi.org/10.1176/appi.ajp.159.5.713Images in Neuroscience
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 May 2002
Pages728–737OBJECTIVE: Administration of placebo can result in a clinical response indistinguishable from that seen with active antidepressant treatment. Functional brain correlates of this phenomenon have not been fully characterized. METHOD: Changes in brain ...
https://doi.org/10.1176/appi.ajp.159.5.728Publication date: 01 May 2002
Pages738–745OBJECTIVE: It is well established that regional cerebral metabolic rates for glucose assessed by [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) in patients with Alzheimer’s disease in the mental resting state (eyes and ears covered) ...
https://doi.org/10.1176/appi.ajp.159.5.738Publication date: 01 May 2002
Pages746–754OBJECTIVE: A multivariate analysis of baseline brain metabolism was used to investigate the relationships among pathophysiological mechanisms responsible for cognitive dysfunction and dysphoria in nondemented patients with Parkinson’s disease. METHOD: ...
https://doi.org/10.1176/appi.ajp.159.5.746Publication date: 01 May 2002
Pages755–760OBJECTIVE: Pediatric populations, including those with autistic disorder or other pervasive developmental disorders, increasingly are being prescribed selective serotonin reuptake inhibitors (SSRIs). Little is known about the age-related brain ...
https://doi.org/10.1176/appi.ajp.159.5.755Publication date: 01 May 2002
Pages761–767OBJECTIVE: Postmortem studies and a positron emission tomography (PET) study have suggested that there is a disturbance of central D1 dopamine receptor function in schizophrenia. The objective of the present PET study was to compare D1 receptor binding in ...
https://doi.org/10.1176/appi.ajp.159.5.761Publication date: 01 May 2002
Pages768–774OBJECTIVE: Although dopaminergic hyperactivity has been implicated in mania, the precise location in the brain of the abnormality is unclear. This study assessed presynaptic dopamine function in neuroleptic- and mood-stabilizer-naive nonpsychotic first-...
https://doi.org/10.1176/appi.ajp.159.5.768Publication date: 01 May 2002
Pages775–783OBJECTIVE: This research extends a series of studies that have examined the process of psychotherapy. The authors hypothesized that manualized regimens of psychotherapy compared in a controlled clinical trial would overlap considerably in process and ...
https://doi.org/10.1176/appi.ajp.159.5.775Publication date: 01 May 2002
Pages784–788OBJECTIVE: This study sought to understand affective instability among patients with borderline personality disorder by examining the degree of instability in six affective domains. The authors also examined the subjective intensity with which moods are ...
https://doi.org/10.1176/appi.ajp.159.5.784Publication date: 01 May 2002
Pages789–796OBJECTIVE: This study examined whether there were differences in the rate of depressive and anxiety disorders between HIV-infected women (N=93) and a comparison group of uninfected women (N=62). Secondary objectives were to examine correlates of ...
https://doi.org/10.1176/appi.ajp.159.5.789Publication date: 01 May 2002
Pages797–802OBJECTIVE: Ethical concerns persist over research participation of decisionally impaired persons, such as those suffering from Alzheimer’s disease. Such persons may be poor judges of the burdens and risks of specific research protocols. Since even ...
https://doi.org/10.1176/appi.ajp.159.5.797Publication date: 01 May 2002
Pages803–812OBJECTIVE: Some genome-wide scans and association studies for schizophrenia susceptibility genes have yielded significant positive findings, but there is disagreement between studies on their locations, and no mutation has yet been found in any gene. ...
https://doi.org/10.1176/appi.ajp.159.5.803Publication date: 01 May 2002
Pages813–820OBJECTIVE: Disruptions in connectivity between the frontal and temporal lobes may explain some of the symptoms observed in schizophrenia. Conventional magnetic resonance imaging (MRI) studies, however, have not shown compelling evidence for white matter ...
https://doi.org/10.1176/appi.ajp.159.5.813Publication date: 01 May 2002
Pages821–828OBJECTIVE: It has been suggested that the primary focus of the pathological process in schizophrenia is on the limbic system, and there have been several postmortem reports of changes in the histological structure or volume of the hippocampus, as well as ...
https://doi.org/10.1176/appi.ajp.159.5.821Publication date: 01 May 2002
Pages829–837OBJECTIVE: Although skills training is a validated psychosocial treatment for schizophrenia, generalization of the skills to everyday life has not been optimal. This study evaluated a behaviorally oriented method of augmenting clinic-based skills training ...
https://doi.org/10.1176/appi.ajp.159.5.829Publication date: 01 May 2002
Pages838–844OBJECTIVE: The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) was designed as a cognitive screening test, providing both a total scale score and five specific cognitive ability index scores. This study examined the test-retest ...
https://doi.org/10.1176/appi.ajp.159.5.838Publication date: 01 May 2002
Pages845–851OBJECTIVE: The authors interviewed individuals treated for self-described mental health problems in the preceding year to examine patterns and predictors associated with dropping out of treatment. METHOD: Subjects were drawn from respondents to community ...
https://doi.org/10.1176/appi.ajp.159.5.845Brief Report
Publication date: 01 May 2002
Pages852–854OBJECTIVE: The study tested the effect of comorbid posttraumatic stress disorder (PTSD) on behavior therapy outcome for obsessive-compulsive disorder (OCD). METHOD: Subjects were 15 patients with treatment-refractory OCD who were admitted consecutively to ...
https://doi.org/10.1176/appi.ajp.159.5.852Publication date: 01 May 2002
Pages855–857OBJECTIVE: Disturbed sleep is a common complaint among patients with posttraumatic stress disorder (PTSD) that appears in the reexperiencing and hyperarousal symptom clusters in DSM-IV. The causal relationship between sleep complaints and PTSD is unclear. ...
https://doi.org/10.1176/appi.ajp.159.5.855Publication date: 01 May 2002
Pages857–859OBJECTIVE: Psychiatric disorders were studied in a volunteer group of 181 firefighters who served as rescue/recovery workers after the Oklahoma City bombing. METHOD: Approximately 34 months after the disaster, the authors retrospectively assessed ...
https://doi.org/10.1176/appi.ajp.159.5.857Publication date: 01 May 2002
Pages860–862OBJECTIVE: This study examined the rates and correlates of mental health care performance measures in the Health Employer Data and Information Set (HEDIS). METHOD: For all 384 health maintenance organizations (HMOs) participating in the HEDIS program of ...
https://doi.org/10.1176/appi.ajp.159.5.860Publication date: 01 May 2002
Pages863–865OBJECTIVE: This study was conducted to determine the interrater reliability and predictive validity of a set of diagnostic criteria for the prodrome of the first episode of schizophrenic psychosis when based on the Structured Interview for Prodromal ...
https://doi.org/10.1176/appi.ajp.159.5.863Publication date: 01 May 2002
Pages866–868OBJECTIVE: The corpus callosum, the largest white matter tract in the brain, is a midline structure associated with the formation of the hippocampus, septum pellucidum, and cingulate cortex, which have been implicated in the pathogenesis of schizophrenia. ...
https://doi.org/10.1176/appi.ajp.159.5.866Publication date: 01 May 2002
Pages869–871OBJECTIVE: Subjects with schizotypal personality disorder demonstrate deficits in inhibition when assessed on prepulse inhibition, P50 suppression, and antisaccade paradigms. This study determined if distinct subgroups of subjects with schizotypal ...
https://doi.org/10.1176/appi.ajp.159.5.869