The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 27
- Number 2
- April 2015
Windows to the Brain
Editorial
Features
Special Articles
Publication date: 09 March 2015
Pages81–92The majority of neuropsychiatric disorders show a strong degree of heritability, yet little is known about molecular factors involved in the pathophysiology of diseases like schizophrenia. After a brief historical introduction into the current ...
https://doi.org/10.1176/appi.neuropsych.13080185Publication date: 01 April 2015
Pages93–103The authors describe a spectrum disorder comprising a core anxiety (A) disorder and four domains: joint laxity (L), chronic pain syndromes (P), immune disorders (I), and mood disorders (M)—dubbed the ALPIM syndrome. This study examined 76 consecutive ...
https://doi.org/10.1176/appi.neuropsych.14060132Publication date: 01 April 2015
Pages104–111Major depressive disorder continues to challenge medical and psychological resources worldwide. A marked surge has occurred recently in China in neuroimaging studies of major depressive disorder. Those studies represent an emerging trend in ...
https://doi.org/10.1176/appi.neuropsych.13110343Features
Regular Articles
Publication date: 01 April 2015
Pages112–120This study aimed to better understand the occurrence of novel psychiatric disorders (NPDs) in children with mild traumatic brain injury (mTBI) in relation to preinjury variables, injury-related variables, and concurrent neurocognitive outcome. Eighty-...
https://doi.org/10.1176/appi.neuropsych.13080190Publication date: 01 April 2015
Pages121–126Recent studies suggest that depression and anxiety in patients with Parkinson’s disease may predispose them to freezing. Although festination is also frequent, the association with emotional disorders has not been examined. The aim of the authors was to ...
https://doi.org/10.1176/appi.neuropsych.13030053Publication date: 09 March 2015
Pages127–132Mental imagery impairment has been reported in schizophrenia. The present study aimed to investigate the neural evidence for mental imagery impairment in patients with schizophrenia. The study participants included 20 patients with chronic schizophrenia ...
https://doi.org/10.1176/appi.neuropsych.13120392Publication date: 01 April 2015
Pages133–138Autism spectrum disorders are difficult for older adolescents and young adults as impaired social communication affects the transition to adult life. d-Cycloserine, a partial glycine agonist at the N-methyl-d-aspartic acid receptor, was tested in a double-...
https://doi.org/10.1176/appi.neuropsych.13070155Publication date: 01 April 2015
Pages139–146A total of 203 consecutive patients were assessed on a delirium experience questionnaire 24 hours after recovery from delirium. One third (35%) of the patients could recollect their experiences during the delirium, and the majority (86%) of them were ...
https://doi.org/10.1176/appi.neuropsych.13110329Publication date: 01 April 2015
Pages147–152This study is an expanded version of an earlier study, which compared NeuroQuant measures of MRI brain volume with the radiologist’s traditional approach in outpatients with mild or moderate traumatic brain injury. NeuroQuant volumetric analyses were ...
https://doi.org/10.1176/appi.neuropsych.13040088Features
Clinical and Research Reports
Publication date: 01 April 2015
Pages153–156In recently depressed adolescents, attention and emotional reactivity improved significantly compared with baseline. Working memory did not improve. This supports the position that, in adolescent depression, attention is state dependent compared with ...
https://doi.org/10.1176/appi.neuropsych.13120372Publication date: 09 March 2015
Pages157–161Apolipoprotien E (ApoE) is involved in critical neural functions and is associated with various neuropsychiatric disorders. ApoE exists in three isoforms that differ in the number of cysteine residues per mole (CysR/mole). This study evaluated ...
https://doi.org/10.1176/appi.neuropsych.13090205Publication date: 01 April 2015
Pages162–164Association between gastric inhibitory polypeptide receptor polymorphism, rs10423928, and body mass index in olanzapine-treated schizophrenia was examined. Body mass index change for the A/T+A/A genotypes was significantly higher than that for the T/T ...
https://doi.org/10.1176/appi.neuropsych.13120389Online Exclusives
Publication date: 26 December 2014
Pagese92–e96Early cell death is a feature of neurodegenerative disorders. Telomere shortening is related to premature cellular senescence and could be a marker for cellular pathology in neurological diseases. Relative telomere length in dementia (N=70), Huntington’s ...
https://doi.org/10.1176/appi.neuropsych.13100240Publication date: 26 December 2014
Pagese97–e99Pituitary volume is considered to reflect hypothalamic-pituitary-adrenal axis dysregulation, and this has been studied in various psychiatric disorders. This study demonstrates that pituitary volume as assessed through the region of interest manual ...
https://doi.org/10.1176/appi.neuropsych.13080188Publication date: 01 April 2015
Pagese100–e106Temporal lobe epilepsy is considered to be the most frequent of all epileptic syndromes. Recently, several retrospective studies suggest that limbic encephalitis (LE) may be a cause for adult onset unexplained seizure disorders in patients. This report ...
https://doi.org/10.1176/appi.neuropsych.13070158Publication date: 12 December 2014
Pagese107–e111This study identified 37,810 patients with anxiety or sleep disorder (mean age=53.2 years, SD=16.0 years) who had zolpidem prescribed for at least 2 months from January 1, 2000 through December 31, 2009. Another non-zolpidem cohort was selected by 1:1 ...
https://doi.org/10.1176/appi.neuropsych.14010006Publication date: 26 December 2014
Pagese112–e116Sympathovagal balance, assessed with heart rate variability (HRV), may be altered in intensive care unit (ICU) delirium. HRV was measured in the frequency domain [low frequencies (LF)=0.04–0.15 Hz and high frequencies (HF)=0.15–0.40 Hz] with HF in ...
https://doi.org/10.1176/appi.neuropsych.13090213Publication date: 26 December 2014
Pagese117–e121In late life, neurological disturbances, depression, and anxiety frequently complicate the clinical presentation but are often undertreated. An administrative database of 3,034 male veterans, age 55 years and older, with a diagnosis of dementia, Parkinson’...
https://doi.org/10.1176/appi.neuropsych.13110333Publication date: 01 April 2015
Pagese122–e127Principal components analysis applied to the Delirium Rating Scale-Revised-98 contributes to understanding the delirium construct. Using a multisite pooled international delirium database, the authors applied confirmatory factor analysis to Delirium ...
https://doi.org/10.1176/appi.neuropsych.13110345Publication date: 01 April 2015
Pagese128–e133In this study, the authors report superior temporal gyrus (STG) and Heschl’s gyrus (HG) volume deficits in a large sample of medication-naïve patients with schizophrenia (N=55) in comparison with healthy control subjects (N=45) with structural MRI using ...
https://doi.org/10.1176/appi.neuropsych.14030049Publication date: 12 December 2014
Pagese134–e139Psychiatric manifestations of Parkinson’s disease (PD) are a cause of significant disability and the impact of dopaminergic medications is unclear. Using standardized rating scales, the authors tested the hypothesis that anxiety, depression, and apathy ...
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